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Query: DNAJA3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DNAJA3 0 -0.296 -0.010 -0.240 0.786 0.226 -0.161 -0.800 -0.347

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for DNAJA3:


Pubmed-DNAJA3 »
Uniprot-DNAJA3 »
Biogrid-DNAJA3 »
ProteomicsDB-DNAJA3 »

Tumorportal-DNAJA3 »
COSMIC-DNAJA3 »
GenomeRNAi-DNAJA3 »
Genecards-DNAJA3


Protein-protein Interactions for DNAJA3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPF Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP4C Cat. description Hein, Mann, Cell 2015
Category members IP bait S100A4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHRM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THBS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DNAJA3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DnaJ_domain IPR001623 0.3
Category members HSP_DnaJ_Cys-rich_dom IPR001305 0
Category members DnaJ_C IPR002939 0
Category members HSP40/DnaJ_pept-bd IPR008971 0


Protein complexes (CORUM database) featuring DNAJA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DNAJA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0031072 heat shock protein binding Database 1.59
Category members GO Category GO:0042645 mitochondrial nucleoid Database 0.61
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0051059 NF-kappaB binding Database 0.25
Category members GO Category GO:0006924 activation-induced cell death of T cells Database 0.16
Category members GO Category GO:0008385 IkappaB kinase complex Database 0.13
Category members GO Category GO:0030544 Hsp70 protein binding Database 0.1
Category members GO Category GO:0005884 actin filament Database 0.08
Category members GO Category GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process Database 0.08
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0033256 I-kappaB/NF-kappaB complex Database 0.08
Category members GO Category GO:0045211 postsynaptic membrane Database 0.06
Category members GO Category GO:0050821 protein stabilization Database 0.04
Category members GO Category GO:0042102 positive regulation of T cell proliferation Database 0.04
Category members GO Category GO:0005133 interferon-gamma receptor binding Database 0.04
Category members GO Category GO:0032088 negative regulation of NF-kappaB transcription factor activity Database 0.04
Category members Pathway Pathway_644 PID_TRKR_PATHWAY 0 0.04
Category members GO Category GO:0033077 T cell differentiation in thymus Database 0.03
Category members GO Category GO:0019897 extrinsic to plasma membrane Database 0.03
Category members GO Category GO:0007569 cell aging Database 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_882 BIOCARTA_TID_PATHWAY 0 0
Category members GO Category GO:0005083 small GTPase regulator activity Database 0
Category members GO Category GO:0006264 mitochondrial DNA replication Database 0
Category members GO Category GO:0006469 negative regulation of protein kinase activity Database 0
Category members GO Category GO:0007005 mitochondrion organization Database 0
Category members GO Category GO:0007528 neuromuscular junction development Database 0
Category members GO Category GO:0009408 response to heat Database 0
Category members GO Category GO:0009790 embryo development Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0030971 receptor tyrosine kinase binding Database 0
Category members GO Category GO:0031398 positive regulation of protein ubiquitination Database 0
Category members GO Category GO:0031594 neuromuscular junction Database 0
Category members GO Category GO:0034341 response to interferon-gamma Database 0
Category members GO Category GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway Database 0
Category members GO Category GO:0071340 skeletal muscle acetylcholine-gated channel clustering Database 0


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