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Results for the Category
MyD88-dependent toll-like receptor signaling pathway
(GO:0002755)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RPS27A 4 -1.330 2.560 -0.309 0.131 -0.009
UBC 3 -0.309 0.131 -0.009
UBC 3
UBC 3
UBB 3 -0.309 0.131 -0.009
JUN 3 -0.930 0.930 -0.126
UBA52 3 -1.260 2.180 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180
MAPK14 2 -0.160 -0.350
ATF2 2 -1.380 1.800
TAB3 2 -0.550 1.560 0.022 -0.207
TAB3 2 -0.550 1.560
MAPK9 1 0.110 -0.490
TAB1 1 1.890 -0.670
TAB1 1 1.890 -0.670 1.657
RIPK2 1 -1.740 3.580
PPP2R5D 1 -0.110 0.620
PPP2R5D 1 -0.110 0.620 -0.455 -0.019
PELI2 1 -0.150 0.600
MAP2K1 1 -1.590 2.780
RPS6KA3 1 -1.550 2.890
PELI1 1 -0.190 -0.210
MAP2K3 0 0.780 -0.600
TAB2 0 -0.030 -0.580
MAP2K4 0 -0.300 0.320
MEF2A 0 0.820 -0.530
MEF2A 0 0.820 -0.530
IKBKG 0
MAP2K7 0 0.180 -0.660 -2.110
NFKB2 0 1.750 -0.820
MEF2C 0 -0.980 1.550
MEF2C 0 -0.980 1.550
MAP3K1 0 0.750 -1.270
MAPK3 0
IKBKB 0 0.400 0.610
DUSP3 0 0.360 -0.500
MAP2K6 0 1.270 -0.780
NFKB1 0 0.720 -0.810
RPS6KA1 0 -0.160 -0.660
RPS6KA1 0 -0.160 -0.660
CREB1 0 1.080 -0.800 -1.027
ATF1 0 0.500 0.320 -0.601 0.001
ELK1 0
MAP2K2 0 -0.610 0.080
MAP2K2 0 -0.610 0.080
MAP3K7 0 -1.120 1.140 -1.048
HSPD1 0 1.020 -0.650 1.151 0.719 -0.757
TNIP1 0 1.510 -0.910
TNIP1 0 1.510 -0.910
CDK1 0 -0.370 0.080 -0.202 -0.884 -0.107 -0.097 -0.501
RELA 0 -1.130 1.600 0.793
CHUK 0 -0.480
UBE2V1 0 -0.460 -0.280
UBE2V1 0 0.870 -1.000
UBE2V1 0 -0.460 -0.280
UBE2V1 0 0.870 -1.000
UBE2V1 0 -0.460 -0.280
UBE2V1 0 0.870 -1.000

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATF1 Phosphorylation S464 0.128 _TTPSATSLPQTVVMTS(ph)PVTLTSQTTK_
ATF1 Ubiquitylation K481 -0.754 _TDDPQLK(gl)R_
ATF1 Ubiquitylation K505 0.609 0.811 _EYVK(gl)CLENR_
ATF2 Phosphorylation T71 -1.263 -1.166 _NDSVIVADQTPT(ph)PTR_
ATF2 Phosphorylation S90 2.624 2.389 _NCEEVGLFNELAS(ph)PFENEFKK_
ATF2 Phosphorylation S112 1.025 1.118 _MPLDLS(ph)PLATPIIR_
CDK1 Ubiquitylation K6 0.011 -0.784 _(ac)M(ox)EDYTK(gl)IEK_
CDK1 Ubiquitylation K20 -0.327 -0.270 _IGEGTYGVVYK(gl)GR_
CDK1 Ubiquitylation K33 0.736 0.239 _TTGQVVAMK(gl)K_
CDK1 Ubiquitylation K34 -0.306 _TTGQVVAMKK(gl)_
CDK1 Ubiquitylation K58 0.312 -0.262 _EISLLK(gl)ELR_
CDK1 Ubiquitylation K136 -0.468 _DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K145 0.161 -0.954 _DLKPQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K149 -0.038 _GTIK(gl)LADFGLAR_
CDK1 Ubiquitylation K251 -0.047 -1.236 _WK(gl)PGSLASHVK_
CDK1 Ubiquitylation K280 0.179 -1.210 _MLIYDPAK(gl)R_
CHUK Ubiquitylation K296 -1.637 _GGPVDLTLK(gl)QPR_
CREB1 Phosphorylation S271 -0.979 -1.450 _TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1 Ubiquitylation K333 1.343 _ALK(gl)DLYCHK_
DUSP3 Ubiquitylation K116 -0.586 _AADFIDQALAQK(gl)NGR_
ELK1 Phosphorylation S273 -0.601 -0.553 _PAVVLPSAAPAGAAAPPS(ph)GSR_
ELK1 Phosphorylation S275 -0.601 -0.553 _PAVVLPSAAPAGAAAPPS(ph)GSR_
ELK1 Phosphorylation S403 0.568 -0.579 _DLELPLS(ph)PSLLGGPGPER_
HSPD1 Phosphorylation S70 0.210 0.487 _TVIIEQSWGS(ph)PK_
HSPD1 Ubiquitylation K82 -0.300 _DGVTVAK(gl)SIDLK_
HSPD1 Ubiquitylation K87 -0.005 0.292 _SIDLK(gl)DKYK_
HSPD1 Ubiquitylation K130 -0.428 _EGFEK(gl)ISK_
HSPD1 Ubiquitylation K233 0.853 0.024 _GYISPYFINTSK(gl)GQK_
HSPD1 Ubiquitylation K292 0.339 _LK(gl)VGLQVVAVK_
IKBKB Ubiquitylation K106 0.253 _K(gl)YLNQFENCCGLR_
IKBKB Phosphorylation S672 0.670 0.244 _GPVSGS(ph)PDSMNASR_
IKBKG Ubiquitylation K285 -1.202 -0.389 _QEVIDKLK(gl)EEAEQHK_
IKBKG Ubiquitylation K309 0.123 0.725 _AQADIYK(gl)ADFQAER_
IKBKG Ubiquitylation K344 0.060 _LK(gl)ASCQESAR_
IKBKG Phosphorylation S387 -1.270 -1.418 _S(ph)PPEEPPDFCCPK_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
MAP2K1 Ubiquitylation K192 -0.205 -0.241 _DVK(gl)PSNILVNSR_
MAP2K1 Phosphorylation S385 0.066 _RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1 Phosphorylation T386 0.377 _RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2 Phosphorylation S23 0.873 0.258 _RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2 Phosphorylation T25 0.439 _RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2 Ubiquitylation K192 -0.205 -0.241 _DVK(gl)PSNILVNSR_
MAP2K2 Phosphorylation S293 -0.361 _ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2 Phosphorylation S295 -0.234 0.026 _ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2 Phosphorylation T394 0.570 0.158 _LNQPGT(ph)PTR_
MAP2K3 Ubiquitylation K84 0.045 -0.277 _GAYGVVEK(gl)VR_
MAP2K3 Ubiquitylation K232 -1.394 _TMDAGCK(gl)PYMAPER_
MAP2K3 Ubiquitylation K247 0.065 -0.737 _INPELNQK(gl)GYNVK_
MAP2K4 Phosphorylation S80 0.441 _LRTHS(ph)IESSGK_
MAP2K6 Phosphorylation T28 -1.813 -0.792 _EAFEQPQTSST(ph)PPRDLDSK_
MAP2K6 Ubiquitylation K232 0.220 _INPELNQK(gl)GYSVK_
MAP2K7 Ubiquitylation K9 -1.406 _(ac)AASSLEQK(gl)LSR_
MAP2K7 Ubiquitylation K300 -1.228 _GQIK(gl)LCDFGISGR_
MAP2K7 Ubiquitylation K442 -1.326 _DVMAK(gl)TESPR_
MAP3K1 Phosphorylation S292 0.209 _RAPS(ph)PDGFSPYSPEETNR_
MAP3K1 Phosphorylation S506 1.427 _SHDFYSHELS(ph)SPVDSPSSLR_
MAP3K1 Phosphorylation S507 1.436 _SHDFYSHELSS(ph)PVDSPSSLR_
MAP3K1 Phosphorylation S923 0.127 -0.120 _LSAS(ph)SEDISER_
MAP3K7 Phosphorylation S374 0.149 -0.337 _GS(ph)SVESLPPTSEGK_
MAP3K7 Phosphorylation S375 0.171 -0.087 _GSS(ph)VESLPPTSEGK_
MAP3K7 Phosphorylation S389 1.072 1.445 _RMS(ph)ADMSEIEAR_
MAP3K7 Phosphorylation S439 0.246 0.198 _S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7 Ubiquitylation K474 -0.385 -0.242 _MITTSGPTSEK(gl)PTR_
MAP3K7 Ubiquitylation K589 -0.104 _SLSTYYQQCK(gl)K_
MAP3K7 Ubiquitylation K590 -0.551 0.560 _K(gl)QLEVIR_
MAPK14 Phosphorylation S2 3.221 3.623 _(ac)S(ph)QERPTFYR_
MAPK14 Phosphorylation T180 0.958 1.087 _HTDDEM(ox)T(ph)GYVATR_
MAPK14 Phosphorylation Y182 1.388 1.374 _HTDDEM(ox)TGY(ph)VATR_
MAPK14 Ubiquitylation K249 0.073 -1.380 _LVGTPGAELLKK(gl)_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_
MEF2A Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2A Phosphorylation S235 0.664 -0.092 _AS(ph)PNLIGATGANSLGK_
MEF2A Phosphorylation T253 -1.271 _VMPT(ph)KSPPPPGGGNLGMNSR_
MEF2A Phosphorylation S255 -1.235 _VMPTKS(ph)PPPPGGGNLGMNSR_
MEF2A Phosphorylation S408 -0.173 -0.049 _SEPIS(ph)PPRDR_
MEF2A Phosphorylation S494 -0.858 -1.232 _GDFHSPIVLGRPPNTEDRES(ph)PSVK_
MEF2C Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2C Phosphorylation S240 0.008 0.302 _NS(ph)PGLLVSPGNLNK_
MEF2C Phosphorylation S406 0.272 0.338 _SEPVS(ph)PPRDR_
NFKB1 Phosphorylation S907 -0.025 0.113 _TTSQAHSLPLS(ph)PASTR_
NFKB2 Ubiquitylation K741 -2.393 _GHTPLDLTCSTK(gl)VK_
NFKB2 Ubiquitylation K743 -0.624 _GHTPLDLTCSTKVK(gl)_
PELI1 Ubiquitylation K12 -0.817 _(ac)MFSPDQENHPSK(gl)APVK_
PELI1 Ubiquitylation K172 1.788 0.291 _NIFLGEKAAK(gl)_
PELI2 Ubiquitylation K172 1.788 0.291 _NIFLGEKAAK(gl)_
PPP2R5D Phosphorylation T63 -1.449 _RPSNST(ph)PPPTQLSK_
PPP2R5D Ubiquitylation K232 -0.302 _FLESPDFQPNIAK(gl)K_
PPP2R5D Ubiquitylation K233 -0.302 0.665 _FLESPDFQPNIAKK(gl)_
PPP2R5D Ubiquitylation K409 -0.010 _QLAK(gl)CVSSPHFQVAER_
PPP2R5D Phosphorylation S573 0.524 0.357 _RKS(ph)ELPQDVYTIK_
PPP2R5D Phosphorylation S598 -0.317 1.858 _RAEEFLTAS(ph)QEAL_
RIPK2 Ubiquitylation K410 -2.810 _AAFCDHK(gl)TTPCSSAIINPLSTAGNSER_
RIPK2 Phosphorylation S531 0.884 0.839 _SPS(ph)LNLLQNK_
RIPK2 Ubiquitylation K538 -2.659 _SPSLNLLQNK(gl)SM_
RPS27A Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
RPS27A Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
RPS27A Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
RPS27A Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
RPS27A Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
RPS27A Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
RPS27A Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
RPS27A Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
RPS27A Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
RPS27A Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
RPS6KA1 Phosphorylation S227 0.363 0.496 _AYS(ph)FCGTVEYM(ox)APEVVNR_
RPS6KA1 Phosphorylation T231 0.315 _KAYSFCGT(ph)VEYMAPEVVNR_
RPS6KA1 Ubiquitylation K316 -1.156 _LGSGPDGAEEIK(gl)R_
RPS6KA1 Phosphorylation T359 -0.149 -0.339 _T(ph)PKDSPGIPPSAGAHQLFR_
RPS6KA1 Phosphorylation S363 -0.711 -0.697 _TPKDS(ph)PGIPPSAGAHQLFR_
RPS6KA1 Ubiquitylation K566 -0.152 _ICDFGFAK(gl)QLR_
RPS6KA3 Phosphorylation S227 0.363 0.496 _AYS(ph)FCGTVEYM(ox)APEVVNR_
RPS6KA3 Phosphorylation T231 0.315 _KAYSFCGT(ph)VEYMAPEVVNR_
RPS6KA3 Ubiquitylation K322 -0.076 -0.376 _LGAGPDGVEEIK(gl)R_
RPS6KA3 Phosphorylation T365 -0.892 -1.003 _T(ph)PKDSPGIPPSANAHQLFR_
RPS6KA3 Phosphorylation S369 -0.621 -0.862 _TPKDS(ph)PGIPPSANAHQLFR_
RPS6KA3 Ubiquitylation K566 -0.152 _ICDFGFAK(gl)QLR_
RPS6KA3 Phosphorylation S715 -0.923 -0.880 _NQS(ph)PVLEPVGR_
TAB1 Phosphorylation S7 -0.170 0.140 _S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_
TAB1 Phosphorylation S16 -0.138 0.069 _SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_
TAB1 Ubiquitylation K186 -1.015 _SYSADGK(gl)GTESHPPEDSWLK_
TAB1 Ubiquitylation K371 0.032 _LSQLGLDAGK(gl)IK_
TAB1 Ubiquitylation K373 -0.007 _LSQLGLDAGKIK(gl)_
TAB2 Phosphorylation S580 -0.075 _S(ph)NSISQIPSLEEMQQLR_
TAB2 Phosphorylation S582 0.331 _SNS(ph)ISQIPSLEEMQQLR_
TAB2 Ubiquitylation K653 -0.519 -0.200 _SIIK(gl)TPK_
TAB3 Phosphorylation S4 3.009 1.852 _(ac)AQS(ph)SPQLDIQVLHDLR_
TAB3 Phosphorylation S5 3.009 1.852 _(ac)AQS(ph)SPQLDIQVLHDLR_
TNIP1 Phosphorylation S77 -0.684 _DNELLPPPS(ph)PSLGSFDPLAELTGK_
TNIP1 Ubiquitylation K371 -0.625 _LLLAK(gl)SK_
TNIP1 Ubiquitylation K373 -0.353 _LLLAKSK(gl)_
TNIP1 Phosphorylation S403 0.455 0.424 _YLQDQLS(ph)PLTR_
UBA52 Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBA52 Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBA52 Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBA52 Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBA52 Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBA52 Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBA52 Ubiquitylation K93 0.181 2.418 _YNCDK(gl)MICR_
UBA52 Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBA52 Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBA52 Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBA52 Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBB Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBB Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBB Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBB Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBB Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBB Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBB Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBB Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBB Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBB Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBB Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBB Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBB Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBB Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBC Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBC Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBC Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBC Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBC Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBC Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBC Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBC Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBC Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBC Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBC Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBC Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBE2V1 Ubiquitylation K10 0.254 -0.318 _(ac)AATTGSGVK(gl)VPR_
UBE2V1 Ubiquitylation K129 0.440 0.709 _LMMSK(gl)ENMK_
UBE2V1 Ubiquitylation K291 -0.071 0.214 _IYSLK(gl)IECGPK_


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