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Query: PRKCQ

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRKCQ 0 0.911 0.410 0.020

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRKCQ Phosphorylation S685 0.911 _ALINS(ph)MDQNMFR_

Background Information for PRKCQ:


Pubmed-PRKCQ »
Uniprot-PRKCQ »
Biogrid-PRKCQ »
ProteomicsDB-PRKCQ »

Tumorportal-PRKCQ »
COSMIC-PRKCQ »
GenomeRNAi-PRKCQ »
Genecards-PRKCQ


Protein-protein Interactions for PRKCQ
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DEF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKCQ Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRKCQ
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PE/DAG-bd IPR002219 0.63
Category members DAG/PE-bd IPR020454 0.18
Category members Kinase-like_dom IPR011009 0.03
Category members C2_dom IPR000008 0
Category members Prot_kinase_dom IPR000719 0
Category members AGC-kinase_C IPR000961 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Prot_kin_PKC_delta IPR014376 0
Category members Pkinase_C IPR017892 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring PRKCQ
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRKCQ
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0006921 cellular component disassembly involved in execution phase of apoptosis Database 2.98
Category members Pathway Pathway_876 REACTOME_APOPTOTIC_EXECUTION_PHASE 0 2.5
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members Pathway Pathway_1023 PID_NFAT_3PATHWAY 0 1.46
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members Pathway Pathway_877 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0070233 negative regulation of T cell apoptotic process Database 0.47
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0038095 Fc-epsilon receptor signaling pathway Database 0.36
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0007603 phototransduction, visible light Database 0.25
Category members Pathway Pathway_587 KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.25
Category members Pathway Pathway_228 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS 0 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members Pathway Pathway_573 REACTOME_TCR_SIGNALING 0 0.2
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_485 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS 0 0.18
Category members Pathway Pathway_705 PID_CD8_TCR_PATHWAY 0 0.17
Category members GO Category GO:0006509 membrane protein ectodomain proteolysis Database 0.14
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0050870 positive regulation of T cell activation Database 0.13
Category members Pathway Pathway_56 REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 0 0.11
Category members GO Category GO:0004697 protein kinase C activity Database 0.09
Category members Pathway Pathway_687 PID_TCR_PATHWAY 0 0.08
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0050852 T cell receptor signaling pathway Database 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0042102 positive regulation of T cell proliferation Database 0.04
Category members Pathway Pathway_486 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 0 0.04
Category members GO Category GO:0016056 rhodopsin mediated signaling pathway Database 0.04
Category members Pathway Pathway_160 KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION 0 0.01
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0022400 regulation of rhodopsin mediated signaling pathway Database 0
Category members Pathway Pathway_1048 BIOCARTA_KERATINOCYTE_PATHWAY 0 0
Category members Pathway Pathway_234 PID_ENDOTHELIN_PATHWAY 0 0
Category members Pathway Pathway_40 KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_430 PID_TXA2PATHWAY 0 0
Category members Pathway Pathway_487 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 0 0
Category members Pathway Pathway_489 PID_NFAT_TFPATHWAY 0 0
Category members Pathway Pathway_618 REACTOME_DOWNSTREAM_TCR_SIGNALING 0 0
Category members Pathway Pathway_692 REACTOME_NETRIN1_SIGNALING 0 0
Category members Pathway Pathway_897 PID_CD8_TCR_DOWNSTREAM_PATHWAY 0 0
Category members GO Category GO:0001558 regulation of cell growth Database 0
Category members GO Category GO:0001772 immunological synapse Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0032740 positive regulation of interleukin-17 production Database 0
Category members GO Category GO:0032753 positive regulation of interleukin-4 production Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0045086 positive regulation of interleukin-2 biosynthetic process Database 0
Category members GO Category GO:0046627 negative regulation of insulin receptor signaling pathway Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051092 positive regulation of NF-kappaB transcription factor activity Database 0


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