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bioLOGIC Data

Query: DLX1

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
DLX1	0	1.518	-1.110	0.780
DLX1	0	1.518	-1.110	0.780		-1.286	0.204

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
DLX1	Phosphorylation	S9	0.286	0.248	_(ac)M(ox)TM(ox)TTM(ox)PES(ph)LNSPVSGK_
DLX1	Phosphorylation	S225		-0.821	_SGEIPSEQHPGAS(ph)AS(ph)PPCASPPVSAPASWDFGVPQR_
DLX1	Phosphorylation	S227		-1.137	_SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
DLX1	Phosphorylation	S232		-1.137	_SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_

Background Information for DLX1:

Pubmed-DLX1 »

Uniprot-DLX1 »

Biogrid-DLX1 »

ProteomicsDB-DLX1 »

Tumorportal-DLX1 »

COSMIC-DLX1 »

GenomeRNAi-DLX1 »

Genecards-DLX1

Protein-protein Interactions for DLX1

Show screen data for	Category Name and Description	Link to cat description	Data Source

Protein Domains in DLX1

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Homeobox_dom	IPR001356	0.63
Category members	HTH_motif	IPR000047	0.39
Category members	Homeobox_metazoa	IPR020479	0.28
Category members	Homeodomain-like	IPR009057	0

Protein complexes (CORUM database) featuring DLX1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring DLX1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0003682	chromatin binding	Database	6.07
Category members	GO Category	GO:0003677	DNA binding	Database	1.53
Category members	GO Category	GO:0043524	negative regulation of neuron apoptotic process	Database	0.66
Category members	GO Category	GO:0003700	sequence-specific DNA binding transcription factor activity	Database	0.63
Category members	Pathway	Pathway_845	PID_SMAD2_3NUCLEAR_PATHWAY	0	0.46
Category members	GO Category	GO:0007275	multicellular organismal development	Database	0.31
Category members	GO Category	GO:0021879	forebrain neuron differentiation	Database	0.19
Category members	GO Category	GO:0043565	sequence-specific DNA binding	Database	0.18
Category members	GO Category	GO:0000976	transcription regulatory region sequence-specific DNA binding	Database	0.13
Category members	GO Category	GO:0030154	cell differentiation	Database	0.06
Category members	GO Category	GO:0009954	proximal/distal pattern formation	Database	0.04
Category members	GO Category	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Database	0.02
Category members	GO Category	GO:0006355	regulation of transcription, DNA-dependent	Database	0
Category members	GO Category	GO:0021544	subpallium development	Database	0
Category members	GO Category	GO:0021766	hippocampus development	Database	0
Category members	GO Category	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	Database	0
Category members	GO Category	GO:0021892	cerebral cortex GABAergic interneuron differentiation	Database	0
Category members	GO Category	GO:0021893	cerebral cortex GABAergic interneuron fate commitment	Database	0
Category members	GO Category	GO:0042475	odontogenesis of dentin-containing tooth	Database	0
Category members	GO Category	GO:0045746	negative regulation of Notch signaling pathway	Database	0
Category members	GO Category	GO:0048706	embryonic skeletal system development	Database	0
Category members	GO Category	GO:0048715	negative regulation of oligodendrocyte differentiation	Database	0