Results for the Category
positive regulation of pathway-restricted SMAD protein phosphorylation
(GO:0010862)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| BMP7 | 0 | |||||||
| TGFB1 | 0 | -0.550 | 1.050 | |||||
| TGFBR1 | 0 | -0.260 | 0.020 | |||||
| BMPR1A | 0 | 0.020 | -0.130 | |||||
| TTK | 0 | 1.100 | -0.950 | -1.137 | -0.932 | |||
| TGFB3 | 0 | 0.900 | -0.540 | |||||
| ACVR1B | 0 | -0.720 | 1.030 | |||||
| SMAD4 | 0 | 0.420 | -0.390 | 0.020 | 0.556 | -0.485 | ||
| DAB2 | 0 | 0.510 | -0.470 | |||||
| BMP6 | 0 | 1.970 | -0.630 | |||||
| RBPMS | 0 | -0.920 | 1.850 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ACVR1B | Ubiquitylation | K215 | 0.000 | _TIVLQEIIGK(gl)GR_ | |
| BMP6 | Ubiquitylation | K409 | -1.025 | _VSSASDYNSSELK(gl)TACR_ | |
| BMP7 | Ubiquitylation | K178 | -0.107 | _IYK(gl)DYIR_ | |
| BMPR1A | Ubiquitylation | K232 | -0.391 | 0.172 | _TIAK(gl)QIQMVR_ |
| BMPR1A | Ubiquitylation | K477 | 0.265 | -0.134 | _EVVCVK(gl)R_ |
| DAB2 | Phosphorylation | S401 | -0.704 | -0.722 | _SSPNPFVGS(ph)PPK_ |
| RBPMS | Ubiquitylation | K60 | -0.903 | -0.103 | _LTSK(gl)QPVGFVSFDSR_ |
| TGFB1 | Ubiquitylation | K50 | -0.557 | _GQILSK(gl)LR_ | |
| TGFB3 | Ubiquitylation | K50 | -0.557 | _GQILSK(gl)LR_ | |
| TGFBR1 | Ubiquitylation | K449 | -0.991 | _VVCEQK(gl)LRPNIPNR_ | |
| TGFBR1 | Ubiquitylation | K502 | 0.553 | 0.430 | _TLSQLSQQEGIK(gl)M_ |
| TTK | Phosphorylation | S281 | 0.857 | 0.604 | _VPVNLLNS(ph)PDCDVK_ |
| TTK | Phosphorylation | S436 | -0.403 | -0.266 | _HTTFEQPVFSVSKQS(ph)PPISTSK_ |
| TTK | Phosphorylation | S821 | -1.037 | -0.693 | _YVLGQLVGLNS(ph)PNSILK_ |
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