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Query: RHOB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RHOB 0 -0.231 0.130 -0.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RHOB Ubiquitylation K135 0.050 -0.281 _MK(gl)QEPVRTDDGR_

Background Information for RHOB:


Pubmed-RHOB »
Uniprot-RHOB »
Biogrid-RHOB »
ProteomicsDB-RHOB »

Tumorportal-RHOB »
COSMIC-RHOB »
GenomeRNAi-RHOB »
Genecards-RHOB


Protein-protein Interactions for RHOB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015


Protein Domains in RHOB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase_Rho IPR003578 0.65
Category members Small_GTPase IPR001806 0.65
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32


Protein complexes (CORUM database) featuring RHOB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RHOB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0032154 cleavage furrow Database 2.01
Category members Pathway Pathway_645 PID_CXCR4_PATHWAY 0 1.42
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_674 REACTOME_SEMAPHORIN_INTERACTIONS 0 0.96
Category members GO Category GO:0045786 negative regulation of cell cycle Database 0.93
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0008333 endosome to lysosome transport Database 0.49
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0045766 positive regulation of angiogenesis Database 0.19
Category members GO Category GO:0019003 GDP binding Database 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0000910 cytokinesis Database 0.15
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members Pathway Pathway_56 REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 0 0.11
Category members Pathway Pathway_557 PID_P75_NTR_PATHWAY 0 0.04
Category members Pathway Pathway_642 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE 0 0.02
Category members GO Category GO:0070301 cellular response to hydrogen peroxide Database 0
Category members Pathway Pathway_1032 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING 0 0
Category members Pathway Pathway_1035 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE 0 0
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members Pathway Pathway_623 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS 0 0
Category members GO Category GO:0001525 angiogenesis Database 0
Category members GO Category GO:0006927 transformed cell apoptotic process Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007266 Rho protein signal transduction Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0


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