bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: CTCF

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CTCF 1 3.889 -0.190 0.040 1.656 0.503 0.229 0.942 0.519

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CTCF:


Pubmed-CTCF »
Uniprot-CTCF »
Biogrid-CTCF »
ProteomicsDB-CTCF »

Tumorportal-CTCF »
COSMIC-CTCF »
GenomeRNAi-CTCF »
Genecards-CTCF


Protein-protein Interactions for CTCF
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLTSCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0020 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRR11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB48 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CTCF
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_C2H2-like IPR015880 1.29
Category members Znf_C2H2 IPR007087 0.92


Protein complexes (CORUM database) featuring CTCF
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1728 CTCF-nucleophosmin-PARP-HIS-KPNA-LMNA-TOP complex Database 0.63
Category members Corum 2705 SMAD3-SMAD4-CTCF protein-DNA complex Database 0
Category members Corum 5153 CTFC-TAF1 complex Database 0
Category members Corum 5154 CTCF-nucleophosmin complex Database 0


Categories featuring CTCF
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0006349 regulation of gene expression by genetic imprinting Database 1.64
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0000793 condensed chromosome Database 1.32
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0006306 DNA methylation Database 0.22
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members Disease phenotype Intellectual_disability Intellectual disability Database 0.04
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0010216 maintenance of DNA methylation Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0010629 negative regulation of gene expression Database 0
Category members GO Category GO:0016584 nucleosome positioning Database 0
Category members GO Category GO:0031060 regulation of histone methylation Database 0
Category members GO Category GO:0035065 regulation of histone acetylation Database 0
Category members GO Category GO:0040029 regulation of gene expression, epigenetic Database 0
Category members GO Category GO:0040030 regulation of molecular function, epigenetic Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0070602 regulation of centromeric sister chromatid cohesion Database 0


.

© Copyright Svejstrup Laboratory 2015