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Query: PIAS3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PIAS3 0 0.443 -1.170 1.310

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PIAS3 Ubiquitylation K331 -0.867 _VSLMCPLGK(gl)MR_
PIAS3 Ubiquitylation K288 -1.088 _QLTAGTLLQK(gl)LR_

Background Information for PIAS3:


Pubmed-PIAS3 »
Uniprot-PIAS3 »
Biogrid-PIAS3 »
ProteomicsDB-PIAS3 »

Tumorportal-PIAS3 »
COSMIC-PIAS3 »
GenomeRNAi-PIAS3 »
Genecards-PIAS3


Protein-protein Interactions for PIAS3
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in PIAS3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SAP_dom IPR003034 1.96
Category members Znf_MIZ IPR004181 0.13


Protein complexes (CORUM database) featuring PIAS3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1831 PIAS3-SMAD3-P300 complex Database 0.07


Categories featuring PIAS3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members GO Category GO:0047485 protein N-terminus binding Database 1.84
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0033235 positive regulation of protein sumoylation Database 0.61
Category members Pathway Pathway_880 PID_AR_PATHWAY 0 0.58
Category members Pathway Pathway_845 PID_SMAD2_3NUCLEAR_PATHWAY 0 0.46
Category members GO Category GO:0016925 protein sumoylation Database 0.33
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0030425 dendrite Database 0.26
Category members Pathway Pathway_210 PID_CMYB_PATHWAY 0 0.2
Category members Pathway Pathway_447 KEGG_JAK_STAT_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0019789 SUMO ligase activity Database 0.05
Category members GO Category GO:0009725 response to hormone Database 0.01
Category members Pathway Pathway_1179 ST_STAT3_PATHWAY 0 0
Category members Pathway Pathway_166 ST_JAK_STAT_PATHWAY 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_283 KEGG_SMALL_CELL_LUNG_CANCER 0 0
Category members Pathway Pathway_652 PID_IL6_7_PATHWAY 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0015459 potassium channel regulator activity Database 0
Category members GO Category GO:0045838 positive regulation of membrane potential Database 0


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