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ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS
(Pathway_445)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
JUN 3 -0.930 0.930 -0.126
MAP1B 2 -0.670 1.350 -0.185 -0.818 -0.822 0.106 -0.011
MAPK9 1 0.110 -0.490
TERF2IP 1 0.500 -0.780 -0.491 1.304 2.217 -1.505 -0.760
TERF2IP 1 1.450 -1.010 -0.491 1.304 2.217 -1.505 -0.760
TERF2IP 1 1.580 -0.650 -0.491 1.304 2.217 -1.505 -0.760
RPS6KA3 1 -1.550 2.890
CREBBP 0 0.840 -0.950 -3.889 -1.071
MAPK8IP2 0 1.730 -1.220
MAP2K4 0 -0.300 0.320
MAP2K7 0 0.180 -0.660 -2.110
CRKL 0 0.290 -0.620
MAPK3 0
ASAH1 0 -0.300 0.340
CREB3 0 0.180 -0.820
CREB1 0 1.080 -0.800 -1.027
PIK3CA 0
ATF1 0 0.500 0.320 -0.601 0.001
ELK1 0
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
PIK3R1 0 1.910 -1.220 -0.441 0.147
GNAQ 0 0.140 -0.310 0.052 0.449
BRAF 0
TUBA1A 0 0.200 -0.030 0.742 -0.126 0.853 0.585
DAG1 0 0.210 -0.400
PTPN11 0 -0.210 -0.400 0.644 1.053 0.451
SRC 0 0.050 0.470 -0.031

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
ASAH1 Ubiquitylation K461 0.139 _ESLDVYELDAK(gl)QGR_
ATF1 Phosphorylation S464 0.128 _TTPSATSLPQTVVMTS(ph)PVTLTSQTTK_
ATF1 Ubiquitylation K481 -0.754 _TDDPQLK(gl)R_
ATF1 Ubiquitylation K505 0.609 0.811 _EYVK(gl)CLENR_
BRAF Phosphorylation S151 -0.685 -0.629 _SNPKS(ph)PQKPIVR_
BRAF Phosphorylation S363 -0.023 -0.241 _S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF Phosphorylation S365 -0.286 0.012 _SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF Phosphorylation S399 -0.890 -0.527 _GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF Phosphorylation T401 -0.525 _GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF Phosphorylation S446 0.246 0.349 _RDS(ph)SDDWEIPDGQITVGQR_
BRAF Phosphorylation S447 0.579 0.623 _RDSS(ph)DDWEIPDGQITVGQR_
BRAF Phosphorylation S729 0.208 0.219 _SAS(ph)EPSLNR_
CREB1 Phosphorylation S271 -0.979 -1.450 _TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1 Ubiquitylation K333 1.343 _ALK(gl)DLYCHK_
CREB3 Ubiquitylation K176 -0.114 _TEEQILK(gl)R_
CREBBP Phosphorylation S2093 0.037 0.097 _SIS(ph)PSALQDLLR_
CRKL Phosphorylation S41 0.868 _DS(ph)STCPGDYVLSVSENSR_
CRKL Phosphorylation S107 -0.818 -1.177 _YPS(ph)PPMGSVSAPNLPTAEDNLEYVR_
DAG1 Ubiquitylation K793 0.843 _LTLEDQATFIK(gl)K_
DAG1 Ubiquitylation K794 0.899 _LTLEDQATFIKK(gl)_
DAG1 Ubiquitylation K881 -0.342 _GSRPK(gl)NMTPYR_
ELK1 Phosphorylation S273 -0.601 -0.553 _PAVVLPSAAPAGAAAPPS(ph)GSR_
ELK1 Phosphorylation S275 -0.601 -0.553 _PAVVLPSAAPAGAAAPPS(ph)GSR_
ELK1 Phosphorylation S403 0.568 -0.579 _DLELPLS(ph)PSLLGGPGPER_
GNAQ Ubiquitylation K16 0.245 _TLESIMACCLSEEAK(gl)EAR_
GNAQ Ubiquitylation K102 -0.299 _IPYK(gl)YEHNK_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
MAP1B Phosphorylation S25 -0.855 _(ac)ATVVVEATEPEPSGSIANPAASTS(ph)PSLSHR_
MAP1B Phosphorylation T527 -0.678 _DLTGQVPT(ph)PVVK_
MAP1B Ubiquitylation K531 -1.026 -0.599 _DLTGQVPTPVVK(gl)QTK_
MAP1B Ubiquitylation K534 -0.903 -0.599 _DLTGQVPTPVVK(gl)QTK_
MAP1B Phosphorylation S541 0.527 0.394 _ADS(ph)RESLKPAAK_
MAP1B Phosphorylation S544 0.486 0.444 _ADSRES(ph)LKPAAK_
MAP1B Ubiquitylation K546 -0.416 _ESLK(gl)PAAKPLPSK_
MAP1B Phosphorylation S561 0.422 0.185 _KES(ph)KEETPEVTK_
MAP1B Phosphorylation S614 -0.475 -0.368 _EEPS(ph)PVKAEVAEK_
MAP1B Phosphorylation T704 -0.261 -0.007 _KET(ph)PPKEVK_
MAP1B Phosphorylation T744 0.004 _KSST(ph)PLSEAK_
MAP1B Phosphorylation S831 0.532 _SLMS(ph)SPEDLTKDFEELKAEEVDVTK_
MAP1B Phosphorylation S832 0.365 0.496 _SLMSS(ph)PEDLTK_
MAP1B Phosphorylation S891 -1.994 _GPAES(ph)PDEGITTTEGEGECEQTPEELEPVEK_
MAP1B Phosphorylation S937 1.120 0.235 _FEDEGAGFEESS(ph)ETGDYEEK_
MAP1B Phosphorylation S995 -1.075 0.367 _RESVAS(ph)GDDRAEEDMDEAIEK_
MAP1B Phosphorylation S1016 -0.502 0.343 _GEAEQS(ph)EEEADEEDKAEDAREEEYEPEK_
MAP1B Phosphorylation T1066 0.068 _AAEAGGAEEQYGFLT(ph)TPTK_
MAP1B Phosphorylation T1067 -0.335 0.042 _AAEAGGAEEQYGFLTT(ph)PTK_
MAP1B Phosphorylation S1154 1.021 1.174 _DVMSDETNNEETES(ph)PSQEFVNITK_
MAP1B Phosphorylation S1156 0.647 _DVMSDETNNEETESPS(ph)QEFVNITK_
MAP1B Phosphorylation S1208 0.572 _DYNASASTIS(ph)PPSSMEEDKFSR_
MAP1B Phosphorylation S1252 0.398 0.533 _DSISAVSSEKVS(ph)PSK_
MAP1B Phosphorylation S1256 -1.138 -1.307 _VSPSKS(ph)PSLSPS(ph)PPSPLEK_
MAP1B Phosphorylation S1258 -0.591 _SPS(ph)LSPSPPS(ph)PLEK_
MAP1B Phosphorylation S1260 -0.711 -0.709 _SPSLS(ph)PSPPS(ph)PLEK_
MAP1B Phosphorylation S1262 -0.763 -1.052 _VSPSKS(ph)PSLSPS(ph)PPSPLEK_
MAP1B Phosphorylation S1265 -0.910 -1.117 _SPSLSPSPPS(ph)PLEK_
MAP1B Phosphorylation S1276 -0.527 _S(ph)VNFSLT(ph)PNEIK_
MAP1B Phosphorylation S1280 -0.308 0.146 _SVNFS(ph)LTPNEIK_
MAP1B Phosphorylation T1282 -0.626 0.066 _SVNFSLT(ph)PNEIK_
MAP1B Phosphorylation S1298 -0.381 -0.707 _VSAEAEVAPVS(ph)PEVT(ph)QEVVEEHCASPEDK_
MAP1B Phosphorylation T1302 -0.749 -0.678 _VSAEAEVAPVS(ph)PEVT(ph)QEVVEEHCASPEDK_
MAP1B Phosphorylation S1312 -0.602 -0.379 _VSAEAEVAPVSPEVTQEVVEEHCAS(ph)PEDK_
MAP1B Phosphorylation S1322 0.129 0.348 _TLEVVS(ph)PSQSVTGSAGHTPYYQSPTDEK_
MAP1B Phosphorylation S1330 -0.665 -0.700 _TLEVVS(ph)PSQSVTGS(ph)AGHTPY(ph)YQSPTDEK_
MAP1B Phosphorylation T1334 0.464 0.430 _TLEVVS(ph)PSQSVTGSAGHT(ph)PYYQSPTDEK_
MAP1B Phosphorylation S1339 0.126 0.484 _TLEVVSPSQSVTGSAGHTPYYQS(ph)PTDEK_
MAP1B Phosphorylation S1376 -0.716 0.718 _AS(ph)VSPM(ox)DEPVPDSES(ph)PIEK_
MAP1B Phosphorylation S1378 -0.600 -0.569 _ASVS(ph)PMDEPVPDSES(ph)PIEK_
MAP1B Phosphorylation S1387 0.483 -0.428 _ASVS(ph)PMDEPVPDS(ph)ESPIEK_
MAP1B Phosphorylation S1389 -0.258 -0.272 _ASVSPM(ox)DEPVPDSES(ph)PIEK_
MAP1B Phosphorylation S1396 -0.905 0.337 _VLS(ph)PLRS(ph)PPLIGSESAYESFLSADDK_
MAP1B Phosphorylation S1400 -0.886 -1.191 _S(ph)PPLIGSESAYESFLSADDK_
MAP1B Phosphorylation S1406 0.792 _VLS(ph)PLRSPPLIGS(ph)ESAYESFLSADDK_
MAP1B Phosphorylation S1427 0.018 0.289 _GAES(ph)PFEEK_
MAP1B Phosphorylation S1438 -0.299 0.122 _QGS(ph)PDQVS(ph)PVSEMTSTSLYQDK_
MAP1B Phosphorylation S1443 1.266 1.327 _QGSPDQVS(ph)PVSEMTSTSLYQDK_
MAP1B Phosphorylation S1485 1.627 _KTDDVEAMS(ph)SQPALALDER_
MAP1B Phosphorylation S1486 2.111 _KTDDVEAMSS(ph)QPALALDER_
MAP1B Phosphorylation S1501 0.838 1.021 _LGDVS(ph)PTQIDVSQFGSFK_
MAP1B Phosphorylation T1503 0.995 1.027 _KLGDVSPT(ph)QIDVSQFGSFK_
MAP1B Phosphorylation S1625 -0.799 _PMSISPPDFS(ph)PK_
MAP1B Phosphorylation S1653 0.260 0.031 _SEQSSM(ox)SIEFGQES(ph)PEQSLAMDFSR_
MAP1B Phosphorylation S1779 0.688 0.674 _VQSLEGEKLS(ph)PK_
MAP1B Phosphorylation S1785 0.897 1.004 _SDIS(ph)PLTPR_
MAP1B Phosphorylation T1788 0.677 0.540 _SDISPLT(ph)PR_
MAP1B Phosphorylation S1792 -0.187 -0.207 _ES(ph)SPLYSPTFSDSTSAVK_
MAP1B Phosphorylation S1793 -0.074 -0.296 _ESS(ph)PLYSPTFSDSTSAVK_
MAP1B Phosphorylation S1797 1.055 0.823 _ESSPLYS(ph)PTFSDSTSAVK_
MAP1B Phosphorylation T1799 0.695 1.469 _ESSPLYSPT(ph)FSDSTSAVK_
MAP1B Ubiquitylation K1808 -1.495 -0.115 _ESSPLYSPTFSDSTSAVK(gl)EK_
MAP1B Ubiquitylation K1810 -1.865 -0.115 _EK(gl)TATCHSSSSPPIDAASAEPYGFR_
MAP1B Phosphorylation S1817 -0.296 _TATCHSS(ph)SSPPIDAASAEPYGFR_
MAP1B Phosphorylation S1818 -0.266 -0.171 _TATCHSSS(ph)SPPIDAASAEPYGFR_
MAP1B Phosphorylation S1819 -0.686 0.074 _TATCHSSSS(ph)PPIDAASAEPYGFR_
MAP1B Phosphorylation S1852 1.386 0.904 _DLS(ph)TPGLEK_
MAP1B Phosphorylation T1853 -1.963 _DLST(ph)PGLEK_
MAP1B Ubiquitylation K1858 -1.460 1.384 _DLSTPGLEK(gl)DSGGK_
MAP1B Ubiquitylation K1874 1.187 _TPGDFSYAYQK(gl)PEETTR_
MAP1B Phosphorylation S1881 0.811 1.010 _S(ph)PDEEDYDYESYEK_
MAP1B Ubiquitylation K1894 -1.775 _SPDEEDYDYESYEK(gl)TTR_
MAP1B Ubiquitylation K1908 -0.132 2.253 _TSDVGGYYYEK(gl)IER_
MAP1B Ubiquitylation K1914 -0.610 2.234 _TTK(gl)SPSDSGYSYETIGK_
MAP1B Phosphorylation S1915 0.448 0.648 _TTKS(ph)PSDSGYSYETIGK_
MAP1B Phosphorylation S1917 0.243 _SPS(ph)DSGYSYETIGK_
MAP1B Phosphorylation S1919 0.538 _TTKSPSDS(ph)GYSYETIGK_
MAP1B Ubiquitylation K1928 -0.792 1.758 _SPSDSGYSYETIGK(gl)TTK_
MAP1B Ubiquitylation K1931 -0.736 1.218 _TTK(gl)TPEDGDYSYEIIEK_
MAP1B Phosphorylation T1932 1.222 1.613 _TTKT(ph)PEDGDYSYEIIEK_
MAP1B Ubiquitylation K1945 -1.743 _TPEDGDYSYEIIEK(gl)TTR_
MAP1B Phosphorylation T1949 0.284 0.558 _T(ph)PEEGGYSYDISEK_
MAP1B Phosphorylation S1965 -0.363 -0.143 _TTS(ph)PPEVSGYSYEK_
MAP1B Ubiquitylation K1976 -0.758 1.167 _TTSPPEVSGYSYEK(gl)TER_
MAP1B Ubiquitylation K2030 -0.812 1.692 _ITSFPESEGYSYETSTK(gl)TTR_
MAP1B Phosphorylation T2034 0.068 0.248 _T(ph)PDTSTYCYETAEK_
MAP1B Phosphorylation S2098 -2.109 _TELS(ph)PSFINPNPLEWFASEEPTEESEKPLTQSGGAPPPPGGK_
MAP1B Phosphorylation S2271 -1.264 -0.904 _SKPLAAS(ph)PKPAGLK_
MAP1B Phosphorylation T2305 -1.243 -0.115 _AAKPTTT(ph)PEVK_
MAP2K4 Phosphorylation S80 0.441 _LRTHS(ph)IESSGK_
MAP2K7 Ubiquitylation K9 -1.406 _(ac)AASSLEQK(gl)LSR_
MAP2K7 Ubiquitylation K300 -1.228 _GQIK(gl)LCDFGISGR_
MAP2K7 Ubiquitylation K442 -1.326 _DVMAK(gl)TESPR_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
MAPK8IP2 Ubiquitylation K674 -0.899 0.671 _DLLGSK(gl)R_
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_
PIK3CA Ubiquitylation K864 0.390 0.588 _NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA Ubiquitylation K868 0.204 0.651 _NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA Ubiquitylation K974 -0.273 _GAQECTK(gl)TREFER_
PTPN11 Ubiquitylation K124 0.562 _EAEK(gl)LLTEK_
RPS6KA3 Phosphorylation S227 0.363 0.496 _AYS(ph)FCGTVEYM(ox)APEVVNR_
RPS6KA3 Phosphorylation T231 0.315 _KAYSFCGT(ph)VEYMAPEVVNR_
RPS6KA3 Ubiquitylation K322 -0.076 -0.376 _LGAGPDGVEEIK(gl)R_
RPS6KA3 Phosphorylation T365 -0.892 -1.003 _T(ph)PKDSPGIPPSANAHQLFR_
RPS6KA3 Phosphorylation S369 -0.621 -0.862 _TPKDS(ph)PGIPPSANAHQLFR_
RPS6KA3 Ubiquitylation K566 -0.152 _ICDFGFAK(gl)QLR_
RPS6KA3 Phosphorylation S715 -0.923 -0.880 _NQS(ph)PVLEPVGR_
SRC Phosphorylation S17 -0.604 -0.689 _S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC Phosphorylation S75 0.060 0.331 _LFGGFNSSDTVTS(ph)PQR_
TERF2IP Phosphorylation S36 0.199 -0.039 _DDGSSMSFYVRPS(ph)PAK_
TERF2IP Phosphorylation S154 0.255 -0.049 _S(ph)PSSVTGNALWK_
TERF2IP Phosphorylation S156 0.369 0.179 _ENARSPS(ph)SVTGNALWK_
TERF2IP Phosphorylation S157 0.410 _ENARSPSS(ph)VTGNALWK_
TERF2IP Phosphorylation S203 -0.351 -0.260 _YLLGDAPVS(ph)PSSQK_
TERF2IP Ubiquitylation K228 -0.229 _KAEEDPEAADSGEPQNK(gl)R_


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