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Query: DAB2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DAB2 0 -1.426 0.510 -0.470

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DAB2 Phosphorylation S401 -0.704 -0.722 _SSPNPFVGS(ph)PPK_

Background Information for DAB2:


Pubmed-DAB2 »
Uniprot-DAB2 »
Biogrid-DAB2 »
ProteomicsDB-DAB2 »

Tumorportal-DAB2 »
COSMIC-DAB2 »
GenomeRNAi-DAB2 »
Genecards-DAB2


Protein-protein Interactions for DAB2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTB Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait GAK Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PICALM Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC24C Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLC25A41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DAB2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PTB/PI_dom IPR006020 0


Protein complexes (CORUM database) featuring DAB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DAB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter Database 0.99
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0035091 phosphatidylinositol binding Database 0.62
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members Pathway Pathway_933 PID_TGFBR_PATHWAY 0 0.52
Category members GO Category GO:0060766 negative regulation of androgen receptor signaling pathway Database 0.35
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0030665 clathrin-coated vesicle membrane Database 0.24
Category members GO Category GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process Database 0.24
Category members GO Category GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation Database 0.23
Category members GO Category GO:0001934 positive regulation of protein phosphorylation Database 0.22
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0005905 coated pit Database 0.17
Category members GO Category GO:0010718 positive regulation of epithelial to mesenchymal transition Database 0.13
Category members GO Category GO:0006907 pinocytosis Database 0.11
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0005178 integrin binding Database 0.09
Category members GO Category GO:0005546 phosphatidylinositol-4,5-bisphosphate binding Database 0.09
Category members GO Category GO:0007588 excretion Database 0.08
Category members Pathway Pathway_1268 REACTOME_GAP_JUNCTION_DEGRADATION 0 0.08
Category members GO Category GO:0007257 activation of JUN kinase activity Database 0.08
Category members GO Category GO:0032091 negative regulation of protein binding Database 0.08
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0007492 endoderm development Database 0.06
Category members GO Category GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Database 0.06
Category members GO Category GO:0045785 positive regulation of cell adhesion Database 0.04
Category members GO Category GO:0001921 positive regulation of receptor recycling Database 0.02
Category members Pathway Pathway_1267 REACTOME_GAP_JUNCTION_TRAFFICKING 0 0
Category members GO Category GO:0000904 cell morphogenesis involved in differentiation Database 0
Category members GO Category GO:0006898 receptor-mediated endocytosis Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0030099 myeloid cell differentiation Database 0
Category members GO Category GO:0030132 clathrin coat of coated pit Database 0
Category members GO Category GO:0030276 clathrin binding Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0035612 AP-2 adaptor complex binding Database 0
Category members GO Category GO:0035615 clathrin adaptor activity Database 0
Category members GO Category GO:0045807 positive regulation of endocytosis Database 0
Category members GO Category GO:0046332 SMAD binding Database 0
Category members GO Category GO:0048268 clathrin coat assembly Database 0
Category members GO Category GO:0060391 positive regulation of SMAD protein import into nucleus Database 0
Category members GO Category GO:0070022 transforming growth factor beta receptor homodimeric complex Database 0


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