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Query: TP53BP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TP53BP2 1 2.561 1.060 -0.800 -0.399 -0.481

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TP53BP2 Phosphorylation S569 1.774 _VLLS(ph)PSIPSVGQDQTLS(ph)PGSK_
TP53BP2 Phosphorylation S556 1.443 1.433 _VLLS(ph)PSIPSVGQDQTLSPGSK_
TP53BP2 Phosphorylation S480 0.458 0.944 _NQS(ph)SEDILR_
TP53BP2 Phosphorylation S698 -0.309 -0.362 _IPRPLS(ph)PTK_
TP53BP2 Phosphorylation T700 -0.449 -0.429 _IPRPLSPT(ph)K_
TP53BP2 Phosphorylation S737 -0.172 -0.748 _RSS(ph)ITEPEGPNGPNIQK_
TP53BP2 Ubiquitylation K102 0.149 _SQDPSLK(gl)R_
TP53BP2 Ubiquitylation K152 0.224 _QQQQIEAQQQLLATK(gl)EQR_
TP53BP2 Ubiquitylation K224 -0.390 _LVEEIEQMNNLFQQK(gl)QR_
TP53BP2 Ubiquitylation K234 -0.113 _ELVLAVSK(gl)VEELTR_
TP53BP2 Ubiquitylation K268 -0.429 _LYK(gl)ELQLR_
TP53BP2 Ubiquitylation K283 -0.866 _NKLNQEQNAK(gl)LQQQR_
TP53BP2 Ubiquitylation K303 -0.302 _NSEVAVMDK(gl)R_
TP53BP2 Ubiquitylation K322 -2.045 _AALQQK(gl)ENLPVSSDGNLPQQAASAPSR_

Background Information for TP53BP2:


Pubmed-TP53BP2 »
Uniprot-TP53BP2 »
Biogrid-TP53BP2 »
ProteomicsDB-TP53BP2 »

Tumorportal-TP53BP2 »
COSMIC-TP53BP2 »
GenomeRNAi-TP53BP2 »
Genecards-TP53BP2


Protein-protein Interactions for TP53BP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PARD6A Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6B Cat. description Hein, Mann, Cell 2015
Category members IP bait RASSF8 Cat. description Hein, Mann, Cell 2015
Category members IP bait YAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAH Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAZ Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC101 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FRMD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOMER1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASSF7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASSF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRGAP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TP53BP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0
Category members Ankyrin_rpt IPR002110 0
Category members Spectrin_alpha_SH3 IPR013315 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring TP53BP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TP53BP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0010212 response to ionizing radiation Database 1.66
Category members GO Category GO:0045786 negative regulation of cell cycle Database 0.93
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0051059 NF-kappaB binding Database 0.25
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members GO Category GO:0005070 SH3/SH2 adaptor activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007417 central nervous system development Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0009792 embryo development ending in birth or egg hatching Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0


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