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Query: ETS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ETS1 1 7.479 1.070 -0.650

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ETS1 Ubiquitylation K416 7.479 _MNYEK(gl)LSR_
ETS1 Ubiquitylation K427 -0.895 _YYYDK(gl)NIIHK_

Background Information for ETS1:





Protein-protein Interactions for ETS1

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in ETS1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ets_dom IPR000418 0.07
Category members Pointed_dom IPR003118 0
Category members SAM/pointed IPR013761 0
Category members Transform_prot_C-ets IPR016311 0


Protein complexes (CORUM database) featuring ETS1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2790 ETS2-ETS1 complex Database 0


Categories featuring ETS1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members Pathway Pathway_541 PID_FAK_PATHWAY 0 1.88
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006955 immune response Database 1.22
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0045786 negative regulation of cell cycle Database 0.93
Category members Pathway Pathway_507 PID_MET_PATHWAY 0 0.82
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0051272 positive regulation of cellular component movement Database 0.46
Category members GO Category GO:0030578 PML body organization Database 0.39
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0045765 regulation of angiogenesis Database 0.24
Category members GO Category GO:0009612 response to mechanical stimulus Database 0.23
Category members GO Category GO:0045648 positive regulation of erythrocyte differentiation Database 0.23
Category members GO Category GO:0060206 estrous cycle phase Database 0.23
Category members Pathway Pathway_762 PID_HIF2PATHWAY 0 0.23
Category members Pathway Pathway_210 PID_CMYB_PATHWAY 0 0.2
Category members GO Category GO:0045766 positive regulation of angiogenesis Database 0.19
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0007565 female pregnancy Database 0.19
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Pathway Pathway_52 PID_HIF1_TFPATHWAY 0 0.11
Category members GO Category GO:0046677 response to antibiotic Database 0.08
Category members Pathway Pathway_434 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY 0 0.04
Category members Pathway Pathway_23 KEGG_RENAL_CELL_CARCINOMA 0 0.03
Category members GO Category GO:0070555 response to interleukin-1 Database 0.02
Category members GO Category GO:0070301 cellular response to hydrogen peroxide Database 0
Category members Pathway Pathway_1048 BIOCARTA_KERATINOCYTE_PATHWAY 0 0
Category members Pathway Pathway_1073 KEGG_DORSO_VENTRAL_AXIS_FORMATION 0 0
Category members Pathway Pathway_1097 BIOCARTA_ETS_PATHWAY 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_419 PID_IL4_2PATHWAY 0 0
Category members Pathway Pathway_443 PID_AP1_PATHWAY 0 0
Category members Pathway Pathway_540 PID_BCR_5PATHWAY 0 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0009611 response to wounding Database 0
Category members GO Category GO:0010595 positive regulation of endothelial cell migration Database 0
Category members GO Category GO:0010715 regulation of extracellular matrix disassembly Database 0
Category members GO Category GO:0021854 hypothalamus development Database 0
Category members GO Category GO:0021983 pituitary gland development Database 0
Category members GO Category GO:0030262 apoptotic nuclear changes Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0032355 response to estradiol Database 0
Category members GO Category GO:0034616 response to laminar fluid shear stress Database 0
Category members GO Category GO:0035035 histone acetyltransferase binding Database 0
Category members GO Category GO:0048870 cell motility Database 0
Category members GO Category GO:0060055 angiogenesis involved in wound healing Database 0


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