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Query: FIS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FIS1 0 1.122 0.310 -0.460 -0.182 -0.304

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FIS1 Ubiquitylation K25 0.414 0.808 _FQSEK(gl)AAGSVSK_
FIS1 Ubiquitylation K46 0.800 0.340 _SK(gl)YNDDIRK_
FIS1 Ubiquitylation K108 -0.706 _GLLQTEPQNNQAK(gl)ELER_

Background Information for FIS1:


Pubmed-FIS1 »
Uniprot-FIS1 »
Biogrid-FIS1 »
ProteomicsDB-FIS1 »

Tumorportal-FIS1 »
COSMIC-FIS1 »
GenomeRNAi-FIS1 »
Genecards-FIS1


Protein-protein Interactions for FIS1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in FIS1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring FIS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 4200 DLP1-hFIS1 complex Database 0


Categories featuring FIS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0016559 peroxisome fission Database 0.54
Category members GO Category GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration Database 0.3
Category members GO Category GO:0008053 mitochondrial fusion Database 0.27
Category members GO Category GO:0031307 integral to mitochondrial outer membrane Database 0.24
Category members GO Category GO:0001836 release of cytochrome c from mitochondria Database 0.18
Category members GO Category GO:0006626 protein targeting to mitochondrion Database 0.11
Category members GO Category GO:0000422 mitochondrion degradation Database 0.1
Category members GO Category GO:0010821 regulation of mitochondrion organization Database 0.04
Category members GO Category GO:0000266 mitochondrial fission Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0005779 integral to peroxisomal membrane Database 0
Category members GO Category GO:0007204 positive regulation of cytosolic calcium ion concentration Database 0
Category members GO Category GO:0035584 calcium-mediated signaling using intracellular calcium source Database 0
Category members GO Category GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0043653 mitochondrial fragmentation involved in apoptotic process Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0
Category members GO Category GO:0051561 positive regulation of mitochondrial calcium ion concentration Database 0
Category members GO Category GO:0070584 mitochondrion morphogenesis Database 0


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