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Query: CACTIN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CACTIN 0 2.003 -1.030 2.340 -0.337

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CACTIN:


Pubmed-CACTIN »
Uniprot-CACTIN »
Biogrid-CACTIN »
ProteomicsDB-CACTIN »

Tumorportal-CACTIN »
COSMIC-CACTIN »
GenomeRNAi-CACTIN »
Genecards-CACTIN


Protein-protein Interactions for CACTIN
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CRNKL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ISY1;RAB43 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMEK1 Cat. description Hein, Mann, Cell 2015


Protein Domains in CACTIN
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CACTIN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1181 C complex spliceosome Database 2.39


Categories featuring CACTIN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0001933 negative regulation of protein phosphorylation Database 0.04
Category members GO Category GO:0032088 negative regulation of NF-kappaB transcription factor activity Database 0.04
Category members GO Category GO:0032717 negative regulation of interleukin-8 production Database 0.04
Category members GO Category GO:0071356 cellular response to tumor necrosis factor Database 0.03
Category members GO Category GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway Database 0
Category members GO Category GO:0032688 negative regulation of interferon-beta production Database 0
Category members GO Category GO:0032720 negative regulation of tumor necrosis factor production Database 0
Category members GO Category GO:0034122 negative regulation of toll-like receptor signaling pathway Database 0
Category members GO Category GO:0060339 negative regulation of type I interferon-mediated signaling pathway Database 0
Category members GO Category GO:0071222 cellular response to lipopolysaccharide Database 0
Category members GO Category GO:0071347 cellular response to interleukin-1 Database 0


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