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Query: TUBA1A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TUBA1A 0 2.054 0.200 -0.030 0.742 -0.126 0.853 0.585

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for TUBA1A:


Pubmed-TUBA1A »
Uniprot-TUBA1A »
Biogrid-TUBA1A »
ProteomicsDB-TUBA1A »

Tumorportal-TUBA1A »
COSMIC-TUBA1A »
GenomeRNAi-TUBA1A »
Genecards-TUBA1A


Protein-protein Interactions for TUBA1A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC37 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2C Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF5B Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait ADAMTS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ANTXR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD79B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTDSP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNAJB11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait F9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM187B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM196A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM5C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INSL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1967 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLK11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXPH3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RCCD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THBS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TKTL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPSB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBA1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBA1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBA3C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXNDC9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF695 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TUBA1A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tubulin IPR000217 0
Category members Alpha_tubulin IPR002452 0
Category members Beta_tubulin IPR002453 0
Category members Delta_tubulin IPR002967 0
Category members Tubulin_FtsZ_GTPase IPR003008 0
Category members Epsilon_tubulin IPR004057 0
Category members Tub_FtsZ_C IPR008280 0
Category members Tubulin/FtsZ_2-layer-sand-dom IPR018316 0


Protein complexes (CORUM database) featuring TUBA1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF
Category members Corum 1231 FIB-associated protein complex Database 0


Categories featuring TUBA1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0006457 protein folding Database 4.93
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0051084 'de novo' posttranslational protein folding Database 0.63
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_1026 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 0 0.45
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members Pathway Pathway_1288 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC 0 0.4
Category members Pathway Pathway_54 BIOCARTA_MTA3_PATHWAY 0 0.36
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0007017 microtubule-based process Database 0.3
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0071353 cellular response to interleukin-4 Database 0.19
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0030705 cytoskeleton-dependent intracellular transport Database 0.13
Category members Pathway Pathway_200 PID_P73PATHWAY 0 0.11
Category members Pathway Pathway_213 KEGG_GAP_JUNCTION 0 0.11
Category members Pathway Pathway_1296 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC 0 0.08
Category members Pathway Pathway_1295 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY 0 0.07
Category members GO Category GO:0005881 cytoplasmic microtubule Database 0.04
Category members Disease phenotype Intellectual_disability Intellectual disability Database 0.04
Category members Pathway Pathway_445 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS 0 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0051258 protein polymerization Database 0


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