bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: USP7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP7 0 2.192 -0.600 0.590
USP7 0 2.192 -0.600 0.590 0.789 -0.077 0.319 -0.125 0.108

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP7 Ubiquitylation K605 1.273 _YTVFK(gl)VLK_
USP7 Ubiquitylation K944 0.512 0.702 _KAVELGEK(gl)ASGK_
USP7 Ubiquitylation K1106 0.275 0.509 _YTYLEK(gl)AIK_
USP7 Ubiquitylation K892 0.402 0.347 _KLYYQQLK(gl)MK_
USP7 Ubiquitylation K158 -0.447 0.111 _IINYRDDEK(gl)SFSR_
USP7 Ubiquitylation K834 -0.068 0.064 _MNYFQVAK(gl)TVAQR_
USP7 Phosphorylation S18 -0.616 -0.581 _AGEQQLS(ph)EPEDM(ox)EM(ox)EAGDTDDPPR_
USP7 Ubiquitylation K264 -1.350 _AVYMMPTEGDDSSK(gl)SVPLALQR_
USP7 Ubiquitylation K430 0.500 _FMYDPQTDQNIK(gl)INDR_
USP7 Ubiquitylation K879 -0.271 _DLLQFFK(gl)PR_
USP7 Ubiquitylation K894 0.380 _MK(gl)ITDFENRR_

Background Information for USP7:


Pubmed-USP7 »
Uniprot-USP7 »
Biogrid-USP7 »
ProteomicsDB-USP7 »

Tumorportal-USP7 »
COSMIC-USP7 »
GenomeRNAi-USP7 »
Genecards-USP7


Protein-protein Interactions for USP7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCOR Cat. description Hein, Mann, Cell 2015
Category members IP bait BRWD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait GPKOW Cat. description Hein, Mann, Cell 2015
Category members IP bait HUWE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUP Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF23 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCGF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RING1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TCEAL4 Cat. description Hein, Mann, Cell 2015
Category members IP bait TCF20 Cat. description Hein, Mann, Cell 2015
Category members IP bait USP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait USP7 Cat. description Hein, Mann, Cell 2015
Category members IP bait ACD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARHGEF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARL6IP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C14orf179 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ERCC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM170A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GAS2L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KHDRBS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LCOR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MEAF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NKAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUAK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PAK7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHF7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PJA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POTEB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POTEC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBPJ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSBN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RYBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCEAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCF25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM35 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSEN15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2E3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53
Category members MATH IPR002083 0
Category members TRAF-like IPR008974 0


Protein complexes (CORUM database) featuring USP7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0006283 transcription-coupled nucleotide-excision repair Database 6.58
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members Pathway Pathway_416 PID_P53_REGULATION_PATHWAY 0 2.29
Category members GO Category GO:0002039 p53 binding Database 2.06
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0016605 PML body Database 1.41
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members Pathway Pathway_118 PID_FOXO_PATHWAY 0 0.97
Category members GO Category GO:0004197 cysteine-type endopeptidase activity Database 0.38
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0032088 negative regulation of NF-kappaB transcription factor activity Database 0.04
Category members GO Category GO:0051090 regulation of sequence-specific DNA binding transcription factor activity Database 0.02
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0
Category members GO Category GO:0010216 maintenance of DNA methylation Database 0


.

© Copyright Svejstrup Laboratory 2015