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negative regulation of androgen receptor signaling pathway
(GO:0060766)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HDAC1 1 -1.980 4.450
HDAC1 1 -1.980 4.450 -0.122 0.307 0.969 0.094 0.191
PIAS2 0 -0.510 0.250
PIAS2 0 -0.510 0.250 -1.034 -0.678 0.471 -0.051 1.019
PIAS2 0 -0.510 0.250
PIAS3 0 -1.170 1.310
SIRT1 0 0.910 -0.910
SMARCA4 0 -0.810 1.520 0.629 -0.158 0.141 0.337 0.333
DAB2 0 0.510 -0.470
PHB 0 -1.260 1.640 -0.429 0.649 -1.697

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
DAB2 Phosphorylation S401 -0.704 -0.722 _SSPNPFVGS(ph)PPK_
HDAC1 Ubiquitylation K50 0.036 _K(gl)MEIYRPHK_
HDAC1 Ubiquitylation K66 -0.593 _ANAEEMTK(gl)YHSDDYIK_
HDAC1 Ubiquitylation K74 0.620 -1.473 _YHSDDYIK(gl)FLR_
HDAC1 Ubiquitylation K89 0.749 -0.241 _SIRPDNMSEYSK(gl)QMQR_
HDAC1 Phosphorylation S393 -1.133 -1.144 _M(ox)LPHAPGVQM(ox)QAIPEDAIPEES(ph)GDEDEDDPDKR_
HDAC1 Phosphorylation S409 1.326 1.144 _ISICS(ph)SDKR_
HDAC1 Phosphorylation S410 1.326 1.144 _ISICS(ph)SDKR_
HDAC1 Ubiquitylation K412 0.642 -0.744 _ISICSSDK(gl)R_
PHB Ubiquitylation K83 -0.521 _NVPVITGSK(gl)DLQNVNITLR_
PHB Ubiquitylation K186 -0.124 _EFTEAVEAK(gl)QVAQQEAER_
PHB Ubiquitylation K202 0.125 _FVVEK(gl)AEQQKK_
PIAS2 Ubiquitylation K60 -1.191 _AGCSPAVQMKIK(gl)_
PIAS2 Ubiquitylation K331 -0.867 _VSLMCPLGK(gl)MR_
PIAS2 Ubiquitylation K341 -1.248 _VSLLCPLGK(gl)MR_
PIAS2 Ubiquitylation K452 -1.175 _IESSSVLSK(gl)PCSVTVASEASK_
PIAS2 Phosphorylation S490 -0.898 -0.944 _RTCPSLSPTS(ph)PLNNK_
PIAS2 Phosphorylation S505 0.198 -0.250 _GILSLPHQAS(ph)PVSR_
PIAS3 Ubiquitylation K331 -0.867 _VSLMCPLGK(gl)MR_
SIRT1 Phosphorylation S14 -0.369 -0.246 _(ac)ADEAALALQPGGS(ph)PSAAGADR_
SIRT1 Phosphorylation S16 -0.306 -1.665 _(ac)ADEAALALQPGGS(ph)PS(ph)AAGADREAASSPAGEPLR_
SIRT1 Phosphorylation S26 -1.047 -0.245 _EAAS(ph)SPAGEPLR_
SIRT1 Phosphorylation S27 0.351 -0.363 _EAASS(ph)PAGEPLR_
SIRT1 Phosphorylation S47 -0.574 -0.607 _S(ph)PGEPGGAAPER_
SIRT1 Ubiquitylation K238 -1.641 _RK(gl)DINTIEDAVK_
SIRT1 Ubiquitylation K499 -2.138 -0.204 _LGGEYAK(gl)LCCNPVK_
SIRT1 Ubiquitylation K578 -2.782 _GCMEEK(gl)PQEVQTSR_
SIRT1 Ubiquitylation K601 -3.051 _NVESIAEQMENPDLK(gl)NVGSSTGEK_
SMARCA4 Ubiquitylation K357 -0.934 _ITPIQK(gl)PR_
SMARCA4 Ubiquitylation K405 0.109 1.148 _ATIELK(gl)ALR_
SMARCA4 Ubiquitylation K437 -0.317 _DTALETALNAK(gl)AYKR_
SMARCA4 Ubiquitylation K455 0.225 _ITEK(gl)LEK_
SMARCA4 Ubiquitylation K496 0.923 _SVTGK(gl)IQK_
SMARCA4 Phosphorylation S677 -0.880 -0.324 _KAENAEGQTPAIGPDGEPLDETSQMS(ph)DLPVK_
SMARCA4 Ubiquitylation K1283 0.125 _ILAAAK(gl)YK_
SMARCA4 Phosphorylation S1413 -0.265 0.515 _EVDYSDS(ph)LTEK_
SMARCA4 Phosphorylation S1486 -0.713 -0.935 _LS(ph)PNPPNLTK_


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