bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: KDM5B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KDM5B 0 -3.823 -0.730 0.300 -3.462 -0.499

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KDM5B Ubiquitylation K158 0.884 _IATK(gl)MGFAPGK_
KDM5B Ubiquitylation K1276 -0.023 _AQQLLSSGNLK(gl)FVQDR_
KDM5B Ubiquitylation K1102 -0.038 _CDIGLLGLK(gl)R_
KDM5B Ubiquitylation K639 -0.221 _MASK(gl)ADVLDVVVASTVQK_
KDM5B Ubiquitylation K242 -1.046 -0.314 _AEAMNIK(gl)IEPEETTEAR_
KDM5B Ubiquitylation K1136 -0.421 _ALTESK(gl)ETASAMATLGEAR_
KDM5B Ubiquitylation K832 -0.689 _SGGGK(gl)SQNQLTVNELR_

Background Information for KDM5B:


Pubmed-KDM5B »
Uniprot-KDM5B »
Biogrid-KDM5B »
ProteomicsDB-KDM5B »

Tumorportal-KDM5B »
COSMIC-KDM5B »
GenomeRNAi-KDM5B »
Genecards-KDM5B


Protein-protein Interactions for KDM5B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FAM90A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KDM5B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members Znf_C5HC2 IPR004198 0.33
Category members Lys_sp_deMease_like_dom IPR013637 0.18
Category members TF_JmjN IPR003349 0.08
Category members ARID/BRIGHT_DNA-bd IPR001606 0
Category members JmjC_dom IPR003347 0


Protein complexes (CORUM database) featuring KDM5B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KDM5B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0034720 histone H3-K4 demethylation Database 0.05
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Database 0
Category members GO Category GO:0032453 histone demethylase activity (H3-K4 specific) Database 0
Category members GO Category GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific) Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


.

© Copyright Svejstrup Laboratory 2015