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Query: ARHGAP8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARHGAP8 0 -0.214 1.770 -1.250

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARHGAP8 Phosphorylation S34 -0.311 0.097 _FM(ox)S(ph)SPSLSDLGK_

Background Information for ARHGAP8:


Pubmed-ARHGAP8 »
Uniprot-ARHGAP8 »
Biogrid-ARHGAP8 »
ProteomicsDB-ARHGAP8 »

Tumorportal-ARHGAP8 »
COSMIC-ARHGAP8 »
GenomeRNAi-ARHGAP8 »
Genecards-ARHGAP8


Protein-protein Interactions for ARHGAP8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARHGAP8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ISOC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARHGAP8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rho_GTPase_activation_prot IPR008936 0.53
Category members RhoGAP_dom IPR000198 0
Category members CRAL-TRIO_dom IPR001251 0


Protein complexes (CORUM database) featuring ARHGAP8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2029 BNIP2-ARHGAP8 complex Database 0


Categories featuring ARHGAP8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0070374 positive regulation of ERK1 and ERK2 cascade Database 0.65
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_1172 PID_RHOA_REG_PATHWAY 0 0.09
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members GO Category GO:0005100 Rho GTPase activator activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0032321 positive regulation of Rho GTPase activity Database 0


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