bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »
bioLOGIC Category

Results for the Category
positive regulation of ERK1 and ERK2 cascade
(GO:0070374)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RIPK2 1 -1.740 3.580
ARRB2 1 2.000 -1.160 -0.340 0.096 0.051 -1.604
S100A7 1 0.370 -0.020 -3.874
S100A7 1 2.090 -1.290 -3.874
PDGFA 1 0.190 -0.340 -2.109 1.885
CD44 0 0.270 -0.230
FLT4 0 0.940 -0.560
PRKCZ 0 -0.290 0.310
FGFR3 0 -1.120 1.390
MAPK3 0
PRKD2 0 0.050 0.170 0.914
PRKD2 0 0.050 0.170
RAPGEF2 0 -0.860 1.560
HMGCR 0 0.240 0.010
KDR 0 0.860 -0.680
ARRB1 0 0.960 -0.620
EGFR 0 -0.580 0.520 0.513 0.090
PRKCA 0 0.750 -0.690 0.349 0.585
PRKCA 0 0.750 -0.690
BRAF 0
F2RL1 0 -1.330 2.490
HRAS 0 1.470 -0.520
ERBB4 0
ERBB4 0
F2R 0 0.220 0.110
GAS6 0 0.020 0.220 -1.517 -0.502
SRC 0 0.050 0.470 -0.031
MIF 0 1.480 -0.910 -0.887 -0.872 -1.709 0.653
ARHGAP8 0 1.770 -1.250

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ARHGAP8 Phosphorylation S34 -0.311 0.097 _FM(ox)S(ph)SPSLSDLGK_
ARRB1 Phosphorylation S412 0.138 0.253 _GMKDDKEEEEDGTGS(ph)PQLNNR_
ARRB2 Ubiquitylation K199 -1.933 _VQFAPEK(gl)PGPQPSAETTR_
BRAF Phosphorylation S151 -0.685 -0.629 _SNPKS(ph)PQKPIVR_
BRAF Phosphorylation S363 -0.023 -0.241 _S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF Phosphorylation S365 -0.286 0.012 _SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF Phosphorylation S399 -0.890 -0.527 _GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF Phosphorylation T401 -0.525 _GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF Phosphorylation S446 0.246 0.349 _RDS(ph)SDDWEIPDGQITVGQR_
BRAF Phosphorylation S447 0.579 0.623 _RDSS(ph)DDWEIPDGQITVGQR_
BRAF Phosphorylation S729 0.208 0.219 _SAS(ph)EPSLNR_
CD44 Ubiquitylation K739 -0.024 0.134 _NLQNVDMK(gl)IGV_
EGFR Phosphorylation T693 0.486 -0.139 _ELVEPLT(ph)PSGEAPNQALLR_
EGFR Phosphorylation S991 -0.041 _MHLPS(ph)PTDSNFYR_
ERBB4 Ubiquitylation K714 0.078 _ILK(gl)ETELKR_
ERBB4 Ubiquitylation K745 -0.474 0.342 _GIWVPEGETVK(gl)IPVAIK_
ERBB4 Ubiquitylation K854 -0.859 _NVLVK(gl)SPNHVK_
F2R Ubiquitylation K421 0.836 0.568 _MDTCSSNLNNSIYK(gl)K_
F2RL1 Ubiquitylation K368 0.159 0.737 _TVK(gl)QMQVSLTSK_
F2RL1 Ubiquitylation K377 -0.040 -0.268 _QMQVSLTSK(gl)K_
F2RL1 Ubiquitylation K378 0.066 -0.268 _QMQVSLTSKK(gl)_
F2RL1 Phosphorylation S384 0.573 1.068 _KSS(ph)SYSSSSTTVK_
F2RL1 Ubiquitylation K394 0.350 0.873 _KSSSYSSSSTTVK(gl)TSY_
FGFR3 Ubiquitylation K205 -0.115 _IGGIK(gl)LR_
FLT4 Ubiquitylation K987 -0.270 _FSK(gl)TEGGAR_
FLT4 Ubiquitylation K1064 -1.119 _DIYK(gl)DPDYVR_
HMGCR Ubiquitylation K142 -0.522 _ASTLAK(gl)FALSSNSQDEVR_
HMGCR Ubiquitylation K248 -3.854 -2.107 _VLEEEENK(gl)PNPVTQR_
HMGCR Ubiquitylation K299 -1.680 -0.460 _VSLGLDENVSK(gl)R_
HMGCR Ubiquitylation K363 -1.750 _NPITSPVVTQKK(gl)_
HMGCR Ubiquitylation K381 -0.848 _NNQK(gl)CDSVEEETGINR_
HMGCR Ubiquitylation K401 -3.050 _KVEVIK(gl)PLVAETDTPNR_
HMGCR Ubiquitylation K502 -1.382 _K(gl)LSEPSSLQYLPYR_
HMGCR Ubiquitylation K633 -1.104 _LQK(gl)LHTSIAGR_
HMGCR Ubiquitylation K662 -1.291 _SGDAMGMNMISK(gl)GTEK_
HMGCR Ubiquitylation K704 -1.716 _GK(gl)SVVCEAVIPAK(gl)VVR_
HMGCR Ubiquitylation K715 -1.982 _SVVCEAVIPAK(gl)VVR_
HMGCR Ubiquitylation K873 -1.345 _SK(gl)INLQDLQGACTKK_
HMGCR Ubiquitylation K885 -1.690 _SKINLQDLQGACTK(gl)K_
HMGCR Ubiquitylation K886 -1.325 _INLQDLQGACTKK(gl)_
HRAS Ubiquitylation K170 -1.005 _K(gl)LNPPDESGPGCMSCK_
KDR Ubiquitylation K1064 -1.119 _DIYK(gl)DPDYVR_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
MIF Ubiquitylation K78 0.018 0.329 _SYSK(gl)LLCGLLAER_
PRKCA Phosphorylation S10 -0.650 0.036 _(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCA Phosphorylation S13 -1.038 0.335 _(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCA Phosphorylation S226 0.693 0.415 _STLNPQWNES(ph)FTFK_
PRKCA Ubiquitylation K316 -0.522 -0.535 _LGPAGNK(gl)VISPSEDR_
PRKCZ Phosphorylation T560 -0.884 -1.578 _KQALPPFQPQITDDYGLDNFDTQFTSEPVQLT(ph)PDDEDAIKR_
PRKD2 Phosphorylation S197 0.239 0.895 _RLS(ph)STSLASGHSVR_
PRKD2 Phosphorylation T211 -0.119 _LGT(ph)SESLPCTAEELSR_
PRKD2 Phosphorylation S212 0.113 _LGTS(ph)ESLPCTAEELSR_
PRKD2 Phosphorylation S214 0.216 0.302 _LGTSES(ph)LPCTAEELSR_
PRKD2 Phosphorylation S710 -0.413 -0.511 _S(ph)VVGTPAYLAPEVLLNQGYNR_
PRKD2 Phosphorylation T714 -0.279 _S(ph)VVGTPAYLAPEVLLNQGYNR_
PRKD2 Ubiquitylation K730 1.177 _IIGEK(gl)SFR_
PRKD2 Phosphorylation S886 -0.718 -0.305 _DLGGACPPQDHDMQGLAERIS(ph)VL_
RAPGEF2 Phosphorylation S1022 0.043 -0.570 _SETS(ph)PVAPR_
RAPGEF2 Phosphorylation S1080 -0.612 _DLPPFGINS(ph)PQALK_
RIPK2 Ubiquitylation K410 -2.810 _AAFCDHK(gl)TTPCSSAIINPLSTAGNSER_
RIPK2 Phosphorylation S531 0.884 0.839 _SPS(ph)LNLLQNK_
RIPK2 Ubiquitylation K538 -2.659 _SPSLNLLQNK(gl)SM_
SRC Phosphorylation S17 -0.604 -0.689 _S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC Phosphorylation S75 0.060 0.331 _LFGGFNSSDTVTS(ph)PQR_


© Copyright Svejstrup Laboratory 2015