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negative regulation of Notch signaling pathway
(GO:0045746)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
NRARP 1 0.370 -0.770
BMP7 0
DLX2 0 -0.930 1.950 -1.286 0.204
CHAC1 0 -0.520 0.590
NUMB 0 0.310 0.050
DLX1 0 -1.110 0.780
DLX1 0 -1.110 0.780 -1.286 0.204
GDPD5 0 1.980 -0.470
HIF1AN 0 0.620 -0.310
EGFL7 0 -1.200 1.990

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BMP7 Ubiquitylation K178 -0.107 _IYK(gl)DYIR_
CHAC1 Ubiquitylation K151 0.442 -0.540 _ALK(gl)YLNVR_
DLX1 Phosphorylation S9 0.286 0.248 _(ac)M(ox)TM(ox)TTM(ox)PES(ph)LNSPVSGK_
DLX1 Phosphorylation S225 -0.821 _SGEIPSEQHPGAS(ph)AS(ph)PPCASPPVSAPASWDFGVPQR_
DLX1 Phosphorylation S227 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
DLX1 Phosphorylation S232 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
DLX2 Phosphorylation S225 -0.821 _SGEIPSEQHPGAS(ph)AS(ph)PPCASPPVSAPASWDFGVPQR_
DLX2 Phosphorylation S227 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
DLX2 Phosphorylation S232 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
EGFL7 Ubiquitylation K93 -1.651 _YACCPGWK(gl)R_
GDPD5 Ubiquitylation K597 0.343 _GGGSHTK(gl)TLIER_
HIF1AN Ubiquitylation K106 0.161 _FLYYDEK(gl)K_
HIF1AN Ubiquitylation K115 -0.227 -0.105 _MANFQNFK(gl)PR_
NRARP Phosphorylation S2 1.670 _(ac)S(ph)QAELSTCSAPQTQR_
NRARP Ubiquitylation K24 -0.011 _IFQEAVRK(gl)_
NUMB Ubiquitylation K63 0.281 _GMHICEDAVK(gl)R_
NUMB Phosphorylation T436 0.878 _RT(ph)PSEADRWLEEVSK_


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