bioLOGIC Category
Results for the Category
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
(GO:0016706)
| RNAi screen result
|
RNAPII IP (MG132) |
CSB IP |
CSB IP (MG132) |
Chrom. |
Chrom. (MG132) |
Ubi /Phospo |
Ubi /Phospho (MG132) |
| W |
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| Gene name |
MGoogle Score |
RNAi high |
RNAi low |
RNAPII-IP (MG132) |
CSB-IP |
CSB-IP (MG132) |
Chrom. |
Chrom. (MG132) |
|
P3H1
|
1
|
-2.060
|
3.660
|
|
|
-0.329
|
0.349
|
0.449
|
|
P4HA2
|
0
|
0.360
|
0.270
|
|
|
|
|
|
|
KDM5A
|
0
|
|
|
|
|
|
0.183
|
-0.131
|
|
PLOD1
|
0
|
1.110
|
-1.080
|
0.314
|
0.119
|
0.095
|
0.283
|
0.387
|
|
OGFOD1
|
0
|
1.500
|
-0.660
|
|
|
|
|
|
|
P3H2
|
0
|
-0.270
|
0.450
|
|
|
-0.329
|
0.349
|
0.449
|
|
ALKBH5
|
0
|
|
|
|
|
|
|
|
|
ALKBH5
|
0
|
|
|
|
|
|
-1.740
|
-1.429
|
|
PLOD3
|
0
|
1.080
|
-0.590
|
|
|
|
|
|
|
PLOD3
|
0
|
1.080
|
-0.590
|
|
|
|
0.104
|
0.379
|
|
KDM5B
|
0
|
-0.730
|
0.300
|
|
|
|
-3.462
|
-0.499
|
|
P4HA1
|
0
|
0.470
|
-0.420
|
0.858
|
|
|
0.668
|
-0.158
|
|
EGLN3
|
0
|
-1.310
|
1.790
|
|
|
|
|
|
|
EGLN1
|
0
|
0.180
|
-0.270
|
-1.041
|
|
|
|
|
|
PLOD2
|
0
|
0.210
|
0.170
|
-0.536
|
|
|
0.258
|
0.338
|
|
TYW5
|
0
|
-0.610
|
0.270
|
|
|
|
|
|
|
HIF1AN
|
0
|
0.620
|
-0.310
|
|
|
|
|
|
|
OGFOD3
|
0
|
0.450
|
-0.540
|
|
|
|
|
1.381
|
|
ALKBH2
|
0
|
-0.380
|
0.650
|
|
|
|
|
|
| Gene name |
PTM type |
PTM site |
UV |
UV (MG132) |
Sequence |
|
ALKBH2
|
Ubiquitylation
|
K7
|
|
-1.140
|
_FLVK(gl)GAQGGLLR_
|
|
ALKBH5
|
Phosphorylation
|
S53
|
-0.052
|
0.112
|
_YQEDS(ph)DPERSDYEEQQLQKEEEAR_
|
|
ALKBH5
|
Phosphorylation
|
S58
|
0.406
|
0.783
|
_YQEDSDPERS(ph)DYEEQQLQKEEEAR_
|
|
ALKBH5
|
Phosphorylation
|
S350
|
0.191
|
0.601
|
_RGS(ph)FSSENYWR_
|
|
ALKBH5
|
Phosphorylation
|
S360
|
0.516
|
0.891
|
_S(ph)YESSEDCSEAAGSPAR_
|
|
ALKBH5
|
Phosphorylation
|
S373
|
-0.831
|
-1.705
|
_SYESSEDCSEAAGS(ph)PAR_
|
|
EGLN1
|
Phosphorylation
|
S12
|
-1.100
|
-0.639
|
_(ac)ANDSGGPGGPS(ph)PSER_
|
|
EGLN1
|
Phosphorylation
|
S125
|
-1.027
|
-0.755
|
_AKPPADPAAAAS(ph)PCR_
|
|
EGLN3
|
Ubiquitylation
|
K48
|
|
-0.501
|
_VK(gl)QLHCTGALR_
|
|
EGLN3
|
Ubiquitylation
|
K111
|
|
-0.831
|
_LGK(gl)YYVK_
|
|
HIF1AN
|
Ubiquitylation
|
K106
|
|
0.161
|
_FLYYDEK(gl)K_
|
|
HIF1AN
|
Ubiquitylation
|
K115
|
-0.227
|
-0.105
|
_MANFQNFK(gl)PR_
|
|
KDM5A
|
Ubiquitylation
|
K135
|
|
-0.691
|
_GGFEMVTK(gl)EK_
|
|
KDM5A
|
Ubiquitylation
|
K137
|
|
-0.691
|
_GGFEMVTK(gl)EK_
|
|
KDM5A
|
Ubiquitylation
|
K159
|
|
-0.589
|
_GTGSLLK(gl)SHYER_
|
|
KDM5A
|
Ubiquitylation
|
K805
|
|
-0.328
|
_EAETCASVAQLLLSKK(gl)_
|
|
KDM5A
|
Phosphorylation
|
S1111
|
-0.424
|
0.369
|
_DLDLEPLS(ph)DLEEGLEETR_
|
|
KDM5A
|
Phosphorylation
|
S1666
|
|
-1.341
|
_KQGPVS(ph)PGPAPPPSFIMSYK_
|
|
KDM5B
|
Ubiquitylation
|
K158
|
|
0.884
|
_IATK(gl)MGFAPGK_
|
|
KDM5B
|
Ubiquitylation
|
K242
|
-1.046
|
-0.314
|
_AEAMNIK(gl)IEPEETTEAR_
|
|
KDM5B
|
Ubiquitylation
|
K639
|
|
-0.221
|
_MASK(gl)ADVLDVVVASTVQK_
|
|
KDM5B
|
Ubiquitylation
|
K832
|
|
-0.689
|
_SGGGK(gl)SQNQLTVNELR_
|
|
KDM5B
|
Ubiquitylation
|
K1102
|
|
-0.038
|
_CDIGLLGLK(gl)R_
|
|
KDM5B
|
Ubiquitylation
|
K1136
|
|
-0.421
|
_ALTESK(gl)ETASAMATLGEAR_
|
|
KDM5B
|
Ubiquitylation
|
K1276
|
|
-0.023
|
_AQQLLSSGNLK(gl)FVQDR_
|
|
OGFOD1
|
Ubiquitylation
|
K105
|
|
-0.466
|
_FQQSDDLK(gl)K_
|
|
OGFOD1
|
Ubiquitylation
|
K106
|
1.064
|
|
_FQQSDDLKK(gl)_
|
|
OGFOD1
|
Ubiquitylation
|
K198
|
|
-0.702
|
_QIVK(gl)SLIPSWNK_
|
|
OGFOD1
|
Ubiquitylation
|
K346
|
|
0.214
|
_ECMK(gl)LFR_
|
|
OGFOD1
|
Ubiquitylation
|
K511
|
|
-0.308
|
_ETLK(gl)FVK_
|
|
P4HA2
|
Ubiquitylation
|
K300
|
|
-0.417
|
_GEGVK(gl)LTPR_
|
|
PLOD3
|
Ubiquitylation
|
K215
|
|
1.464
|
_LSLNLDHK(gl)SR_
|
|
TYW5
|
Ubiquitylation
|
K191
|
0.329
|
|
_DAQYLYLK(gl)GTK_
|
© Copyright Svejstrup Laboratory 2015