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Query: CD44

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CD44 0 0.109 0.270 -0.230

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CD44 Ubiquitylation K739 -0.024 0.134 _NLQNVDMK(gl)IGV_

Background Information for CD44:


Pubmed-CD44 »
Uniprot-CD44 »
Biogrid-CD44 »
ProteomicsDB-CD44 »

Tumorportal-CD44 »
COSMIC-CD44 »
GenomeRNAi-CD44 »
Genecards-CD44


Protein-protein Interactions for CD44
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD44 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CD44
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members C-type_lectin_fold IPR016187 0.01
Category members Link IPR000538 0


Protein complexes (CORUM database) featuring CD44
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CD44
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_73 REACTOME_GLYCOSAMINOGLYCAN_METABOLISM 0 1.71
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0030203 glycosaminoglycan metabolic process Database 1.44
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0070374 positive regulation of ERK1 and ERK2 cascade Database 0.65
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members Pathway Pathway_449 KEGG_HEMATOPOIETIC_CELL_LINEAGE 0 0.31
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0004888 transmembrane signaling receptor activity Database 0.15
Category members GO Category GO:0034116 positive regulation of heterotypic cell-cell adhesion Database 0.13
Category members GO Category GO:0004415 hyalurononglucosaminidase activity Database 0.11
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members Pathway Pathway_78 REACTOME_HYALURONAN_METABOLISM 0 0.1
Category members GO Category GO:0030212 hyaluronan metabolic process Database 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0070487 monocyte aggregation Database 0.04
Category members Pathway Pathway_80 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION 0 0.04
Category members GO Category GO:0016323 basolateral plasma membrane Database 0.04
Category members GO Category GO:0033138 positive regulation of peptidyl-serine phosphorylation Database 0.03
Category members GO Category GO:0005518 collagen binding Database 0.02
Category members GO Category GO:0009897 external side of plasma membrane Database 0
Category members Pathway Pathway_1127 SA_MMP_CYTOKINE_CONNECTION 0 0
Category members Pathway Pathway_1285 BIOCARTA_MONOCYTE_PATHWAY 0 0
Category members Pathway Pathway_564 PID_AVB3_OPN_PATHWAY 0 0
Category members Pathway Pathway_898 REACTOME_INTERFERON_GAMMA_SIGNALING 0 0
Category members Pathway Pathway_922 KEGG_ECM_RECEPTOR_INTERACTION 0 0
Category members GO Category GO:0001658 branching involved in ureteric bud morphogenesis Database 0
Category members GO Category GO:0002246 wound healing involved in inflammatory response Database 0
Category members GO Category GO:0005540 hyaluronic acid binding Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007160 cell-matrix adhesion Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0030214 hyaluronan catabolic process Database 0
Category members GO Category GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator Database 0
Category members GO Category GO:0044344 cellular response to fibroblast growth factor stimulus Database 0
Category members GO Category GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0051216 cartilage development Database 0
Category members GO Category GO:0060333 interferon-gamma-mediated signaling pathway Database 0
Category members GO Category GO:0060442 branching involved in prostate gland morphogenesis Database 0


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