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Query: PELI1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PELI1 1 2.079 -0.190 -0.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PELI1 Ubiquitylation K172 1.788 0.291 _NIFLGEKAAK(gl)_
PELI1 Ubiquitylation K12 -0.817 _(ac)MFSPDQENHPSK(gl)APVK_

Background Information for PELI1:


Pubmed-PELI1 »
Uniprot-PELI1 »
Biogrid-PELI1 »
ProteomicsDB-PELI1 »

Tumorportal-PELI1 »
COSMIC-PELI1 »
GenomeRNAi-PELI1 »
Genecards-PELI1


Protein-protein Interactions for PELI1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MDM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PELI1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Pellino_fam IPR006800 0


Protein complexes (CORUM database) featuring PELI1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PELI1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members Pathway Pathway_975 REACTOME_IL1_SIGNALING 0 0.42
Category members GO Category GO:0032496 response to lipopolysaccharide Database 0.35
Category members GO Category GO:0043331 response to dsRNA Database 0.34
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members GO Category GO:0034142 toll-like receptor 4 signaling pathway Database 0.27
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members Pathway Pathway_826 REACTOME_ACTIVATED_TLR4_SIGNALLING 0 0.21
Category members Pathway Pathway_527 REACTOME_TOLL_RECEPTOR_CASCADES 0 0.17
Category members Pathway Pathway_797 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION 0 0.12
Category members GO Category GO:0002224 toll-like receptor signaling pathway Database 0.12
Category members Pathway Pathway_814 REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE 0 0.05
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0001819 positive regulation of cytokine production Database 0.05
Category members GO Category GO:0032088 negative regulation of NF-kappaB transcription factor activity Database 0.04
Category members GO Category GO:0034146 toll-like receptor 5 signaling pathway Database 0.04
Category members GO Category GO:0034166 toll-like receptor 10 signaling pathway Database 0.04
Category members GO Category GO:0050871 positive regulation of B cell activation Database 0.04
Category members Pathway Pathway_1052 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX 0 0.04
Category members GO Category GO:0034162 toll-like receptor 9 signaling pathway Database 0.04
Category members GO Category GO:0034134 toll-like receptor 2 signaling pathway Database 0.01
Category members Pathway Pathway_504 REACTOME_SIGNALING_BY_ILS 0 0
Category members GO Category GO:0002755 MyD88-dependent toll-like receptor signaling pathway Database 0
Category members GO Category GO:0008063 Toll signaling pathway Database 0
Category members GO Category GO:0030890 positive regulation of B cell proliferation Database 0
Category members GO Category GO:0031398 positive regulation of protein ubiquitination Database 0
Category members GO Category GO:0034141 positive regulation of toll-like receptor 3 signaling pathway Database 0
Category members GO Category GO:0034145 positive regulation of toll-like receptor 4 signaling pathway Database 0
Category members GO Category GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway Database 0
Category members GO Category GO:0038124 toll-like receptor TLR6:TLR2 signaling pathway Database 0
Category members GO Category GO:0042130 negative regulation of T cell proliferation Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0050868 negative regulation of T cell activation Database 0
Category members GO Category GO:0070936 protein K48-linked ubiquitination Database 0


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