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Results for the Category
KEGG_SMALL_CELL_LUNG_CANCER
(Pathway_283)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
AKT3 2 0.580 -0.030 -0.194
AKT3 2 0.580 -0.030
LAMB1 1 -0.210 0.090 -0.236 -0.180
PIK3R2 1 2.740 -1.180 0.269 0.348
CCND1 1 -1.820 3.470
TRAF2 1 -0.570 0.540
TRAF2 1 -0.570 0.540
LAMB2 1 -1.480 2.650
E2F2 0 0.670 -1.180
PIAS1 0 -1.020 1.720 -1.034 -0.678 0.471 -0.051 1.019
PIK3CB 0 -1.390 2.350
PIK3CB 0 -0.710 1.450
TRAF4 0 -0.140 0.360
PIAS2 0 -0.510 0.250
PIAS2 0 -0.510 0.250 -1.034 -0.678 0.471 -0.051 1.019
PIAS2 0 -0.510 0.250
PIAS3 0 -1.170 1.310
ITGA6 0 -0.530 0.420 -0.133 -0.561 -0.048
XIAP 0 0.600 -0.210
XIAP 0 0.600 -0.210 -1.128
IKBKB 0 0.400 0.610
CCNE1 0 0.460 -0.980
AKT2 0 -1.420 2.210 -0.194
PIAS4 0 -1.510 2.250 -1.454
CDK6 0 -0.190 0.160
CDK6 0 -0.190 0.160 -0.510 0.013
NFKB1 0 0.720 -0.810
BIRC2 0 -0.730 0.440
BIRC2 0 -0.730 0.440
E2F3 0 0.000 0.020
PIK3R3 0 -0.140 -0.480
PIK3R3 0 -0.140 -0.480 -0.441 0.147
PIK3CA 0
CDK2 0 -0.040 -0.300 -0.578 -0.797
CDK2 0 -0.040 -0.300 -0.202 -0.884 -0.107 -0.097 -0.501
MAX 0 -0.780 0.530 -0.276 0.290
MAX 0 -0.780 0.530
LAMA5 0 -1.280 1.860 1.257 0.402 0.337
TRAF3 0 -1.050 1.040
COL4A2 0 -0.170 0.350 -0.692 -0.297
CDK4 0 1.930 -0.950
CDK4 0 1.930 -0.950 -0.510 0.013
LAMC1 0 0.650 -1.240 -0.164 0.459
MYC 0 0.170 0.550 -2.443 -0.949 -0.454 -1.290
ITGAV 0 -0.297 -0.090 0.262
RB1 0 1.180 -1.070 0.429 0.755
RB1 0 1.180 -1.070
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
SKP2 0 0.030 0.690
SKP2 0 0.030 0.690
PIK3R1 0 1.910 -1.220 -0.441 0.147
ITGB1 0 0.390 -0.650 0.101 -0.036
ITGA2 0 -0.370 0.660 0.847 0.435
BCL2L1 0
BCL2 0 0.910 -0.740
CYCS 0 -0.020 -0.350 0.711 0.320
RELA 0 -1.130 1.600 0.793
CKS1B 0 -0.980 1.540
COL4A1 0 1.810 -1.260 -0.162
LAMA2 0 1.640 -0.040
LAMA2 0 1.640 -0.040 -0.260
RXRB 0 -0.900 1.680 -0.559
CHUK 0 -0.480

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
AKT2 Ubiquitylation K14 0.306 0.070 _EGWLHK(gl)R_
AKT2 Ubiquitylation K111 1.082 _AIQMVANSLK(gl)QR_
AKT2 Ubiquitylation K160 0.251 _LLGK(gl)GTFGK_
AKT2 Phosphorylation T451 -0.091 -0.612 _YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT2 Phosphorylation Y456 -0.265 _YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
AKT3 Ubiquitylation K14 0.306 0.070 _EGWLHK(gl)R_
AKT3 Ubiquitylation K14 4.941 5.277 _EGWVQK(gl)R_
AKT3 Ubiquitylation K111 1.082 _AIQMVANSLK(gl)QR_
AKT3 Phosphorylation S120 1.097 _MNCS(ph)PTSQIDNIGEEEMDASTTHHK_
AKT3 Ubiquitylation K160 0.251 _LLGK(gl)GTFGK_
AKT3 Phosphorylation T451 -0.091 -0.612 _YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT3 Phosphorylation Y456 -0.265 _YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
BCL2 Ubiquitylation K22 1.480 _YIHYK(gl)LSQR_
BCL2L1 Ubiquitylation K87 0.026 _EVIPMAAVK(gl)QALR_
BIRC2 Ubiquitylation K15 -0.259 0.307 _(ac)MEDSTILSDWTNSNK(gl)QK_
BIRC2 Ubiquitylation K17 -0.259 0.307 _(ac)MEDSTILSDWTNSNK(gl)QK_
BIRC2 Ubiquitylation K38 -0.069 _SIMEDSTILSDWTNSNKQK(gl)_
BIRC2 Ubiquitylation K102 -1.755 _LGDSPIQK(gl)HK_
BIRC2 Ubiquitylation K233 -0.511 _LSNWEPK(gl)DDAMSEHR_
BIRC2 Ubiquitylation K410 0.878 _DLVK(gl)QTVQSK_
BIRC2 Ubiquitylation K490 0.305 0.534 _ANVINK(gl)QEHDIIK_
BIRC2 Ubiquitylation K497 -1.934 _ANVINKQEHDIIK(gl)QK_
CCND1 Ubiquitylation K33 -0.490 _AMLK(gl)AEETCAPSVSYFK_
CCND1 Ubiquitylation K46 -1.016 -0.036 _AEETCAPSVSYFK(gl)CVQK_
CCND1 Ubiquitylation K95 -0.733 -0.137 _FLSLEPVK(gl)K_
CCND1 Ubiquitylation K96 -0.846 -0.155 _FLSLEPVKK(gl)_
CCND1 Ubiquitylation K238 0.245 _VIK(gl)CDPDCLR_
CCNE1 Phosphorylation S100 -0.765 _IIAPS(ph)RGSPLPVLSWANR_
CCNE1 Phosphorylation S103 -0.765 _IIAPS(ph)RGSPLPVLSWANR_
CCNE1 Phosphorylation S387 0.705 -0.922 _AS(ph)PLPSGLLTPPQSGK_
CDK2 Ubiquitylation K6 -0.130 -0.399 _(ac)MENFQK(gl)VEK_
CDK2 Ubiquitylation K6 0.011 -0.784 _(ac)M(ox)EDYTK(gl)IEK_
CDK2 Phosphorylation T14 0.429 _IGEGT(ph)YGVVYK_
CDK2 Phosphorylation Y15 0.697 0.743 _IGEGTY(ph)GVVYK_
CDK2 Ubiquitylation K20 0.272 _IGEGTYGVVYK(gl)AR_
CDK2 Ubiquitylation K20 -0.327 -0.270 _IGEGTYGVVYK(gl)GR_
CDK2 Ubiquitylation K24 0.366 _NK(gl)LTGEVVALKK_
CDK2 Ubiquitylation K33 0.033 _NKLTGEVVALK(gl)K_
CDK2 Ubiquitylation K33 0.736 0.239 _TTGQVVAMK(gl)K_
CDK2 Ubiquitylation K34 0.542 _LTGEVVALKK(gl)_
CDK2 Ubiquitylation K34 -0.306 _TTGQVVAMKK(gl)_
CDK2 Ubiquitylation K58 0.312 -0.262 _EISLLK(gl)ELR_
CDK2 Ubiquitylation K136 -0.468 _DLK(gl)PQNLLIDDK(gl)GTIK_
CDK2 Ubiquitylation K145 0.161 -0.954 _DLKPQNLLIDDK(gl)GTIK_
CDK2 Ubiquitylation K149 -0.038 _GTIK(gl)LADFGLAR_
CDK2 Ubiquitylation K251 -0.047 -1.236 _WK(gl)PGSLASHVK_
CDK2 Ubiquitylation K280 0.179 -1.210 _MLIYDPAK(gl)R_
CDK2 Ubiquitylation K298 -1.907 -2.380 _QDFSK(gl)VVPPLDEDGR_
CDK4 Ubiquitylation K142 -0.552 _DLK(gl)PENILVTSGGTVK_
CDK4 Ubiquitylation K211 -0.101 _K(gl)PLFCGNSEADQLGK_
CDK4 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4 Ubiquitylation K297 0.247 0.052 _ALQHSYLHK(gl)DEGNPE_
CDK4 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK4 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK4 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK4 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK4 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK4 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK4 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK4 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CDK6 Ubiquitylation K3 0.121 0.039 _(ac)MEK(gl)DGLCR_
CDK6 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK6 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK6 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK6 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK6 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK6 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK6 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK6 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CHUK Ubiquitylation K296 -1.637 _GGPVDLTLK(gl)QPR_
CKS1B Ubiquitylation K30 -0.426 -0.991 _DIAK(gl)LVPK_
CYCS Ubiquitylation K40 -2.265 _K(gl)TGQAPGYSYTAANK(gl)NK_
CYCS Ubiquitylation K54 -0.872 -1.922 _K(gl)TGQAPGYSYTAANK(gl)NK_
CYCS Ubiquitylation K56 -0.872 -1.922 _TGQAPGYSYTAANKNK(gl)_
CYCS Ubiquitylation K101 -1.859 _ADLIAYLKK(gl)_
E2F2 Ubiquitylation K188 -0.267 _TRYDTSLGLLTK(gl)K_
E2F2 Ubiquitylation K189 -0.267 _TRYDTSLGLLTK(gl)K_
E2F3 Ubiquitylation K188 -0.267 _TRYDTSLGLLTK(gl)K_
E2F3 Ubiquitylation K189 -0.267 _TRYDTSLGLLTK(gl)K_
IKBKB Ubiquitylation K106 0.253 _K(gl)YLNQFENCCGLR_
IKBKB Phosphorylation S672 0.670 0.244 _GPVSGS(ph)PDSMNASR_
ITGA6 Ubiquitylation K1116 0.715 _YIDNLEK(gl)K_
ITGA6 Ubiquitylation K1117 1.453 _YIDNLEKK(gl)_
ITGAV Ubiquitylation K233 0.373 _YDPNVYSIK(gl)YNNQLATR_
ITGAV Ubiquitylation K360 0.294 _ASGDFQTTK(gl)LNGFEVFAR_
ITGAV Ubiquitylation K923 0.636 _GK(gl)SAILYVK_
ITGB1 Ubiquitylation K774 0.402 _MNAK(gl)WDTGENPIYK_
ITGB1 Ubiquitylation K784 -0.172 0.350 _WDTGENPIYK(gl)SAVTTVVNPK_
ITGB1 Ubiquitylation K794 0.755 0.604 _SAVTTVVNPK(gl)YEGK_
LAMA2 Ubiquitylation K2038 -0.340 _LQAVK(gl)DKAR_
LAMA2 Ubiquitylation K2040 -0.340 _LQAVK(gl)DKAR_
LAMA5 Ubiquitylation K255 1.313 _EFTK(gl)ATNVR_
LAMB1 Ubiquitylation K182 2.294 _SSDFGK(gl)TWGVYR_
LAMB1 Ubiquitylation K207 1.047 _YFAYDCEASFPGISTGPMK(gl)K_
LAMB1 Ubiquitylation K208 1.047 _YFAYDCEASFPGISTGPMK(gl)K_
LAMB1 Ubiquitylation K239 -0.148 _ALDPAFK(gl)IEDPYSPR_
LAMB1 Ubiquitylation K253 0.823 _IQNLLK(gl)ITNLR_
LAMB1 Ubiquitylation K772 2.879 _SVVK(gl)TPMTDVCR_
LAMB2 Ubiquitylation K494 -0.943 _GTVPGSTPCDPNSGSCYCK(gl)R_
LAMB2 Ubiquitylation K1769 -0.028 _ALESK(gl)AAQLDGLEAR_
LAMC1 Ubiquitylation K564 0.404 _YFIAPAK(gl)FLGK_
MAX Phosphorylation S2 0.341 -0.060 _(ac)S(ph)DNDDIEVES(ph)DEEQPR_
MAX Phosphorylation S2 0.510 0.568 _(ac)S(ph)DNDDIEVESDADKR_
MAX Phosphorylation S11 0.341 -0.060 _(ac)S(ph)DNDDIEVES(ph)DEEQPR_
MAX Phosphorylation S11 -0.408 0.069 _(ac)S(ph)DNDDIEVES(ph)DADKR_
MAX Ubiquitylation K57 -0.903 0.246 _DSVPSLQGEK(gl)ASR_
MYC Phosphorylation S20 -1.444 -1.145 _PLNVS(ph)FTNR_
MYC Phosphorylation T72 -1.699 -1.813 _FELLPT(ph)PPLS(ph)PSRR_
MYC Phosphorylation S76 -1.777 -1.435 _FELLPTPPLS(ph)PSR_
MYC Phosphorylation S81 0.459 _S(ph)GLCSPSYVAVTPFSLR_
MYC Phosphorylation S85 0.199 0.073 _SGLCS(ph)PSYVAVTPFSLR_
MYC Ubiquitylation K162 -2.475 -1.259 _LVSEK(gl)LASYQAAR_
MYC Phosphorylation S295 -0.903 _SESGS(ph)PSAGGHSKPPHSPLVLK_
MYC Phosphorylation S307 -1.486 _SES(ph)GSPSAGGHSKPPHS(ph)PLVLK_
MYC Ubiquitylation K340 -2.449 _VK(gl)LDSVR_
MYC Ubiquitylation K403 -3.432 _DQIPELENNEK(gl)APK_
NFKB1 Phosphorylation S907 -0.025 0.113 _TTSQAHSLPLS(ph)PASTR_
PIAS1 Ubiquitylation K60 -1.191 _AGCSPAVQMKIK(gl)_
PIAS1 Ubiquitylation K341 -1.248 _VSLLCPLGK(gl)MR_
PIAS1 Phosphorylation S490 -0.898 -0.944 _RTCPSLSPTS(ph)PLNNK_
PIAS1 Phosphorylation S505 0.198 -0.250 _GILSLPHQAS(ph)PVSR_
PIAS2 Ubiquitylation K60 -1.191 _AGCSPAVQMKIK(gl)_
PIAS2 Ubiquitylation K331 -0.867 _VSLMCPLGK(gl)MR_
PIAS2 Ubiquitylation K341 -1.248 _VSLLCPLGK(gl)MR_
PIAS2 Ubiquitylation K452 -1.175 _IESSSVLSK(gl)PCSVTVASEASK_
PIAS2 Phosphorylation S490 -0.898 -0.944 _RTCPSLSPTS(ph)PLNNK_
PIAS2 Phosphorylation S505 0.198 -0.250 _GILSLPHQAS(ph)PVSR_
PIAS3 Ubiquitylation K331 -0.867 _VSLMCPLGK(gl)MR_
PIAS4 Ubiquitylation K57 0.068 -0.936 _ALQLVQFDCSPELFKK(gl)_
PIAS4 Ubiquitylation K125 -2.654 _LPAK(gl)TLKPEVR_
PIAS4 Ubiquitylation K330 -1.699 _VSLICPLVK(gl)MR_
PIK3CA Ubiquitylation K864 0.390 0.588 _NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA Ubiquitylation K868 0.204 0.651 _NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA Ubiquitylation K974 -0.273 _GAQECTK(gl)TREFER_
PIK3CB Ubiquitylation K1044 0.990 _SEEEALKQFKQK(gl)_
PIK3R2 Phosphorylation S262 -2.237 _APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2 Phosphorylation S263 -2.237 _APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2 Ubiquitylation K500 -0.189 _IFEEQGQTQEK(gl)CSK_
PIK3R2 Ubiquitylation K541 -0.609 _TK(gl)LEQQLR_
PIK3R2 Ubiquitylation K564 -0.431 -1.022 _MNSLK(gl)PDLMQLR_
PIK3R3 Ubiquitylation K226 -0.376 _YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3 Ubiquitylation K320 0.385 _LGEIHDSK(gl)MR_
RB1 Phosphorylation S69 -3.602 -3.397 _TAATAAAAAAEPPAPPPPPPPEEDPEQDS(ph)GPEDLPLVR_
RB1 Ubiquitylation K97 -0.546 _LK(gl)IPDHVR_
RB1 Phosphorylation T388 0.005 0.116 _TLQTDSIDSFETQRT(ph)PR_
RB1 Phosphorylation T405 -0.851 -0.901 _KSNLDEEVNVIPPHT(ph)PVR_
RB1 Phosphorylation S820 -0.019 _S(ph)PYKFPSSPLR_
RB1 Ubiquitylation K823 -2.214 _SPYK(gl)FPSSPLR_
RB1 Phosphorylation S827 0.824 0.111 _FPSS(ph)PLR_
RB1 Phosphorylation S839 -0.701 -1.045 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K842 -0.751 _IPGGNIYISPLK(gl)SPYK_
RB1 Phosphorylation S843 -0.701 -0.022 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K846 -2.084 _SPYK(gl)ISEGLPTPTK_
RB1 Phosphorylation T853 0.039 -0.555 _ISEGLPT(ph)PTKM(ox)T(ph)PR_
RB1 Ubiquitylation K856 -1.350 _ISEGLPTPTK(gl)MTPR_
RB1 Phosphorylation T858 -0.782 0.564 _ISEGLPT(ph)PTKMT(ph)PR_
RB1 Ubiquitylation K879 -0.187 _FQK(gl)INQMVCNSDR_
SKP2 Phosphorylation S8 -1.062 _SNLGHPES(ph)PPRK_
SKP2 Phosphorylation S64 -1.144 -1.189 _EEPDSENIPQELLSNLGHPES(ph)PPR_
SKP2 Phosphorylation S75 0.512 0.657 _SKGS(ph)DKDFVIVR_
SKP2 Ubiquitylation K228 -0.475 _LSDPIVNTLAK(gl)NSNLVR_
SKP2 Ubiquitylation K420 -1.178 _LTLQK(gl)PSCL_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_
TRAF2 Phosphorylation T7 -0.822 -1.190 _(ac)AAASVT(ph)PPGSLELLQPGFSK_
TRAF2 Ubiquitylation K27 -0.253 2.194 _TLLGTK(gl)LEAK_
TRAF2 Ubiquitylation K119 0.519 _GTLK(gl)EYESCHEGR_
TRAF2 Ubiquitylation K176 -1.233 1.022 _APCCGADVK(gl)AHHEVCPK_
TRAF2 Ubiquitylation K207 0.147 0.918 _FQDHVK(gl)TCGK_
TRAF2 Ubiquitylation K481 -0.507 0.417 _MEAK(gl)NSYVR_
TRAF3 Ubiquitylation K369 -1.061 -2.137 _VTELESVDK(gl)SAGQVAR_
TRAF4 Phosphorylation S426 0.249 _GS(ph)LDESSLGFGYPK_
XIAP Ubiquitylation K31 -0.312 -0.651 _LK(gl)TFANFPSGSPVSASTLAR_
XIAP Ubiquitylation K208 -0.788 -0.846 _LK(gl)NWEPCDR_
XIAP Ubiquitylation K358 -0.720 0.047 _TTEK(gl)TPSLTR_


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