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Query: GIGYF2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GIGYF2 0 2.134 -0.660 0.630
GIGYF2 0 2.134 -0.660 0.630 -0.833 -0.034 -0.175

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GIGYF2 Phosphorylation S20 1.394 0.572 _ALSS(ph)GGSITS(ph)PPLSPALPK_
GIGYF2 Phosphorylation T404 -0.311 -0.134 _PGT(ph)PSDHQSQEASQFER_
GIGYF2 Ubiquitylation K1125 0.915 -0.414 _NNASLSK(gl)SVGVSNR_
GIGYF2 Ubiquitylation K1016 -0.562 _LSGWGNVSK(gl)PSGTTK_
GIGYF2 Phosphorylation S26 -1.157 -0.630 _ALSSGGSITS(ph)PPLSPALPK_
GIGYF2 Phosphorylation T25 -1.198 -0.724 _ALSSGGSIT(ph)SPPLSPALPK_
GIGYF2 Phosphorylation S30 -1.557 -1.373 _ALSSGGSITS(ph)PPLS(ph)PALPK_
GIGYF2 Ubiquitylation K1007 0.724 -1.404 _ALQQQQQQQQQK(gl)LSGWGNVSKPSGTTK_
GIGYF2 Ubiquitylation K1106 0.994 _NSNMGFWDDAVK(gl)EVGPR_

Background Information for GIGYF2:


Pubmed-GIGYF2 »
Uniprot-GIGYF2 »
Biogrid-GIGYF2 »
ProteomicsDB-GIGYF2 »

Tumorportal-GIGYF2 »
COSMIC-GIGYF2 »
GenomeRNAi-GIGYF2 »
Genecards-GIGYF2


Protein-protein Interactions for GIGYF2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DIS3L Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait PARG Cat. description Hein, Mann, Cell 2015
Category members IP bait RFX5 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait C10orf88 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF4E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCAPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GIGYF2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members GYF IPR003169 0.11


Protein complexes (CORUM database) featuring GIGYF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GIGYF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0017148 negative regulation of translation Database 0.34
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0031571 mitotic G1 DNA damage checkpoint Database 0.08
Category members GO Category GO:0007631 feeding behavior Database 0.07
Category members GO Category GO:0048009 insulin-like growth factor receptor signaling pathway Database 0.04
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members GO Category GO:0048873 homeostasis of number of cells within a tissue Database 0.04
Category members GO Category GO:0050885 neuromuscular process controlling balance Database 0.02
Category members Disease phenotype Young_adult-onset_Parkinsonism Young adult-onset Parkinsonism Database 0
Category members GO Category GO:0008344 adult locomotory behavior Database 0
Category members GO Category GO:0009791 post-embryonic development Database 0
Category members GO Category GO:0021522 spinal cord motor neuron differentiation Database 0
Category members GO Category GO:0050881 musculoskeletal movement Database 0


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