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Query: ANXA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ANXA1 1 -3.631 1.050 -0.850 1.883

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ANXA1:


Pubmed-ANXA1 »
Uniprot-ANXA1 »
Biogrid-ANXA1 »
ProteomicsDB-ANXA1 »

Tumorportal-ANXA1 »
COSMIC-ANXA1 »
GenomeRNAi-ANXA1 »
Genecards-ANXA1


Protein-protein Interactions for ANXA1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANXA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC88A Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF11 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPIA Cat. description Hein, Mann, Cell 2015
Category members IP bait TFG Cat. description Hein, Mann, Cell 2015
Category members IP bait DDX19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FRMD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIR2DS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPUSD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ANXA1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Annexin IPR001464 0.13
Category members Annexin_repeat IPR018502 0.13


Protein complexes (CORUM database) featuring ANXA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ANXA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0043234 protein complex Database 2.73
Category members Pathway Pathway_1105 REACTOME_GPCR_LIGAND_BINDING 0 2.35
Category members Pathway Pathway_1182 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 0 1.69
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0018149 peptide cross-linking Database 0.62
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members Pathway Pathway_1186 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 0 0.54
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members Pathway Pathway_263 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 0 0.49
Category members GO Category GO:0042383 sarcolemma Database 0.36
Category members GO Category GO:0010165 response to X-ray Database 0.32
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0030674 protein binding, bridging Database 0.25
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members GO Category GO:0060206 estrous cycle phase Database 0.23
Category members GO Category GO:0004859 phospholipase inhibitor activity Database 0.23
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members GO Category GO:0042063 gliogenesis Database 0.1
Category members GO Category GO:0001533 cornified envelope Database 0.09
Category members GO Category GO:0042127 regulation of cell proliferation Database 0.06
Category members GO Category GO:0050709 negative regulation of protein secretion Database 0.06
Category members GO Category GO:0051384 response to glucocorticoid Database 0.04
Category members Pathway Pathway_486 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 0 0.04
Category members GO Category GO:0016323 basolateral plasma membrane Database 0.04
Category members GO Category GO:0070365 hepatocyte differentiation Database 0.03
Category members GO Category GO:0070555 response to interleukin-1 Database 0.02
Category members GO Category GO:0009725 response to hormone Database 0.01
Category members GO Category GO:0070301 cellular response to hydrogen peroxide Database 0
Category members Pathway Pathway_439 BIOCARTA_GCR_PATHWAY 0 0
Category members Pathway Pathway_487 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 0 0
Category members GO Category GO:0001780 neutrophil homeostasis Database 0
Category members GO Category GO:0002674 negative regulation of acute inflammatory response Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005543 phospholipid binding Database 0
Category members GO Category GO:0005544 calcium-dependent phospholipid binding Database 0
Category members GO Category GO:0005929 cilium Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0014070 response to organic cyclic compound Database 0
Category members GO Category GO:0019834 phospholipase A2 inhibitor activity Database 0
Category members GO Category GO:0030073 insulin secretion Database 0
Category members GO Category GO:0030216 keratinocyte differentiation Database 0
Category members GO Category GO:0031018 endocrine pancreas development Database 0
Category members GO Category GO:0031340 positive regulation of vesicle fusion Database 0
Category members GO Category GO:0031394 positive regulation of prostaglandin biosynthetic process Database 0
Category members GO Category GO:0031960 response to corticosteroid Database 0
Category members GO Category GO:0031966 mitochondrial membrane Database 0
Category members GO Category GO:0032355 response to estradiol Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043434 response to peptide hormone Database 0
Category members GO Category GO:0046632 alpha-beta T cell differentiation Database 0
Category members GO Category GO:0050482 arachidonic acid secretion Database 0
Category members GO Category GO:0071385 cellular response to glucocorticoid stimulus Database 0


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