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Query: GMNN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GMNN 0 -1.538 0.620 -1.000

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GMNN Ubiquitylation K50 -0.622 -0.151 _ENELSAGLSK(gl)R_
GMNN Phosphorylation S63 0.028 -0.793 _NDHLTSTTS(ph)SPGVIVPESSENK_

Background Information for GMNN:


Pubmed-GMNN »
Uniprot-GMNN »
Biogrid-GMNN »
ProteomicsDB-GMNN »

Tumorportal-GMNN »
COSMIC-GMNN »
GenomeRNAi-GMNN »
Genecards-GMNN


Protein-protein Interactions for GMNN
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCNA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GMNN Cat. description Hein, Mann, Cell 2015
Category members IP bait C2orf68 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC146 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CKS1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CKS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GMNN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNKD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POTEB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUNDC3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGIF2LY Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF785 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GMNN
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Geminin/Multicilin IPR022786 0.18


Protein complexes (CORUM database) featuring GMNN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2210 BRCA1-IRIS-pre-replication complex Database 0.08


Categories featuring GMNN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_787 REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX 0 1.59
Category members Pathway Pathway_331 REACTOME_M_G1_TRANSITION 0 1.43
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0045786 negative regulation of cell cycle Database 0.93
Category members Pathway Pathway_828 REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX 0 0.82
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0042826 histone deacetylase binding Database 0.16
Category members GO Category GO:0006275 regulation of DNA replication Database 0.14
Category members Pathway Pathway_778 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX 0 0.1
Category members GO Category GO:0008156 negative regulation of DNA replication Database 0.03
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0009887 organ morphogenesis Database 0
Category members GO Category GO:0070491 repressing transcription factor binding Database 0


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