RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
JUN	3	-0.930	0.930			-0.126
MAPK14	2	-0.160	-0.350
GNAI3	1	0.750	-0.890
GNAI3	1	0.750	-0.890	0.217			-0.334	-0.374
GNAO1	1	1.200	-1.320
GNAO1	1	1.200	-1.320	0.217			-0.334	-0.374
GNA11	1	2.030	-1.240	0.953			0.764	0.108
RAF1	1	2.020	-1.230
ADCY3	1	-0.850	1.180
MAP2K1	1	-1.590	2.780
PRKCH	0	1.450	-1.320
GNAI1	0	-0.580	0.990
GNAI2	0	0.190	-0.520
GNAL	0	1.660	-1.170
GNAS	0	0.840	-0.750
GNAT1	0	-0.110	-0.270
GNAT2	0	0.140	-0.880
GNAT3	0	1.110	-0.500
PRKCQ	0	0.410	0.020
RHOA	0	-0.510	1.370	-0.485			0.532	0.279
CDC42	0	-0.170	0.490	-0.597			-1.527	-1.013
CDC42	0	1.240	-0.940	-0.597			-1.527	-1.013
SLC9A1	0	1.000	-1.310
MAPK3	0
ADCY7	0
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
GNAI1	0	-0.580	0.990	0.116			-0.747
GNAZ	0	-0.020	-0.560
RAC1	0	-0.580	1.580	0.486			-0.364	-0.568
GNAL	0	1.660	-1.170
GNAL	0	1.660	-1.170	-0.166	-0.094	0.032	0.420	0.504
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
PRKCA	0	0.750	-0.690				0.349	0.585
PRKCA	0	0.750	-0.690
GNA14	0	1.610	-0.450					0.492
GNAQ	0	0.140	-0.310				0.052	0.449
ADCY9	0	-0.910	0.930
PRKCD	0	0.250	0.070				0.578	0.427
PRKCB	0	0.260	-0.530
PRKCB	0	0.260	-0.530				0.349	0.585
CRK	0	-0.790	0.230
ADCY6	0	-0.720	0.740
HRAS	0	1.470	-0.520
PLCB1	0	-0.300	-0.220
SRC	0	0.050	0.470	-0.031

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ADCY3	Ubiquitylation	K406	-0.885		_TK(gl)TGVDMR_
ADCY3	Ubiquitylation	K628		0.051	_YSVEK(gl)EK_
ADCY3	Ubiquitylation	K879	0.818	2.820	_IEVHDQK(gl)ER_
ADCY3	Ubiquitylation	K1047		-1.036	_IGMNK(gl)GGVLAGVIGAR_
ADCY6	Phosphorylation	S54	-1.434	-1.374	_DAEPPS(ph)PTPAGPPR_
ADCY6	Ubiquitylation	K80	0.473	0.937	_GK(gl)ELGLR_
ADCY6	Ubiquitylation	K568	1.007	0.799	_AMLAK(gl)LQR_
ADCY6	Phosphorylation	S576		-0.020	_ANS(ph)MEGLMPR_
ADCY7	Ubiquitylation	K477		0.660	_GDAALK(gl)MR_
ADCY9	Ubiquitylation	K35	0.400		_INPK(gl)QLSSNSHPK_
ADCY9	Ubiquitylation	K564	0.874	0.253	_LGQSVVADQLK(gl)GLK_
ADCY9	Ubiquitylation	K622	0.176	0.287	_GQGTASSGNVSDLAQTVK(gl)TFDNLK_
ADCY9	Ubiquitylation	K628	0.266		_TFDNLK(gl)TCPSCGITFAPK_
ADCY9	Ubiquitylation	K699		1.085	_LTNSQTSLCEILQEK(gl)GR_
ADCY9	Ubiquitylation	K1218	1.351	1.067	_VLSK(gl)MGYDFDYR_
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
CDC42	Ubiquitylation	K173	-1.839		_DDPSTIEK(gl)LAK_
CDC42	Ubiquitylation	K178	-0.801	-0.716	_NK(gl)QKPITPETAEK_
CDC42	Ubiquitylation	K180	-1.806		_QK(gl)PITPETAEK(gl)LAR_
CDC42	Ubiquitylation	K189	-1.082		_QKPITPETAEK(gl)LAR_
CDC42	Ubiquitylation	K198	0.550	1.159	_AVK(gl)YVECSALTQK_
CDC42	Ubiquitylation	K208	-0.937	0.038	_YVECSALTQK(gl)GLK_
CDC42	Ubiquitylation	K228	-2.488		_NVFDEAILAALEPPEPK(gl)K_
CDC42	Ubiquitylation	K229	-1.254		_NVFDEAILAALEPPEPKK(gl)_
CRK	Phosphorylation	S40	0.533	0.363	_DS(ph)STSPGDYVLSVSENSR_
CRK	Phosphorylation	S41	1.065	0.801	_DSS(ph)TSPGDYVLSVSENSR_
GNA11	Ubiquitylation	K16	0.347		_(ac)TLESMMACCLSDEVK(gl)ESKR_
GNA11	Ubiquitylation	K27	0.292	1.135	_RINAEIEK(gl)QLR_
GNA11	Ubiquitylation	K102	0.502	0.512	_ILYK(gl)YEQNK_
GNAI1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI1	Ubiquitylation	K92	0.873	0.567	_LK(gl)IDFGDSAR_
GNAI2	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI3	Ubiquitylation	K29	0.529	-0.094	_NLREDGEK(gl)AAK_
GNAI3	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI3	Ubiquitylation	K92	1.569		_LK(gl)IDFGEAAR_
GNAI3	Ubiquitylation	K349	-0.221	-0.339	_NNLK(gl)ECGLY_
GNAL	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAL	Ubiquitylation	K58	-1.182	0.161	_STIVK(gl)QM(ox)R_
GNAO1	Ubiquitylation	K29	0.529	-0.094	_NLREDGEK(gl)AAK_
GNAO1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAO1	Ubiquitylation	K92	1.569		_LK(gl)IDFGEAAR_
GNAO1	Ubiquitylation	K349	-0.221	-0.339	_NNLK(gl)ECGLY_
GNAQ	Ubiquitylation	K16	0.245		_TLESIMACCLSEEAK(gl)EAR_
GNAQ	Ubiquitylation	K102	-0.299		_IPYK(gl)YEHNK_
GNAS	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT2	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT3	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAZ	Ubiquitylation	K51	0.481	-0.051	_STIVK(gl)QMK_
GNAZ	Ubiquitylation	K189	0.945		_DMTTGIVENK(gl)FTFK_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
JUN	Phosphorylation	S58	-0.167	-1.247	_AKNS(ph)DLLTSPDVGLLK_
JUN	Phosphorylation	T62	2.545	1.674	_NSDLLT(ph)SPDVGLLK_
JUN	Phosphorylation	S63	2.030	1.458	_NSDLLTS(ph)PDVGLLK_
JUN	Ubiquitylation	K70	9.213		_NSDLLTSPDVGLLK(gl)_
JUN	Phosphorylation	S73	1.499	0.845	_LAS(ph)PELER_
JUN	Phosphorylation	S243	-0.642	-1.399	_LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN	Ubiquitylation	K309	1.034	0.155	_EQVAQLK(gl)QK_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAPK14	Phosphorylation	S2	3.221	3.623	_(ac)S(ph)QERPTFYR_
MAPK14	Phosphorylation	T180	0.958	1.087	_HTDDEM(ox)T(ph)GYVATR_
MAPK14	Phosphorylation	Y182	1.388	1.374	_HTDDEM(ox)TGY(ph)VATR_
MAPK14	Ubiquitylation	K249	0.073	-1.380	_LVGTPGAELLKK(gl)_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
PLCB1	Phosphorylation	S1199	-0.494		_TPS(ph)SEELGGDIPGKEFDTPL_
PLCB1	Phosphorylation	S1200		-0.483	_TPSS(ph)EELGGDIPGKEFDTPL_
PRKCA	Phosphorylation	S10	-0.650	0.036	_(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCA	Phosphorylation	S13	-1.038	0.335	_(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCA	Phosphorylation	S226	0.693	0.415	_STLNPQWNES(ph)FTFK_
PRKCA	Ubiquitylation	K316	-0.522	-0.535	_LGPAGNK(gl)VISPSEDR_
PRKCB	Phosphorylation	S10	-0.650	0.036	_(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCB	Phosphorylation	S13	-1.038	0.335	_(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCB	Phosphorylation	S226	0.693	0.415	_STLNPQWNES(ph)FTFK_
PRKCB	Ubiquitylation	K315	0.213	0.518	_ISQGTK(gl)VPEEK_
PRKCD	Ubiquitylation	K138	-0.141		_SEDEAK(gl)FPTMNR_
PRKCD	Ubiquitylation	K222	0.185	0.658	_DTIFQK(gl)ER_
PRKCD	Phosphorylation	S302	-0.240	-0.222	_S(ph)DSASSEPVGIYQGFEK_
PRKCD	Phosphorylation	S304	0.378	0.289	_RSDS(ph)ASSEPVGIYQGFEK_
PRKCD	Phosphorylation	S506	-0.213	0.200	_AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD	Phosphorylation	T507	-0.149	0.240	_AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD	Ubiquitylation	K641	-2.000		_DYSNFDQEFLNEK(gl)AR_
PRKCD	Phosphorylation	S645	0.577	0.832	_ARLS(ph)YSDK_
PRKCD	Phosphorylation	S647	0.886	0.853	_ARLSYS(ph)DK_
PRKCH	Ubiquitylation	K36	-0.644		_K(gl)GHQLLDPYLTVSVDQVR_
PRKCH	Ubiquitylation	K152	1.064		_IFK(gl)HFTR_
PRKCH	Phosphorylation	S317	-0.562	-0.534	_TLAGMGLQPGNIS(ph)PTSK_
PRKCH	Phosphorylation	T656	-0.471		_SREDVSNFDPDFIKEEPVLT(ph)PIDEGHLPM(ox)INQDEFR_
PRKCQ	Phosphorylation	S685		0.911	_ALINS(ph)MDQNMFR_
RAC1	Ubiquitylation	K115	-1.745	-0.215	_AK(gl)WYPEVR_
RAC1	Ubiquitylation	K142	0.492		_LDLRDDK(gl)DTIEK_
RAC1	Ubiquitylation	K152	0.099	-0.292	_K(gl)LTPITYPQGLAMAK_
RAC1	Ubiquitylation	K166	-0.981	-0.655	_LTPITYPQGLAMAK(gl)EIGAVK_
RAC1	Ubiquitylation	K172	1.026	0.412	_EIGAVK(gl)YLECSALTQR_
RAC1	Ubiquitylation	K185	-0.113	0.578	_GLK(gl)TVFDEAIR_
RAC1	Ubiquitylation	K202	-1.379	-1.447	_AVLCPPPVK(gl)KR_
RAC1	Ubiquitylation	K203	-1.708	-1.447	_AVLCPPPVKK(gl)_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
RHOA	Ubiquitylation	K6	0.708		_K(gl)KLVIVGDGACGK_
RHOA	Ubiquitylation	K7	0.708		_K(gl)KLVIVGDGACGK_
RHOA	Ubiquitylation	K118	-0.408		_HFCPNVPIILVGNK(gl)K_
RHOA	Ubiquitylation	K119	-0.408		_HFCPNVPIILVGNK(gl)K_
RHOA	Ubiquitylation	K135	-0.528	-0.796	_MK(gl)QEPVKPEEGRDMANR_
RHOA	Ubiquitylation	K162	0.345	0.453	_IGAFGYMECSAK(gl)TK_
SLC9A1	Phosphorylation	S693	0.458	0.404	_INNYLTVPAHKLDS(ph)PTM(ox)SR_
SLC9A1	Phosphorylation	S703	-0.097	0.010	_IGS(ph)DPLAYEPK_
SLC9A1	Phosphorylation	S785	-0.871	-0.971	_ETSSPGTDDVFTPAPSDS(ph)PSSQR_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_