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Query: RUNX3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RUNX3 0 0.708 -0.550 0.450

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RUNX3 Ubiquitylation K244 0.258 _NASAVMK(gl)NQVAR_

Background Information for RUNX3:





Protein-protein Interactions for RUNX3

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in RUNX3

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members AML1_Runt IPR000040 0
Category members p53-like_TF_DNA-bd IPR008967 0
Category members Runt_dom IPR013524 0
Category members RunxI_C_dom IPR013711 0
Category members TF_Runt-rel_RUNX IPR016554 0


Protein complexes (CORUM database) featuring RUNX3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RUNX3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0045786 negative regulation of cell cycle Database 0.93
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members Pathway Pathway_845 PID_SMAD2_3NUCLEAR_PATHWAY 0 0.46
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding Database 0.21
Category members GO Category GO:0050680 negative regulation of epithelial cell proliferation Database 0.19
Category members GO Category GO:0002062 chondrocyte differentiation Database 0.13
Category members GO Category GO:0032609 interferon-gamma production Database 0.13
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0031069 hair follicle morphogenesis Database 0.06
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0048469 cell maturation Database 0
Category members GO Category GO:0048935 peripheral nervous system neuron development Database 0


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