bioLOGIC-db

bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

Query: TRIM37

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
W

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
TRIM37	0	-1.023	0.060	0.540

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
TRIM37	Ubiquitylation	K693	-1.498	-0.586	_TDVK(gl)NTLSEIK_
TRIM37	Ubiquitylation	K679	-0.977	-0.642	_LK(gl)TQMAEVR_

Background Information for TRIM37:

Pubmed-TRIM37 »

Uniprot-TRIM37 »

Biogrid-TRIM37 »

ProteomicsDB-TRIM37 »

Tumorportal-TRIM37 »

COSMIC-TRIM37 »

GenomeRNAi-TRIM37 »

Genecards-TRIM37

Protein-protein Interactions for TRIM37

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait BBS7	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait C17orf59	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CDC16	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait NCAPH2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TPTE2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF211	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF214	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF263	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF416	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF550	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF610	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF816	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in TRIM37

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Bbox_C	IPR003649	0.18
Category members	Znf_B-box	IPR000315	0
Category members	Znf_RING	IPR001841	0
Category members	MATH	IPR002083	0
Category members	TRAF-like	IPR008974	0

Protein complexes (CORUM database) featuring TRIM37

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring TRIM37

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005829	cytosol	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	Pathway	Pathway_621	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	0	4.72
Category members	Pathway	Pathway_458	REACTOME_IMMUNE_SYSTEM	0	3
Category members	Pathway	Pathway_764	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	0	2.56
Category members	GO Category	GO:0031625	ubiquitin protein ligase binding	Database	2.54
Category members	Pathway	Pathway_888	KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS	0	2.22
Category members	Pathway	Pathway_832	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	0	1.58
Category members	GO Category	GO:0048471	perinuclear region of cytoplasm	Database	0.39
Category members	GO Category	GO:0005622	intracellular	Database	0.32
Category members	GO Category	GO:0008270	zinc ion binding	Database	0.29
Category members	GO Category	GO:0004842	ubiquitin-protein ligase activity	Database	0.24
Category members	GO Category	GO:0051865	protein autoubiquitination	Database	0.18
Category members	GO Category	GO:0005164	tumor necrosis factor receptor binding	Database	0.08
Category members	GO Category	GO:0046600	negative regulation of centriole replication	Database	0.06
Category members	GO Category	GO:0032088	negative regulation of NF-kappaB transcription factor activity	Database	0.04
Category members	GO Category	GO:0005777	peroxisome	Database	0
Category members	GO Category	GO:0016235	aggresome	Database	0
Category members	GO Category	GO:0042803	protein homodimerization activity	Database	0
Category members	GO Category	GO:0070842	aggresome assembly	Database	0