Results for the Category
maintenance of DNA methylation
(GO:0010216)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| DNMT1 | 2 | 0.150 | -0.150 | 0.077 | -0.109 | -1.422 | 0.572 | |
| DNMT1 | 2 | 0.150 | -0.150 | 0.134 | -0.347 | -0.054 | ||
| CTCF | 1 | -0.190 | 0.040 | 1.656 | 0.503 | 0.229 | 0.942 | 0.519 |
| HELLS | 0 | -1.320 | 1.650 | -1.393 | -0.483 | -0.069 | -0.340 | -0.345 |
| USP7 | 0 | -0.600 | 0.590 | |||||
| USP7 | 0 | -0.600 | 0.590 | 0.789 | -0.077 | 0.319 | -0.125 | 0.108 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| DNMT1 | Phosphorylation | S127 | -0.755 | -0.836 | _VGM(ox)ADANS(ph)PPKPLSKPR_ |
| DNMT1 | Phosphorylation | S143 | 0.877 | 0.220 | _SKS(ph)DGEAKPEPSPSPR_ |
| DNMT1 | Phosphorylation | S152 | -0.685 | -1.347 | _SDGEAKPEPS(ph)PSPR_ |
| DNMT1 | Phosphorylation | S154 | -1.926 | -0.876 | _SDGEAKPEPSPS(ph)PR_ |
| DNMT1 | Ubiquitylation | K586 | 1.686 | 3.368 | _DLIK(gl)LAGVTLGQR_ |
| DNMT1 | Ubiquitylation | K675 | 1.267 | 0.915 | _DMVK(gl)FGGSGR_ |
| DNMT1 | Phosphorylation | S714 | -0.773 | -0.554 | _EADDDEEVDDNIPEMPS(ph)PKK_ |
| DNMT1 | Phosphorylation | S954 | -0.318 | 0.057 | _LSS(ph)PVKRPR_ |
| DNMT1 | Ubiquitylation | K961 | -3.166 | _K(gl)EPVDEDLYPEHYR_ | |
| DNMT1 | Ubiquitylation | K981 | -0.298 | -1.482 | _YSDYIK(gl)GSNLDAPEPYR_ |
| DNMT1 | Ubiquitylation | K997 | 0.042 | 0.154 | _IK(gl)EIFCPK_ |
| DNMT1 | Ubiquitylation | K1483 | 1.983 | -0.103 | _GVCSCVEAGK(gl)ACDPAAR_ |
| HELLS | Ubiquitylation | K74 | 0.655 | _LQHLLEK(gl)SNIYSK_ | |
| HELLS | Phosphorylation | S115 | 0.257 | _NS(ph)IDASEEKPVMR_ | |
| HELLS | Ubiquitylation | K474 | -0.723 | _EVVVYAPLSK(gl)K_ | |
| HELLS | Ubiquitylation | K475 | -0.723 | _EVVVYAPLSK(gl)K_ | |
| HELLS | Ubiquitylation | K753 | 0.741 | _NHFK(gl)GGQSGLNLSK_ | |
| HELLS | Ubiquitylation | K776 | 0.359 | _ELMELLK(gl)SR_ | |
| USP7 | Phosphorylation | S18 | -0.616 | -0.581 | _AGEQQLS(ph)EPEDM(ox)EM(ox)EAGDTDDPPR_ |
| USP7 | Ubiquitylation | K158 | -0.447 | 0.111 | _IINYRDDEK(gl)SFSR_ |
| USP7 | Ubiquitylation | K264 | -1.350 | _AVYMMPTEGDDSSK(gl)SVPLALQR_ | |
| USP7 | Ubiquitylation | K430 | 0.500 | _FMYDPQTDQNIK(gl)INDR_ | |
| USP7 | Ubiquitylation | K605 | 1.273 | _YTVFK(gl)VLK_ | |
| USP7 | Ubiquitylation | K834 | -0.068 | 0.064 | _MNYFQVAK(gl)TVAQR_ |
| USP7 | Ubiquitylation | K879 | -0.271 | _DLLQFFK(gl)PR_ | |
| USP7 | Ubiquitylation | K892 | 0.402 | 0.347 | _KLYYQQLK(gl)MK_ |
| USP7 | Ubiquitylation | K894 | 0.380 | _MK(gl)ITDFENRR_ | |
| USP7 | Ubiquitylation | K944 | 0.512 | 0.702 | _KAVELGEK(gl)ASGK_ |
| USP7 | Ubiquitylation | K1106 | 0.275 | 0.509 | _YTYLEK(gl)AIK_ |
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