bioLOGIC-db

bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

Query: TNIP1

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
W

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
TNIP1	0	-0.099	1.510	-0.910

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
TNIP1	Phosphorylation	S403	0.455	0.424	_YLQDQLS(ph)PLTR_
TNIP1	Ubiquitylation	K373		-0.353	_LLLAKSK(gl)_
TNIP1	Phosphorylation	S77		-0.684	_DNELLPPPS(ph)PSLGSFDPLAELTGK_
TNIP1	Ubiquitylation	K371	-0.625		_LLLAK(gl)SK_

Background Information for TNIP1:

Pubmed-TNIP1 »

Uniprot-TNIP1 »

Biogrid-TNIP1 »

ProteomicsDB-TNIP1 »

Tumorportal-TNIP1 »

COSMIC-TNIP1 »

GenomeRNAi-TNIP1 »

Genecards-TNIP1

Protein-protein Interactions for TNIP1

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait ABI2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CORO6	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CRHBP	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ERP44	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait EXOC1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait GRAP2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HAO2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait IKBIP	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait NAB2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PIGT	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SAMD4A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SYNC	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TNIP1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in TNIP1

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	ARM-type_fold	IPR016024	9.26

Protein complexes (CORUM database) featuring TNIP1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	5230	CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 complex	Database	0

Categories featuring TNIP1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0006412	translation	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0005488	binding	Database	9.32
Category members	GO Category	GO:0004843	ubiquitin-specific protease activity	Database	3.28
Category members	GO Category	GO:0006954	inflammatory response	Database	0.49
Category members	GO Category	GO:0006952	defense response	Database	0.32
Category members	GO Category	GO:0005622	intracellular	Database	0.32
Category members	GO Category	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Database	0.13
Category members	GO Category	GO:0051019	mitogen-activated protein kinase binding	Database	0.13
Category members	GO Category	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Database	0.1
Category members	GO Category	GO:0009101	glycoprotein biosynthetic process	Database	0.08
Category members	GO Category	GO:0050729	positive regulation of inflammatory response	Database	0.08
Category members	GO Category	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	Database	0
Category members	GO Category	GO:0007159	leukocyte cell-cell adhesion	Database	0
Category members	GO Category	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	Database	0
Category members	GO Category	GO:0045071	negative regulation of viral genome replication	Database	0