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Query: ALKBH2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ALKBH2 0 -0.490 -0.380 0.650

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ALKBH2 Ubiquitylation K7 -1.140 _FLVK(gl)GAQGGLLR_

Background Information for ALKBH2:


Pubmed-ALKBH2 »
Uniprot-ALKBH2 »
Biogrid-ALKBH2 »
ProteomicsDB-ALKBH2 »

Tumorportal-ALKBH2 »
COSMIC-ALKBH2 »
GenomeRNAi-ALKBH2 »
Genecards-ALKBH2


Protein-protein Interactions for ALKBH2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FERMT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF19 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SESN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait AARSD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ALKBH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LCN15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ALKBH2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Oxoglu/Fe-dep_dioxygenase IPR005123 0


Protein complexes (CORUM database) featuring ALKBH2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ALKBH2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members Pathway Pathway_338 REACTOME_DNA_REPAIR 0 8.18
Category members GO Category GO:0006307 DNA dealkylation involved in DNA repair Database 0
Category members GO Category GO:0008198 ferrous iron binding Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Database 0
Category members GO Category GO:0043734 DNA-N1-methyladenine dioxygenase activity Database 0
Category members GO Category GO:0051747 cytosine C-5 DNA demethylase activity Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0
Category members GO Category GO:0070989 oxidative demethylation Database 0


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