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Young adult-onset Parkinsonism
(Young_adult-onset_Parkinsonism)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
EIF4G1 1 -1.660 2.810 0.765
EIF4G1 1 -1.660 2.810 -0.451 -0.932 -0.258 -0.331
GBA 1 -1.380 2.580 0.407 0.357 0.150
VPS35 0 -0.480 0.040
VPS35 0 -0.480 0.040 -0.214 0.370 -0.544 0.601 0.416
HTRA2 0 1.220 -0.530 0.602 -0.023 1.287
PARK7 0 -0.660 0.930
DNAJC13 0 1.510 -1.180 -0.175 0.610 0.588
UCHL1 0 -0.500 0.500 1.153 -0.238
UCHL1 0 -0.500 0.500 0.687
LRRK2 0 0.530 -0.620 -0.240
GIGYF2 0 -0.660 0.630
GIGYF2 0 -0.660 0.630 -0.833 -0.034 -0.175

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
DNAJC13 Ubiquitylation K969 0.787 _ATVPLQSNVIEAAPDMK(gl)R_
EIF4G1 Ubiquitylation K627 -0.658 _SDQWK(gl)PLNLEEK_
EIF4G1 Ubiquitylation K635 -1.721 -1.834 _SDQWKPLNLEEKK(gl)_
EIF4G1 Phosphorylation T672 -1.605 _ANKT(ph)PLRPLDPTR_
EIF4G1 Ubiquitylation K925 0.326 _SLGNIK(gl)FIGELFK_
EIF4G1 Ubiquitylation K975 -0.759 _DLDFEK(gl)AKPR_
EIF4G1 Phosphorylation T1098 -0.123 _IT(ph)KPGSIDSNNQLFAPGGR_
EIF4G1 Phosphorylation S1102 0.238 -0.562 _ITKPGS(ph)IDSNNQLFAPGGR_
EIF4G1 Phosphorylation S1117 -0.554 _ITKPGSIDSNNQLFAPGGRLS(ph)WGK_
EIF4G1 Phosphorylation S1210 0.417 1.061 _S(ph)FSKEVEER_
EIF4G1 Phosphorylation S1212 1.007 0.725 _RSFS(ph)KEVEER_
EIF4G1 Phosphorylation S1234 0.676 1.054 _AAS(ph)LTEDRDR_
EIF4G1 Phosphorylation T1236 1.002 _KAAS(ph)LTEDRDR_
EIF4G1 Phosphorylation S1256 -1.072 -0.563 _REAALPPVS(ph)PLK_
EIF4G1 Phosphorylation S1263 0.713 0.836 _AALS(ph)EEELEKK_
GIGYF2 Phosphorylation S20 1.394 0.572 _ALSS(ph)GGSITS(ph)PPLSPALPK_
GIGYF2 Phosphorylation T25 -1.198 -0.724 _ALSSGGSIT(ph)SPPLSPALPK_
GIGYF2 Phosphorylation S26 -1.157 -0.630 _ALSSGGSITS(ph)PPLSPALPK_
GIGYF2 Phosphorylation S30 -1.557 -1.373 _ALSSGGSITS(ph)PPLS(ph)PALPK_
GIGYF2 Phosphorylation T404 -0.311 -0.134 _PGT(ph)PSDHQSQEASQFER_
GIGYF2 Ubiquitylation K1007 0.724 -1.404 _ALQQQQQQQQQK(gl)LSGWGNVSKPSGTTK_
GIGYF2 Ubiquitylation K1016 -0.562 _LSGWGNVSK(gl)PSGTTK_
GIGYF2 Ubiquitylation K1106 0.994 _NSNMGFWDDAVK(gl)EVGPR_
GIGYF2 Ubiquitylation K1125 0.915 -0.414 _NNASLSK(gl)SVGVSNR_
HTRA2 Ubiquitylation K237 -1.868 -0.270 _IQTK(gl)EPLPTLPLGR_
PARK7 Ubiquitylation K41 0.222 0.590 _VTVAGLAGK(gl)DPVQCSR_
PARK7 Ubiquitylation K93 -0.291 _EILK(gl)EQENR_
PARK7 Ubiquitylation K132 0.639 _VTTHPLAKDK(gl)_
UCHL1 Ubiquitylation K4 -0.164 -0.657 _MQLK(gl)PMEINPEMLNK_
UCHL1 Ubiquitylation K65 -0.004 -0.789 _K(gl)QIEELKGQEVSPK_
UCHL1 Ubiquitylation K71 -0.121 -0.325 _QIEELK(gl)GQEVSPK_
UCHL1 Ubiquitylation K78 -0.595 _QIEELKGQEVSPK(gl)VYFMK_
UCHL1 Ubiquitylation K123 -0.013 -0.297 _QFLSETEK(gl)M(ox)SPEDR_
UCHL1 Ubiquitylation K135 -0.048 _CFEK(gl)NEAIQAAHDAVAQEGQCR_
UCHL1 Ubiquitylation K195 -0.285 -0.704 _MPFPVNHGASSEDTLLK(gl)DAAK_
UCHL1 Ubiquitylation K221 -0.155 -0.216 _FSAVALCK(gl)AA_
VPS35 Phosphorylation T4 -0.120 _PTT(ph)QQSPQDEQEKLLDEAIQAVK_
VPS35 Phosphorylation S7 0.322 _PTTQQS(ph)PQDEQEKLLDEAIQAVK_
VPS35 Ubiquitylation K659 -0.478 _TQCALAASK(gl)LLK_


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