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Results for the Category
REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE
(Pathway_1035)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
MYH9 1 -1.530 2.620 0.366 -0.040 -0.375 0.136 -0.183
RAC2 1 -1.520 2.710 0.486 -0.364 -0.568
ARHGEF11 1 -1.250 1.080
RHOG 1 0.080 -0.800 1.988 -0.433 -0.542
RHOA 0 -0.510 1.370 -0.485 0.532 0.279
ROCK1 0 -1.420 2.380 -0.112 -0.732
CDC42 0 -0.170 0.490 -0.597 -1.527 -1.013
CDC42 0 1.240 -0.940 -0.597 -1.527 -1.013
MYL6 0 -1.370 1.040 0.873 0.361 -0.268
MYL9 0 0.620 -0.050 -0.507 0.247 -0.166
MYH14 0 -0.990 1.070 0.436 -0.296 0.144 -0.154
MYL12B 0 -0.507 0.247 -0.166
MYH10 0 0.740 -0.560 0.036 0.397 0.165
MYH10 0 0.740 -0.560 -0.265 -0.438
MYH11 0 0.030 0.200 -0.067 0.778
ROCK2 0 -1.660 2.330
RAC1 0 -0.580 1.580 0.486 -0.364 -0.568
ERBB2 0 -1.310 1.360
RHOB 0 0.130 -0.210
RHOC 0 -0.810 0.570
RHOC 0 -0.810 0.570 -0.485 0.532 0.279
SEMA4D 0 -0.540 0.790
SEMA4D 0 0.260 -0.350
ARHGEF12 0 -0.650 0.190

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ARHGEF11 Phosphorylation S216 1.512 _LSLDS(ph)QEGDSGLDSGTER_
ARHGEF11 Phosphorylation S556 0.780 0.048 _SSSQSTFHIPLS(ph)PVEVKPGNVR_
ARHGEF11 Phosphorylation T668 -1.878 _SLENPT(ph)PPFT(ph)PK_
ARHGEF11 Phosphorylation S1155 -0.647 -0.776 _HQVLLEDPEQEGS(ph)AEEEELGVLPCPSTSLDGENR_
ARHGEF11 Phosphorylation T1292 0.389 0.509 _T(ph)RNSGIWESPELDR_
ARHGEF11 Phosphorylation S1295 0.556 0.668 _TRNS(ph)GIWESPELDR_
ARHGEF11 Phosphorylation S1458 1.017 2.592 _SLGGESS(ph)GGTTPVGSFHTEAAR_
ARHGEF11 Phosphorylation S1480 -0.293 _WTDGSLS(ph)PPAKEPLASDSR_
ARHGEF12 Phosphorylation S190 1.083 _ITS(ph)PVLMGEENNVVHNQK_
ARHGEF12 Phosphorylation S309 -0.158 -0.113 _TDCSSGDASRPSSDNADS(ph)PK_
ARHGEF12 Phosphorylation S341 1.105 0.912 _SETIQDTDTQSLVGS(ph)PSTR_
ARHGEF12 Phosphorylation S635 -0.423 _HLSTPSS(ph)VSPEPQDSAK_
ARHGEF12 Phosphorylation S637 -0.340 -0.384 _HLSTPSSVS(ph)PEPQDSAK_
ARHGEF12 Phosphorylation T736 -0.667 -0.391 _VTEHGT(ph)PKPFR_
ARHGEF12 Phosphorylation T1286 0.415 0.112 _T(ph)ASQGPQTDSVIQNSENIK_
ARHGEF12 Phosphorylation S1288 0.339 0.153 _TAS(ph)QGPQTDSVIQNSENIK_
CDC42 Ubiquitylation K173 -1.839 _DDPSTIEK(gl)LAK_
CDC42 Ubiquitylation K178 -0.801 -0.716 _NK(gl)QKPITPETAEK_
CDC42 Ubiquitylation K180 -1.806 _QK(gl)PITPETAEK(gl)LAR_
CDC42 Ubiquitylation K189 -1.082 _QKPITPETAEK(gl)LAR_
CDC42 Ubiquitylation K198 0.550 1.159 _AVK(gl)YVECSALTQK_
CDC42 Ubiquitylation K208 -0.937 0.038 _YVECSALTQK(gl)GLK_
CDC42 Ubiquitylation K228 -2.488 _NVFDEAILAALEPPEPK(gl)K_
CDC42 Ubiquitylation K229 -1.254 _NVFDEAILAALEPPEPKK(gl)_
ERBB2 Ubiquitylation K200 -2.073 _ACHPCSPMCK(gl)GSR_
ERBB2 Ubiquitylation K369 -0.742 _AVTSANIQEFAGCKK(gl)_
ERBB2 Ubiquitylation K747 -0.505 -0.019 _GIWIPDGENVK(gl)IPVAIK_
ERBB2 Ubiquitylation K854 -0.859 _NVLVK(gl)SPNHVK_
ERBB2 Phosphorylation S1054 -0.476 -0.706 _S(ph)GGGDLTLGLEPSEEEAPR_
MYH10 Phosphorylation S225 -0.296 _DHNIPQES(ph)PKPVK_
MYH10 Ubiquitylation K256 0.402 _QLLQANPILESFGNAKTVK(gl)_
MYH10 Ubiquitylation K899 -1.210 _QEEELQAK(gl)DEELLK_
MYH10 Phosphorylation S1979 -0.233 -0.052 _GGPISFS(ph)SSR_
MYH10 Phosphorylation S1980 -0.231 _GGPISFSS(ph)SR_
MYH10 Phosphorylation S1981 -0.541 -0.089 _GGPISFSSS(ph)R_
MYH10 Phosphorylation S1998 0.372 0.302 _QLHLEGASLELS(ph)DDDTESK_
MYH9 Ubiquitylation K66 0.545 _VK(gl)VNKDDIQK_
MYH9 Ubiquitylation K403 0.390 0.869 _DYVQK(gl)AQTK_
MYH9 Ubiquitylation K682 -0.508 _AGK(gl)LDPHLVLDQLR_
MYH9 Ubiquitylation K760 0.409 0.964 _IGQSK(gl)VFFR_
MYH9 Ubiquitylation K821 -0.339 _NCAAYLK(gl)LR_
MYH9 Ubiquitylation K856 -1.336 _EEELVK(gl)VR_
MYH9 Ubiquitylation K860 -0.570 0.212 _VREK(gl)QLAAENR_
MYH9 Ubiquitylation K1274 0.036 _VRTELADK(gl)VTK_
MYH9 Ubiquitylation K1277 0.081 _TELADKVTK(gl)_
MYH9 Ubiquitylation K1413 0.288 _VAAYDKLEK(gl)TK_
MYH9 Ubiquitylation K1415 0.790 _VAAYDKLEKTK(gl)_
MYH9 Phosphorylation S1943 0.168 0.290 _KGAGDGS(ph)DEEVDGKADGAEAK_
MYL12B Phosphorylation T19 0.111 0.686 _AT(ph)SNVFAMFDQSQIQEFK_
MYL12B Phosphorylation S20 0.129 0.526 _ATS(ph)NVFAM(ox)FDQSQIQEFK_
MYL12B Ubiquitylation K150 -0.522 _EAPIDK(gl)KGNFNYIEFTR_
MYL12B Ubiquitylation K151 -0.241 0.032 _K(gl)GNFNYIEFTR_
MYL6 Ubiquitylation K119 -0.008 0.717 _TGDGK(gl)ILYSQCGDVMR_
MYL6 Ubiquitylation K143 -0.749 -0.696 _ALGQNPTNAEVLK(gl)VLGNPK_
MYL6 Ubiquitylation K149 -0.380 -0.299 _VLGNPK(gl)SDEMNVK_
MYL6 Ubiquitylation K174 -0.167 0.427 _NK(gl)DQGTYEDYVEGLR_
MYL9 Phosphorylation T19 0.111 0.686 _AT(ph)SNVFAMFDQSQIQEFK_
MYL9 Phosphorylation S20 0.129 0.526 _ATS(ph)NVFAM(ox)FDQSQIQEFK_
MYL9 Ubiquitylation K150 -0.522 _EAPIDK(gl)KGNFNYIEFTR_
MYL9 Ubiquitylation K151 -0.241 0.032 _K(gl)GNFNYIEFTR_
RAC1 Ubiquitylation K115 -1.745 -0.215 _AK(gl)WYPEVR_
RAC1 Ubiquitylation K142 0.492 _LDLRDDK(gl)DTIEK_
RAC1 Ubiquitylation K152 0.099 -0.292 _K(gl)LTPITYPQGLAMAK_
RAC1 Ubiquitylation K166 -0.981 -0.655 _LTPITYPQGLAMAK(gl)EIGAVK_
RAC1 Ubiquitylation K172 1.026 0.412 _EIGAVK(gl)YLECSALTQR_
RAC1 Ubiquitylation K185 -0.113 0.578 _GLK(gl)TVFDEAIR_
RAC1 Ubiquitylation K202 -1.379 -1.447 _AVLCPPPVK(gl)KR_
RAC1 Ubiquitylation K203 -1.708 -1.447 _AVLCPPPVKK(gl)_
RAC2 Ubiquitylation K115 -1.745 -0.215 _AK(gl)WYPEVR_
RAC2 Ubiquitylation K142 0.492 _LDLRDDK(gl)DTIEK_
RAC2 Ubiquitylation K152 0.099 -0.292 _K(gl)LTPITYPQGLAMAK_
RAC2 Ubiquitylation K166 -0.981 -0.655 _LTPITYPQGLAMAK(gl)EIGAVK_
RAC2 Ubiquitylation K172 1.026 0.412 _EIGAVK(gl)YLECSALTQR_
RAC2 Ubiquitylation K185 -0.113 0.578 _GLK(gl)TVFDEAIR_
RAC2 Ubiquitylation K202 -1.379 -1.447 _AVLCPPPVK(gl)KR_
RAC2 Ubiquitylation K203 -1.708 -1.447 _AVLCPPPVKK(gl)_
RHOA Ubiquitylation K6 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K7 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K118 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K119 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K135 -0.528 -0.796 _MK(gl)QEPVKPEEGRDMANR_
RHOA Ubiquitylation K162 0.345 0.453 _IGAFGYMECSAK(gl)TK_
RHOB Ubiquitylation K135 0.050 -0.281 _MK(gl)QEPVRTDDGR_
RHOC Ubiquitylation K6 0.708 _K(gl)KLVIVGDGACGK_
RHOC Ubiquitylation K7 0.708 _K(gl)KLVIVGDGACGK_
RHOC Ubiquitylation K118 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOC Ubiquitylation K119 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOC Ubiquitylation K135 -0.528 -0.796 _MK(gl)QEPVKPEEGRDMANR_
RHOC Ubiquitylation K162 0.345 0.453 _IGAFGYMECSAK(gl)TK_
RHOC Ubiquitylation K172 0.050 -0.660 _MK(gl)QEPVRSEEGR_
RHOG Ubiquitylation K183 -0.963 _AVLNPTPIK(gl)R_
ROCK1 Phosphorylation S1105 -0.245 -0.845 _LLDLSDSTSVAS(ph)FPSADETDGNLPESR_
ROCK2 Ubiquitylation K1222 -0.679 _ADAK(gl)EIPR_
SEMA4D Ubiquitylation K784 0.913 1.205 _SALLIGKK(gl)_
SEMA4D Ubiquitylation K857 0.832 _DKPFDVK(gl)CELK_


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