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Query: CREB3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CREB3 0 -0.114 0.180 -0.820

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CREB3 Ubiquitylation K176 -0.114 _TEEQILK(gl)R_

Background Information for CREB3:


Pubmed-CREB3 »
Uniprot-CREB3 »
Biogrid-CREB3 »
ProteomicsDB-CREB3 »

Tumorportal-CREB3 »
COSMIC-CREB3 »
GenomeRNAi-CREB3 »
Genecards-CREB3


Protein-protein Interactions for CREB3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CREB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CREB3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members bZIP IPR004827 0
Category members TF_DNA-bd IPR008917 0


Protein complexes (CORUM database) featuring CREB3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CREB3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0045786 negative regulation of cell cycle Database 0.93
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0006986 response to unfolded protein Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members Pathway Pathway_983 ST_P38_MAPK_PATHWAY 0 0.34
Category members GO Category GO:0008140 cAMP response element binding protein binding Database 0.3
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding Database 0.21
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members Pathway Pathway_165 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES 0 0.18
Category members GO Category GO:0042994 cytoplasmic sequestering of transcription factor Database 0.14
Category members Pathway Pathway_177 KEGG_PROSTATE_CANCER 0 0.13
Category members Pathway Pathway_733 ST_G_ALPHA_S_PATHWAY 0 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0006935 chemotaxis Database 0.09
Category members GO Category GO:0050930 induction of positive chemotaxis Database 0.08
Category members GO Category GO:0034976 response to endoplasmic reticulum stress Database 0.06
Category members Pathway Pathway_1005 ST_ERK1_ERK2_MAPK_PATHWAY 0 0.06
Category members GO Category GO:0042127 regulation of cell proliferation Database 0.06
Category members GO Category GO:0016604 nuclear body Database 0.04
Category members GO Category GO:0031726 CCR1 chemokine receptor binding Database 0.04
Category members Pathway Pathway_517 ST_GRANULE_CELL_SURVIVAL_PATHWAY 0 0.02
Category members Pathway Pathway_244 KEGG_MELANOGENESIS 0 0
Category members Pathway Pathway_266 KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION 0 0
Category members Pathway Pathway_445 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0001558 regulation of cell growth Database 0
Category members GO Category GO:0002230 positive regulation of defense response to virus by host Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response Database 0
Category members GO Category GO:0019043 establishment of viral latency Database 0
Category members GO Category GO:0019046 release from viral latency Database 0
Category members GO Category GO:0030176 integral to endoplasmic reticulum membrane Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0046983 protein dimerization activity Database 0
Category members GO Category GO:0051928 positive regulation of calcium ion transport Database 0


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