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Query: HIF1AN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HIF1AN 0 -0.066 0.620 -0.310

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HIF1AN Ubiquitylation K106 0.161 _FLYYDEK(gl)K_
HIF1AN Ubiquitylation K115 -0.227 -0.105 _MANFQNFK(gl)PR_

Background Information for HIF1AN:


Pubmed-HIF1AN »
Uniprot-HIF1AN »
Biogrid-HIF1AN »
ProteomicsDB-HIF1AN »

Tumorportal-HIF1AN »
COSMIC-HIF1AN »
GenomeRNAi-HIF1AN »
Genecards-HIF1AN


Protein-protein Interactions for HIF1AN
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANKDD1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ANKRD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ANKRD49 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ANKRD55 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASB10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASB16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASB4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASB6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASB8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASB9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC94 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIF1AN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NFKBIA Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HIF1AN
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members JmjC_dom IPR003347 0


Protein complexes (CORUM database) featuring HIF1AN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HIF1AN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members Pathway Pathway_753 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN 0 0.35
Category members GO Category GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia Database 0.32
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0051059 NF-kappaB binding Database 0.25
Category members Pathway Pathway_762 PID_HIF2PATHWAY 0 0.23
Category members GO Category GO:0005112 Notch binding Database 0.14
Category members GO Category GO:0048037 cofactor binding Database 0.08
Category members GO Category GO:0005506 iron ion binding Database 0.04
Category members Pathway Pathway_976 PID_HIF1A_PATHWAY 0 0
Category members GO Category GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Database 0
Category members GO Category GO:0019826 oxygen sensor activity Database 0
Category members GO Category GO:0031406 carboxylic acid binding Database 0
Category members GO Category GO:0042264 peptidyl-aspartic acid hydroxylation Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0045663 positive regulation of myoblast differentiation Database 0
Category members GO Category GO:0045746 negative regulation of Notch signaling pathway Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0
Category members GO Category GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia Database 0
Category members GO Category GO:0071456 cellular response to hypoxia Database 0


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