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BIOCARTA_ALK_PATHWAY
(Pathway_872)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RFC1 3 2.530 -1.230 0.635 1.060 1.028 0.826
GSK3B 2 1.020 -0.870 -1.128 1.091
ATF2 2 -1.380 1.800
MEF2C 0 -0.980 1.550
MEF2C 0 -0.980 1.550
BMP7 0
TGFB1 0 -0.550 1.050
TGFBR1 0 -0.260 0.020
BMPR1A 0 0.020 -0.130
SMAD5 0 0.640 -0.430
TGFB3 0 0.900 -0.540
MAP3K7 0 -1.120 1.140 -1.048
GATA4 0 -0.670 0.350
SMAD4 0 0.420 -0.390 0.020 0.556 -0.485
CTNNB1 0 0.490 -0.230
CTNNB1 0 0.490 -0.230 -0.415 0.628 0.215
NKX2-5 0 -0.150 1.230 0.174 0.236
NKX2-5 0 -0.150 1.230 -0.123

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATF2 Phosphorylation T71 -1.263 -1.166 _NDSVIVADQTPT(ph)PTR_
ATF2 Phosphorylation S90 2.624 2.389 _NCEEVGLFNELAS(ph)PFENEFKK_
ATF2 Phosphorylation S112 1.025 1.118 _MPLDLS(ph)PLATPIIR_
BMP7 Ubiquitylation K178 -0.107 _IYK(gl)DYIR_
BMPR1A Ubiquitylation K232 -0.391 0.172 _TIAK(gl)QIQMVR_
BMPR1A Ubiquitylation K477 0.265 -0.134 _EVVCVK(gl)R_
CTNNB1 Ubiquitylation K158 -1.265 _AIPELTK(gl)LLNDEDQVVVNK_
CTNNB1 Ubiquitylation K180 -0.546 -0.636 _AAVM(ox)VHQLSK(gl)K_
CTNNB1 Ubiquitylation K181 -0.717 -0.729 _AAVMVHQLSKK(gl)_
CTNNB1 Phosphorylation S191 -0.024 0.129 _S(ph)PQMVSAIVR_
CTNNB1 Ubiquitylation K435 -0.350 _NK(gl)MM(ox)VCQVGGIEALVR_
CTNNB1 Ubiquitylation K496 -1.262 _LHYGLPVVVK(gl)_
CTNNB1 Phosphorylation S552 1.233 1.224 _RTS(ph)MGGTQQQFVEGVR_
CTNNB1 Phosphorylation T556 1.275 0.995 _RTSM(ox)GGT(ph)QQQFVEGVR_
CTNNB1 Ubiquitylation K671 -0.941 -0.934 _MSEDKPQDYK(gl)K_
GATA4 Phosphorylation S109 -0.520 -0.425 _FS(ph)FPGTTGSLAAAAAAAAAR_
GATA4 Phosphorylation S407 -0.185 0.124 _LS(ph)PQGYASPVSQSPQTSSK_
GSK3B Phosphorylation S9 -0.483 0.010 _TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B Ubiquitylation K85 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Ubiquitylation K86 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Phosphorylation S215 0.296 0.477 _GEPNVS(ph)YICSR_
GSK3B Phosphorylation Y216 0.356 0.376 _GEPNVSY(ph)ICSR_
GSK3B Phosphorylation T390 2.800 2.527 _IQAAAST(ph)PTNATAASDANTGDR_
MAP3K7 Phosphorylation S374 0.149 -0.337 _GS(ph)SVESLPPTSEGK_
MAP3K7 Phosphorylation S375 0.171 -0.087 _GSS(ph)VESLPPTSEGK_
MAP3K7 Phosphorylation S389 1.072 1.445 _RMS(ph)ADMSEIEAR_
MAP3K7 Phosphorylation S439 0.246 0.198 _S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7 Ubiquitylation K474 -0.385 -0.242 _MITTSGPTSEK(gl)PTR_
MAP3K7 Ubiquitylation K589 -0.104 _SLSTYYQQCK(gl)K_
MAP3K7 Ubiquitylation K590 -0.551 0.560 _K(gl)QLEVIR_
MEF2C Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2C Phosphorylation S240 0.008 0.302 _NS(ph)PGLLVSPGNLNK_
MEF2C Phosphorylation S406 0.272 0.338 _SEPVS(ph)PPRDR_
RFC1 Phosphorylation S156 -0.050 0.188 _NKPLS(ph)PIK_
RFC1 Phosphorylation T161 2.131 1.586 _NKPLS(ph)PIKLT(ph)PTSVLDYFGTGSVQR_
RFC1 Phosphorylation T163 1.551 _NKPLS(ph)PIKLTPT(ph)SVLDYFGTGSVQR_
RFC1 Phosphorylation S190 2.756 2.241 _ELS(ph)QNTDESGLNDEAIAK_
RFC1 Ubiquitylation K240 0.991 _TLAMLDEEPKTKK(gl)_
RFC1 Ubiquitylation K271 0.551 _VK(gl)TAQVSDERK_
RFC1 Phosphorylation S368 0.431 0.440 _KESVS(ph)PEDSEK_
RFC1 Ubiquitylation K436 -0.227 _YGGK(gl)VTGNVSK_
RFC1 Ubiquitylation K498 0.781 _SKYEIAVETEMK(gl)K_
RFC1 Ubiquitylation K499 0.781 _SKYEIAVETEMK(gl)K_
SMAD5 Ubiquitylation K64 -2.082 -1.647 _ALSSPGQPSK(gl)CVTIPR_
TGFB1 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TGFB3 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TGFBR1 Ubiquitylation K449 -0.991 _VVCEQK(gl)LRPNIPNR_
TGFBR1 Ubiquitylation K502 0.553 0.430 _TLSQLSQQEGIK(gl)M_


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