bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: LAMB1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LAMB1 1 2.553 -0.210 0.090 -0.236 -0.180

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LAMB1 Ubiquitylation K772 2.879 _SVVK(gl)TPMTDVCR_
LAMB1 Ubiquitylation K182 2.294 _SSDFGK(gl)TWGVYR_
LAMB1 Ubiquitylation K207 1.047 _YFAYDCEASFPGISTGPMK(gl)K_
LAMB1 Ubiquitylation K208 1.047 _YFAYDCEASFPGISTGPMK(gl)K_
LAMB1 Ubiquitylation K253 0.823 _IQNLLK(gl)ITNLR_
LAMB1 Ubiquitylation K239 -0.148 _ALDPAFK(gl)IEDPYSPR_

Background Information for LAMB1:


Pubmed-LAMB1 »
Uniprot-LAMB1 »
Biogrid-LAMB1 »
ProteomicsDB-LAMB1 »

Tumorportal-LAMB1 »
COSMIC-LAMB1 »
GenomeRNAi-LAMB1 »
Genecards-LAMB1


Protein-protein Interactions for LAMB1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF11 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCAM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COLEC12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSG8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTPRK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINA12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LAMB1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EG-like_dom IPR000742 1.74
Category members t-SNARE IPR010989 0.04
Category members EGF_laminin IPR002049 0.04
Category members Laminin_N IPR008211 0
Category members Prefoldin IPR009053 0
Category members Laminin_IV IPR013015 0


Protein complexes (CORUM database) featuring LAMB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2318 ITGA6-ITGB4-Laminin10/12 complex Database 0


Categories featuring LAMB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members Pathway Pathway_1075 REACTOME_L1CAM_INTERACTIONS 0 1.32
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members Pathway Pathway_595 KEGG_FOCAL_ADHESION 0 1.08
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0005201 extracellular matrix structural constituent Database 0.55
Category members GO Category GO:0005578 proteinaceous extracellular matrix Database 0.53
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0050679 positive regulation of epithelial cell proliferation Database 0.5
Category members GO Category GO:0031012 extracellular matrix Database 0.45
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0034446 substrate adhesion-dependent cell spreading Database 0.26
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0005178 integrin binding Database 0.09
Category members Pathway Pathway_626 PID_A6B1_A6B4_INTEGRIN_PATHWAY 0 0.09
Category members GO Category GO:0042476 odontogenesis Database 0.09
Category members GO Category GO:0043259 laminin-10 complex Database 0.04
Category members Pathway Pathway_1027 PID_INTEGRIN1_PATHWAY 0 0
Category members Pathway Pathway_1290 PID_INTEGRIN4_PATHWAY 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_283 KEGG_SMALL_CELL_LUNG_CANCER 0 0
Category members Pathway Pathway_740 PID_INTEGRIN3_PATHWAY 0 0
Category members Pathway Pathway_922 KEGG_ECM_RECEPTOR_INTERACTION 0 0
Category members Pathway Pathway_930 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS 0 0
Category members GO Category GO:0005604 basement membrane Database 0
Category members GO Category GO:0005605 basal lamina Database 0
Category members GO Category GO:0005606 laminin-1 complex Database 0
Category members GO Category GO:0005607 laminin-2 complex Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007162 negative regulation of cell adhesion Database 0
Category members GO Category GO:0007566 embryo implantation Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0043208 glycosphingolipid binding Database 0
Category members GO Category GO:0043256 laminin complex Database 0


.

© Copyright Svejstrup Laboratory 2015