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Results for the Category
negative regulation of NF-kappaB transcription factor activity
(GO:0032088)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PSMD10 2 -1.900 3.850 0.390 2.518
CAT 2 2.260 -1.180 1.895 -0.238
ITCH 1 1.000 -0.610 -0.346 0.023 0.613
ARRB2 1 2.000 -1.160 -0.340 0.096 0.051 -1.604
RPS3 1 -0.940 1.360 0.247 -0.394 0.032 -0.254 -0.093
PELI1 1 -0.190 -0.210
UFL1 0 1.140 -1.070 0.912 0.837
CYLD 0 -1.250 2.010
SIRT1 0 0.910 -0.910
BMP7 0
SETD6 0 -0.570 1.220
DNAJA3 0 -0.010 -0.240 0.786 0.226 -0.161 -0.800 -0.347
PIAS4 0 -1.510 2.250 -1.454
CACTIN 0 -1.030 2.340 -0.337
TRIM37 0 0.060 0.540
DAP 0 0.240 -0.420
TNFAIP3 0 0.760 -0.500
RBCK1 0 -0.140 -0.340
TRAF3 0 -1.050 1.040
TRIM21 0 -0.230 -0.010 -0.266 -0.252
ZCCHC11 0 0.240 -0.330 1.006
ARRB1 0 0.960 -0.620
CDKN2A 0 -0.080 -0.260 -0.556 -1.080 -3.270 -1.110
OTULIN 0 -0.520 0.500
GFI1 0 0.150 0.340
BRMS1 0 -0.780 0.690
SIVA1 0 1.120 -0.430
CHP1 0 0.130 0.190 -0.105 0.192
USP7 0 -0.600 0.590
USP7 0 -0.600 0.590 0.789 -0.077 0.319 -0.125 0.108
COMMD6 0 0.220 -0.750

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ARRB1 Phosphorylation S412 0.138 0.253 _GMKDDKEEEEDGTGS(ph)PQLNNR_
ARRB2 Ubiquitylation K199 -1.933 _VQFAPEK(gl)PGPQPSAETTR_
BMP7 Ubiquitylation K178 -0.107 _IYK(gl)DYIR_
BRMS1 Ubiquitylation K133 0.186 _NK(gl)YECELQGAK_
COMMD6 Ubiquitylation K54 0.001 _SLK(gl)YPYVAVMLK_
CYLD Ubiquitylation K114 -1.068 0.927 _FSLFK(gl)NR_
DAP Phosphorylation S2 -0.404 1.136 _(ac)S(ph)SPPEGKLETK_
DAP Phosphorylation S3 -0.404 1.254 _(ac)SS(ph)PPEGKLETK_
DAP Phosphorylation S51 -0.968 0.151 _DKDDQEWESPS(ph)PPKPTVFISGVIAR_
GFI1 Phosphorylation S68 0.285 0.145 _DRLS(ph)PESQLTEAPDR_
ITCH Ubiquitylation K66 -0.890 _WK(gl)QPLTVIVTPVSK_
ITCH Ubiquitylation K350 0.049 0.396 _VYYVDHVEK(gl)R_
ITCH Ubiquitylation K446 -1.514 -1.539 _EFDPLGPLPPGWEK(gl)R_
ITCH Ubiquitylation K478 -1.265 _SQGQLNEK(gl)PLPEGWEMR_
ITCH Ubiquitylation K513 -0.564 1.593 _TGK(gl)SALDNGPQIAYVR_
ITCH Ubiquitylation K861 -0.810 0.596 _VGK(gl)ENWLPR_
OTULIN Ubiquitylation K64 -0.645 _AADEIEK(gl)EKELLIHER_
OTULIN Ubiquitylation K66 -0.645 _AADEIEK(gl)EKELLIHER_
OTULIN Ubiquitylation K94 -0.031 -0.564 _LSVAPEMDIMDYCKK(gl)_
PELI1 Ubiquitylation K12 -0.817 _(ac)MFSPDQENHPSK(gl)APVK_
PELI1 Ubiquitylation K172 1.788 0.291 _NIFLGEKAAK(gl)_
PIAS4 Ubiquitylation K57 0.068 -0.936 _ALQLVQFDCSPELFKK(gl)_
PIAS4 Ubiquitylation K125 -2.654 _LPAK(gl)TLKPEVR_
PIAS4 Ubiquitylation K330 -1.699 _VSLICPLVK(gl)MR_
PSMD10 Ubiquitylation K30 0.195 0.473 _LEELKESILADK(gl)SLATR_
PSMD10 Ubiquitylation K221 0.332 _GGLGLILK(gl)R_
RBCK1 Ubiquitylation K158 -0.966 -0.114 _MLEDLGFK(gl)DLTLQPR_
RBCK1 Ubiquitylation K254 -0.492 0.424 _K(gl)QQQQEGNYLQHVQLDQR_
RBCK1 Ubiquitylation K342 -0.827 -0.164 _EIK(gl)ALLTPEDYQR_
RPS3 Ubiquitylation K7 -0.351 0.640 _(ac)AVQISK(gl)K(gl)R_
RPS3 Ubiquitylation K8 -0.271 0.892 _(ac)AVQISK(gl)K(gl)R_
RPS3 Ubiquitylation K10 -0.280 0.954 _K(gl)FVADGIFK_
RPS3 Ubiquitylation K62 0.377 1.170 _TQNVLGEK(gl)GRR_
RPS3 Ubiquitylation K75 0.306 0.997 _IRELTAVVQK(gl)R_
RPS3 Ubiquitylation K90 0.875 0.887 _FGFPEGSVELYAEK(gl)VATR_
RPS3 Ubiquitylation K132 2.406 1.406 _FIMESGAK(gl)GCEVVVSGK_
RPS3 Ubiquitylation K141 0.299 1.362 _GCEVVVSGK(gl)LR_
RPS3 Ubiquitylation K185 1.424 _QGVLGIK(gl)VK_
RPS3 Ubiquitylation K197 -0.785 0.209 _IMLPWDPTGK(gl)_
RPS3 Ubiquitylation K202 -0.633 _K(gl)PLPDHVSIVEPK_
RPS3 Phosphorylation T220 -0.052 -0.022 _DEILPT(ph)TPISEQK_
RPS3 Phosphorylation T221 -0.107 0.074 _DEILPTT(ph)PISEQK_
RPS3 Ubiquitylation K230 1.186 -0.281 _GGK(gl)PEPPAM(ox)PQPVPTA_
SETD6 Ubiquitylation K327 -0.155 _EAALQGTK(gl)TEAER_
SIRT1 Phosphorylation S14 -0.369 -0.246 _(ac)ADEAALALQPGGS(ph)PSAAGADR_
SIRT1 Phosphorylation S16 -0.306 -1.665 _(ac)ADEAALALQPGGS(ph)PS(ph)AAGADREAASSPAGEPLR_
SIRT1 Phosphorylation S26 -1.047 -0.245 _EAAS(ph)SPAGEPLR_
SIRT1 Phosphorylation S27 0.351 -0.363 _EAASS(ph)PAGEPLR_
SIRT1 Phosphorylation S47 -0.574 -0.607 _S(ph)PGEPGGAAPER_
SIRT1 Ubiquitylation K238 -1.641 _RK(gl)DINTIEDAVK_
SIRT1 Ubiquitylation K499 -2.138 -0.204 _LGGEYAK(gl)LCCNPVK_
SIRT1 Ubiquitylation K578 -2.782 _GCMEEK(gl)PQEVQTSR_
SIRT1 Ubiquitylation K601 -3.051 _NVESIAEQMENPDLK(gl)NVGSSTGEK_
SIVA1 Ubiquitylation K17 -1.914 _SCPFADVAPLQLK(gl)VR_
SIVA1 Ubiquitylation K41 0.271 -0.229 _YSQEVFEK(gl)TKR_
SIVA1 Ubiquitylation K43 -0.412 1.388 _YSQEVFEK(gl)TKR_
SIVA1 Ubiquitylation K124 0.062 _AVDGK(gl)AVCGQCER_
TNFAIP3 Ubiquitylation K722 0.496 0.176 _ASCK(gl)NILACR_
TRAF3 Ubiquitylation K369 -1.061 -2.137 _VTELESVDK(gl)SAGQVAR_
TRIM37 Ubiquitylation K679 -0.977 -0.642 _LK(gl)TQMAEVR_
TRIM37 Ubiquitylation K693 -1.498 -0.586 _TDVK(gl)NTLSEIK_
USP7 Phosphorylation S18 -0.616 -0.581 _AGEQQLS(ph)EPEDM(ox)EM(ox)EAGDTDDPPR_
USP7 Ubiquitylation K158 -0.447 0.111 _IINYRDDEK(gl)SFSR_
USP7 Ubiquitylation K264 -1.350 _AVYMMPTEGDDSSK(gl)SVPLALQR_
USP7 Ubiquitylation K430 0.500 _FMYDPQTDQNIK(gl)INDR_
USP7 Ubiquitylation K605 1.273 _YTVFK(gl)VLK_
USP7 Ubiquitylation K834 -0.068 0.064 _MNYFQVAK(gl)TVAQR_
USP7 Ubiquitylation K879 -0.271 _DLLQFFK(gl)PR_
USP7 Ubiquitylation K892 0.402 0.347 _KLYYQQLK(gl)MK_
USP7 Ubiquitylation K894 0.380 _MK(gl)ITDFENRR_
USP7 Ubiquitylation K944 0.512 0.702 _KAVELGEK(gl)ASGK_
USP7 Ubiquitylation K1106 0.275 0.509 _YTYLEK(gl)AIK_
ZCCHC11 Phosphorylation S104 0.102 _KFPNS(ph)PVK_
ZCCHC11 Phosphorylation S155 0.940 0.682 _SEKVPS(ph)SPAEAEKGPSLLLK_
ZCCHC11 Phosphorylation S156 0.940 0.043 _SEKVPSS(ph)PAEAEKGPSLLLK_
ZCCHC11 Ubiquitylation K680 -1.370 -0.706 _IAIEDPFSVK(gl)R_


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