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Query: ALOX15B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ALOX15B 0 0.144

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ALOX15B Ubiquitylation K214 0.144 _SLNEMK(gl)R_

Background Information for ALOX15B:


Pubmed-ALOX15B »
Uniprot-ALOX15B »
Biogrid-ALOX15B »
ProteomicsDB-ALOX15B »

Tumorportal-ALOX15B »
COSMIC-ALOX15B »
GenomeRNAi-ALOX15B »
Genecards-ALOX15B


Protein-protein Interactions for ALOX15B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALOX15B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ALOX15B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Lipase_LipOase IPR008976 0.02
Category members PLAT/LH2_dom IPR001024 0
Category members LipOase_mml IPR001885 0
Category members LipOase_C IPR013819 0


Protein complexes (CORUM database) featuring ALOX15B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ALOX15B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0045786 negative regulation of cell cycle Database 0.93
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0030856 regulation of epithelial cell differentiation Database 0.23
Category members Pathway Pathway_158 KEGG_ARACHIDONIC_ACID_METABOLISM 0 0.13
Category members GO Category GO:0005506 iron ion binding Database 0.04
Category members GO Category GO:0010744 positive regulation of macrophage derived foam cell differentiation Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0016165 linoleate 13S-lipoxygenase activity Database 0
Category members GO Category GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Database 0
Category members GO Category GO:0019369 arachidonic acid metabolic process Database 0
Category members GO Category GO:0019372 lipoxygenase pathway Database 0
Category members GO Category GO:0030850 prostate gland development Database 0
Category members GO Category GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway Database 0
Category members GO Category GO:0043651 linoleic acid metabolic process Database 0
Category members GO Category GO:0045618 positive regulation of keratinocyte differentiation Database 0
Category members GO Category GO:0045926 negative regulation of growth Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0050473 arachidonate 15-lipoxygenase activity Database 0
Category members GO Category GO:0051122 hepoxilin biosynthetic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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