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Query: PHB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PHB 0 0.288 -1.260 1.640 -0.429 0.649 -1.697

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PHB Ubiquitylation K202 0.125 _FVVEK(gl)AEQQKK_
PHB Ubiquitylation K186 -0.124 _EFTEAVEAK(gl)QVAQQEAER_
PHB Ubiquitylation K83 -0.521 _NVPVITGSK(gl)DLQNVNITLR_

Background Information for PHB:


Pubmed-PHB »
Uniprot-PHB »
Biogrid-PHB »
ProteomicsDB-PHB »

Tumorportal-PHB »
COSMIC-PHB »
GenomeRNAi-PHB »
Genecards-PHB


Protein-protein Interactions for PHB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AIFM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait AKAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM82A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MMGT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB11A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB2A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM109 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM63B Cat. description Hein, Mann, Cell 2015
Category members IP bait TMPO Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015
Category members IP bait YIPF5 Cat. description Hein, Mann, Cell 2015
Category members IP bait PHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YIPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PHB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Band_7 IPR001107 0


Protein complexes (CORUM database) featuring PHB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PHB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0010944 negative regulation of transcription by competitive promoter binding Database 0.59
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0060766 negative regulation of androgen receptor signaling pathway Database 0.35
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0030308 negative regulation of cell growth Database 0.18
Category members GO Category GO:0042826 histone deacetylase binding Database 0.16
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0071354 cellular response to interleukin-6 Database 0.1
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016575 histone deacetylation Database 0
Category members GO Category GO:0050847 progesterone receptor signaling pathway Database 0


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