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Query: DGKE

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DGKE 0 1.562 -0.800 1.500 -0.239 0.518

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DGKE Ubiquitylation K357 -0.396 0.179 _VQVTNK(gl)GYYNLR_
DGKE Ubiquitylation K212 -0.965 _TDYEVLASK(gl)LGK_

Background Information for DGKE:


Pubmed-DGKE »
Uniprot-DGKE »
Biogrid-DGKE »
ProteomicsDB-DGKE »

Tumorportal-DGKE »
COSMIC-DGKE »
GenomeRNAi-DGKE »
Genecards-DGKE


Protein-protein Interactions for DGKE
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in DGKE
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PE/DAG-bd IPR002219 0.63
Category members Diacylglycerol_kin_accessory IPR000756 0
Category members Diacylglycerol_kinase_cat_dom IPR001206 0


Protein complexes (CORUM database) featuring DGKE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DGKE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_71 KEGG_GLYCEROLIPID_METABOLISM 0 0.45
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway Database 0.36
Category members Pathway Pathway_485 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS 0 0.18
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members Pathway Pathway_56 REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 0 0.11
Category members Pathway Pathway_486 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 0 0.04
Category members GO Category GO:0004143 diacylglycerol kinase activity Database 0.03
Category members Pathway Pathway_276 KEGG_GLYCEROPHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_487 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 0 0
Category members Pathway Pathway_488 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 0 0
Category members Disease phenotype Immunoglobulin-mediated_membranoproliferative_glomerulonephritis Immunoglobulin-mediated membranoproliferative glomerulonephritis Database 0
Category members GO Category GO:0003951 NAD+ kinase activity Database 0
Category members GO Category GO:0008654 phospholipid biosynthetic process Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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