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Query: UCHL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UCHL1 0 1.882 -0.500 0.500 1.153 -0.238
UCHL1 0 1.882 -0.500 0.500 0.687

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UCHL1 Ubiquitylation K221 -0.155 -0.216 _FSAVALCK(gl)AA_
UCHL1 Ubiquitylation K123 -0.013 -0.297 _QFLSETEK(gl)M(ox)SPEDR_
UCHL1 Ubiquitylation K71 -0.121 -0.325 _QIEELK(gl)GQEVSPK_
UCHL1 Ubiquitylation K4 -0.164 -0.657 _MQLK(gl)PMEINPEMLNK_
UCHL1 Ubiquitylation K195 -0.285 -0.704 _MPFPVNHGASSEDTLLK(gl)DAAK_
UCHL1 Ubiquitylation K65 -0.004 -0.789 _K(gl)QIEELKGQEVSPK_
UCHL1 Ubiquitylation K78 -0.595 _QIEELKGQEVSPK(gl)VYFMK_
UCHL1 Ubiquitylation K135 -0.048 _CFEK(gl)NEAIQAAHDAVAQEGQCR_

Background Information for UCHL1:


Pubmed-UCHL1 »
Uniprot-UCHL1 »
Biogrid-UCHL1 »
ProteomicsDB-UCHL1 »

Tumorportal-UCHL1 »
COSMIC-UCHL1 »
GenomeRNAi-UCHL1 »
Genecards-UCHL1


Protein-protein Interactions for UCHL1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in UCHL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_C12_UCH IPR001578 0.35


Protein complexes (CORUM database) featuring UCHL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UCHL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members GO Category GO:0043130 ubiquitin binding Database 1.22
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0004197 cysteine-type endopeptidase activity Database 0.38
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0008242 omega peptidase activity Database 0.28
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0008219 cell death Database 0.08
Category members Pathway Pathway_405 PID_ALPHA_SYNUCLEIN_PATHWAY 0 0.08
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0019233 sensory perception of pain Database 0.05
Category members GO Category GO:0002931 response to ischemia Database 0.04
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members Disease phenotype Young_adult-onset_Parkinsonism Young adult-onset Parkinsonism Database 0
Category members GO Category GO:0006950 response to stress Database 0
Category members GO Category GO:0007412 axon target recognition Database 0
Category members GO Category GO:0007628 adult walking behavior Database 0
Category members GO Category GO:0016874 ligase activity Database 0
Category members GO Category GO:0019896 axon transport of mitochondrion Database 0
Category members GO Category GO:0031694 alpha-2A adrenergic receptor binding Database 0
Category members GO Category GO:0042755 eating behavior Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0043407 negative regulation of MAP kinase activity Database 0
Category members GO Category GO:0048747 muscle fiber development Database 0
Category members GO Category GO:0050905 neuromuscular process Database 0


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