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Query: PRKCH

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRKCH 0 0.059 1.450 -1.320

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRKCH Phosphorylation S317 -0.562 -0.534 _TLAGMGLQPGNIS(ph)PTSK_
PRKCH Ubiquitylation K36 -0.644 _K(gl)GHQLLDPYLTVSVDQVR_
PRKCH Ubiquitylation K152 1.064 _IFK(gl)HFTR_
PRKCH Phosphorylation T656 -0.471 _SREDVSNFDPDFIKEEPVLT(ph)PIDEGHLPM(ox)INQDEFR_

Background Information for PRKCH:


Pubmed-PRKCH »
Uniprot-PRKCH »
Biogrid-PRKCH »
ProteomicsDB-PRKCH »

Tumorportal-PRKCH »
COSMIC-PRKCH »
GenomeRNAi-PRKCH »
Genecards-PRKCH


Protein-protein Interactions for PRKCH
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PRKCA Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRKCH
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PE/DAG-bd IPR002219 0.63
Category members DAG/PE-bd IPR020454 0.18
Category members Kinase-like_dom IPR011009 0.03
Category members C2_dom IPR000008 0
Category members Prot_kinase_dom IPR000719 0
Category members AGC-kinase_C IPR000961 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Prot_kin_PKC_delta IPR014376 0
Category members Pkinase_C IPR017892 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring PRKCH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRKCH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members Pathway Pathway_1023 PID_NFAT_3PATHWAY 0 1.46
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Pathway Pathway_228 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS 0 0.24
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_485 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS 0 0.18
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members Pathway Pathway_56 REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 0 0.11
Category members GO Category GO:0004697 protein kinase C activity Database 0.09
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members Pathway Pathway_486 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 0 0.04
Category members GO Category GO:0034351 negative regulation of glial cell apoptotic process Database 0.01
Category members Pathway Pathway_160 KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION 0 0.01
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0010744 positive regulation of macrophage derived foam cell differentiation Database 0
Category members Pathway Pathway_1048 BIOCARTA_KERATINOCYTE_PATHWAY 0 0
Category members Pathway Pathway_234 PID_ENDOTHELIN_PATHWAY 0 0
Category members Pathway Pathway_430 PID_TXA2PATHWAY 0 0
Category members Pathway Pathway_487 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 0 0
Category members Disease phenotype STROKE_ISCHEMIC STROKE ISCHEMIC Database 0
Category members GO Category GO:0004699 calcium-independent protein kinase C activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0017160 Ral GTPase binding Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0045618 positive regulation of keratinocyte differentiation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0050861 positive regulation of B cell receptor signaling pathway Database 0
Category members GO Category GO:0051092 positive regulation of NF-kappaB transcription factor activity Database 0
Category members GO Category GO:0060252 positive regulation of glial cell proliferation Database 0
Category members GO Category GO:0070528 protein kinase C signaling Database 0


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