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Query: PDCD4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PDCD4 1 6.113 -0.500 1.310
PDCD4 1 6.113 -0.500 1.310 0.149

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PDCD4 Ubiquitylation K242 1.242 _SFDK(gl)LLK_
PDCD4 Phosphorylation S76 1.091 0.816 _GDS(ph)VSDSGSDALR_
PDCD4 Phosphorylation S457 0.751 0.699 _RFVS(ph)EGDGGR_
PDCD4 Phosphorylation T93 -0.214 0.036 _SGLTVPT(ph)SPK_
PDCD4 Phosphorylation S94 -0.407 -0.022 _SGLTVPTS(ph)PK_
PDCD4 Ubiquitylation K245 -0.529 _LLK(gl)DLPELALDTPR_
PDCD4 Ubiquitylation K309 1.505 _ATVLLSMSKGGK(gl)_

Background Information for PDCD4:


Pubmed-PDCD4 »
Uniprot-PDCD4 »
Biogrid-PDCD4 »
ProteomicsDB-PDCD4 »

Tumorportal-PDCD4 »
COSMIC-PDCD4 »
GenomeRNAi-PDCD4 »
Genecards-PDCD4


Protein-protein Interactions for PDCD4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BTRC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMTD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF4A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGIF2LY Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM51 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PDCD4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Initiation_fac_eIF4g_MI IPR003891 0


Protein complexes (CORUM database) featuring PDCD4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5615 Emerin complex 52 Database 0.99


Categories featuring PDCD4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0045786 negative regulation of cell cycle Database 0.93
Category members GO Category GO:0007569 cell aging Database 0.03
Category members GO Category GO:0043508 negative regulation of JUN kinase activity Database 0


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