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Query: MYH14

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MYH14 0 1.200 -0.990 1.070 0.436 -0.296 0.144 -0.154

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for MYH14:


Pubmed-MYH14 »
Uniprot-MYH14 »
Biogrid-MYH14 »
ProteomicsDB-MYH14 »

Tumorportal-MYH14 »
COSMIC-MYH14 »
GenomeRNAi-MYH14 »
Genecards-MYH14


Protein-protein Interactions for MYH14
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MYH14 Cat. description Hein, Mann, Cell 2015
Category members IP bait FCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UNC45A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MYH14
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Myosin_head_motor_dom IPR001609 0.17
Category members Tropomyosin IPR000533 0.08
Category members IQ_motif_EF-hand-BS IPR000048 0
Category members Myosin_tail IPR002928 0
Category members Myosin_N IPR004009 0
Category members Myosin_S1_N IPR008989 0
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring MYH14
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MYH14
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0030426 growth cone Database 1.61
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members Pathway Pathway_674 REACTOME_SEMAPHORIN_INTERACTIONS 0 0.96
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0016459 myosin complex Database 0.38
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0030898 actin-dependent ATPase activity Database 0.31
Category members GO Category GO:0030048 actin filament-based movement Database 0.28
Category members GO Category GO:0000146 microfilament motor activity Database 0.27
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0003774 motor activity Database 0.2
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0001725 stress fiber Database 0.04
Category members Pathway Pathway_1014 KEGG_VIRAL_MYOCARDITIS 0 0
Category members Pathway Pathway_1032 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING 0 0
Category members Pathway Pathway_1035 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE 0 0
Category members Disease phenotype Autosomal_dominant_nonsyndromic_sensorineural_deafness_type_DFNA Autosomal dominant nonsyndromic sensorineural deafness type DFNA Database 0
Category members GO Category GO:0008360 regulation of cell shape Database 0


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