Results for the Category
positive regulation of T cell activation
(GO:0050870)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| TRAF2 | 1 | -0.570 | 0.540 | |||||
| TRAF2 | 1 | -0.570 | 0.540 | |||||
| BCL10 | 1 | 0.000 | 0.200 | |||||
| PRKCQ | 0 | 0.410 | 0.020 | |||||
| CORO1A | 0 | 0.430 | 0.570 | -0.555 | -0.197 | -0.725 | ||
| MAP3K7 | 0 | -1.120 | 1.140 | -1.048 | ||||
| HSPD1 | 0 | 1.020 | -0.650 | 1.151 | 0.719 | -0.757 | ||
| LCK | 0 | -0.490 | 1.390 | 0.295 | 0.576 | |||
| CD47 | 0 | 0.860 | -0.750 | 0.968 | 0.864 | |||
| ADA | 0 | 0.340 | -0.830 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ADA | Ubiquitylation | K312 | 0.123 | _STLDTDYQMTK(gl)R_ | |
| BCL10 | Phosphorylation | S138 | 1.515 | 1.393 | _SNS(ph)DESNFSEK_ |
| CD47 | Ubiquitylation | K317 | 0.065 | _AVEEPLNAFKESK(gl)_ | |
| HSPD1 | Phosphorylation | S70 | 0.210 | 0.487 | _TVIIEQSWGS(ph)PK_ |
| HSPD1 | Ubiquitylation | K82 | -0.300 | _DGVTVAK(gl)SIDLK_ | |
| HSPD1 | Ubiquitylation | K87 | -0.005 | 0.292 | _SIDLK(gl)DKYK_ |
| HSPD1 | Ubiquitylation | K130 | -0.428 | _EGFEK(gl)ISK_ | |
| HSPD1 | Ubiquitylation | K233 | 0.853 | 0.024 | _GYISPYFINTSK(gl)GQK_ |
| HSPD1 | Ubiquitylation | K292 | 0.339 | _LK(gl)VGLQVVAVK_ | |
| LCK | Phosphorylation | T37 | -0.435 | _YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_ | |
| LCK | Ubiquitylation | K191 | -0.112 | 0.264 | _ESETTK(gl)GAYSLSIR_ |
| LCK | Ubiquitylation | K235 | 0.323 | _AQFDTLQK(gl)LVK_ | |
| LCK | Ubiquitylation | K259 | -1.613 | _LTTVCPTVK(gl)PQTQGLAK_ | |
| MAP3K7 | Phosphorylation | S374 | 0.149 | -0.337 | _GS(ph)SVESLPPTSEGK_ |
| MAP3K7 | Phosphorylation | S375 | 0.171 | -0.087 | _GSS(ph)VESLPPTSEGK_ |
| MAP3K7 | Phosphorylation | S389 | 1.072 | 1.445 | _RMS(ph)ADMSEIEAR_ |
| MAP3K7 | Phosphorylation | S439 | 0.246 | 0.198 | _S(ph)IQDLTVTGTEPGQVSSR_ |
| MAP3K7 | Ubiquitylation | K474 | -0.385 | -0.242 | _MITTSGPTSEK(gl)PTR_ |
| MAP3K7 | Ubiquitylation | K589 | -0.104 | _SLSTYYQQCK(gl)K_ | |
| MAP3K7 | Ubiquitylation | K590 | -0.551 | 0.560 | _K(gl)QLEVIR_ |
| PRKCQ | Phosphorylation | S685 | 0.911 | _ALINS(ph)MDQNMFR_ | |
| TRAF2 | Phosphorylation | T7 | -0.822 | -1.190 | _(ac)AAASVT(ph)PPGSLELLQPGFSK_ |
| TRAF2 | Ubiquitylation | K27 | -0.253 | 2.194 | _TLLGTK(gl)LEAK_ |
| TRAF2 | Ubiquitylation | K119 | 0.519 | _GTLK(gl)EYESCHEGR_ | |
| TRAF2 | Ubiquitylation | K176 | -1.233 | 1.022 | _APCCGADVK(gl)AHHEVCPK_ |
| TRAF2 | Ubiquitylation | K207 | 0.147 | 0.918 | _FQDHVK(gl)TCGK_ |
| TRAF2 | Ubiquitylation | K481 | -0.507 | 0.417 | _MEAK(gl)NSYVR_ |
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