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Query: LAMB2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LAMB2 1 2.622 -1.480 2.650

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LAMB2 Ubiquitylation K1769 -0.028 _ALESK(gl)AAQLDGLEAR_
LAMB2 Ubiquitylation K494 -0.943 _GTVPGSTPCDPNSGSCYCK(gl)R_

Background Information for LAMB2:


Pubmed-LAMB2 »
Uniprot-LAMB2 »
Biogrid-LAMB2 »
ProteomicsDB-LAMB2 »

Tumorportal-LAMB2 »
COSMIC-LAMB2 »
GenomeRNAi-LAMB2 »
Genecards-LAMB2


Protein-protein Interactions for LAMB2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CRP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNAJC10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPHA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INSL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MMP26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NELL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLA2G10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLAUR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTPRK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB2A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIAE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLAMF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VWCE Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LAMB2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EG-like_dom IPR000742 1.74
Category members EGF_laminin IPR002049 0.04
Category members Laminin_N IPR008211 0
Category members Laminin_IV IPR013015 0


Protein complexes (CORUM database) featuring LAMB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2319 ITGA6-ITGB4-Laminin10/12 complex Database 0


Categories featuring LAMB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_595 KEGG_FOCAL_ADHESION 0 1.08
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0014044 Schwann cell development Database 0.62
Category members GO Category GO:0031012 extracellular matrix Database 0.45
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0005178 integrin binding Database 0.09
Category members Pathway Pathway_626 PID_A6B1_A6B4_INTEGRIN_PATHWAY 0 0.09
Category members GO Category GO:0050808 synapse organization Database 0.08
Category members GO Category GO:0045202 synapse Database 0.06
Category members Pathway Pathway_1027 PID_INTEGRIN1_PATHWAY 0 0
Category members Pathway Pathway_1290 PID_INTEGRIN4_PATHWAY 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_283 KEGG_SMALL_CELL_LUNG_CANCER 0 0
Category members Pathway Pathway_922 KEGG_ECM_RECEPTOR_INTERACTION 0 0
Category members Pathway Pathway_930 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS 0 0
Category members Disease phenotype Synaptic_congenital_myasthenic_syndromes Synaptic congenital myasthenic syndromes Database 0
Category members GO Category GO:0000904 cell morphogenesis involved in differentiation Database 0
Category members GO Category GO:0005604 basement membrane Database 0
Category members GO Category GO:0005605 basal lamina Database 0
Category members GO Category GO:0005608 laminin-3 complex Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007528 neuromuscular junction development Database 0
Category members GO Category GO:0007601 visual perception Database 0
Category members GO Category GO:0014002 astrocyte development Database 0
Category members GO Category GO:0043256 laminin complex Database 0
Category members GO Category GO:0043260 laminin-11 complex Database 0
Category members GO Category GO:0060041 retina development in camera-type eye Database 0


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